Registration Dossier
Registration Dossier
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EC number: 208-253-0 | CAS number: 518-47-8
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- publication
- Title:
- A Review of the Toxicity of Twelve Fluorescent Dyes Used for Water Tracing
- Author:
- P.L. Smart
- Year:
- 1 984
- Bibliographic source:
- The NSS Bulletin, Volume 46 Number 2: 21-33 - October 1984, A publication of the National Speleological Society
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: As mentioned below
- Principles of method if other than guideline:
- Skin irritation test of chemical Sodium Fluorescein was conducted.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Disodium 2-(3-oxo-6-oxidoxanthen-9-yl)benzoate
- EC Number:
- 208-253-0
- EC Name:
- Disodium 2-(3-oxo-6-oxidoxanthen-9-yl)benzoate
- Cas Number:
- 518-47-8
- Molecular formula:
- C20H12O5.2Na
- IUPAC Name:
- disodium 3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-3',6'-diolate
- Reference substance name:
- Sodium Fluorescein
- IUPAC Name:
- Sodium Fluorescein
- Test material form:
- other: Solid
- Details on test material:
- - Name of test material (as cited in study report):Sodium Fluorescein
- Molecular formula (if other than submission substance):C20H10O5.2Na
- Molecular weight (if other than submission substance):376.28
- Substance type:Organic
- Physical state:Solid
Constituent 1
Constituent 2
Test animals
- Species:
- other: Mammals
- Strain:
- not specified
- Details on test animals or test system and environmental conditions:
- No data available
Test system
- Type of coverage:
- not specified
- Preparation of test site:
- not specified
- Vehicle:
- not specified
- Controls:
- not specified
- Amount / concentration applied:
- No data available
- Duration of treatment / exposure:
- No data available
- Observation period:
- No data available
- Number of animals:
- No data available
- Details on study design:
- No data available
Results and discussion
In vivo
Results
- Irritation parameter:
- other: Not irritating
- Remarks on result:
- other: not irritating
- Other effects:
- No data available
Any other information on results incl. tables
No data available
Applicant's summary and conclusion
- Interpretation of results:
- not irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: not specified
- Conclusions:
- The test chemical Sodium Fluorescein was found to be non – irritating to skin.
- Executive summary:
The test chemical Sodium Fluorescein was found to be non – irritating to skin.
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