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Toxicological information

Skin irritation / corrosion

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Administrative data

Endpoint:
skin irritation: in vivo
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
publication
Title:
A Review of the Toxicity of Twelve Fluorescent Dyes Used for Water Tracing
Author:
P.L. Smart
Year:
1984
Bibliographic source:
The NSS Bulletin, Volume 46 Number 2: 21-33 - October 1984, A publication of the National Speleological Society

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: As mentioned below
Principles of method if other than guideline:
Skin irritation test of chemical Sodium Fluorescein was conducted.
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
Constituent
Test material form:
other: Solid
Details on test material:
- Name of test material (as cited in study report):Sodium Fluorescein
- Molecular formula (if other than submission substance):C20H10O5.2Na
- Molecular weight (if other than submission substance):376.28
- Substance type:Organic
- Physical state:Solid

Test animals

Species:
other: Mammals
Strain:
not specified
Details on test animals and environmental conditions:
No data available

Test system

Type of coverage:
not specified
Preparation of test site:
not specified
Vehicle:
not specified
Controls:
not specified
Amount / concentration applied:
No data available
Duration of treatment / exposure:
No data available
Observation period:
No data available
Number of animals:
No data available
Details on study design:
No data available

Results and discussion

In vivo

Results
Irritation parameter:
other: Not irritating
Remarks on result:
other: not irritating
Other effects:
No data available

Any other information on results incl. tables

No data available

Applicant's summary and conclusion

Interpretation of results:
not irritating
Remarks:
Migrated information Criteria used for interpretation of results: not specified
Conclusions:
The test chemical Sodium Fluorescein was found to be non – irritating to skin.
Executive summary:

The test chemical Sodium Fluorescein was found to be non – irritating to skin.