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EC number: 208-253-0
CAS number: 518-47-8
Classification of disodium
2-(3-oxo-6-oxidoxanthen-9-yl)benzoate for effects in the environment
In determining the classification
appropriate to disodium 2-(3-oxo-6-oxidoxanthen-9-yl)benzoate, it is
necessary to consider all available evidence concerning its persistence,
potential to accumulate and predicted or observed environmental fate and
behaviour that may present a long-term and/or delayed danger to the
structure and/or functioning of aquatic ecosystems. The
PBT assessment were based on toxicological information in conjunction
with standardized environmental fate- and bioaccumulation models. These
points are considered below.
Available data indicates that disodium
2-(3-oxo-6-oxidoxanthen-9-yl)benzoate is not persistent in the aquatic
and soil environment. Moreover, its persistent characteristic is only
observed in the sediment compartment and Fugacity modelling shows that
sediment is an important environmental fate (51.8% when estimated by EPI
Suite version 4.1). Hence it has been concluded that disodium
2-(3-oxo-6-oxidoxanthen-9-yl)benzoate is persistent in nature.
2-(3-oxo-6-oxidoxanthen-9-yl)benzoate is classified as a persistent
chemical (P) but not very persistent (not vP) since only estimated
half-life values for the same are available.
The estimated highest reported BCF
value of 75 L/kg wet wt. is lower than the threshold of 2000. The mean
log Kow was also below the threshold value of 4.5 (Log Kow = -1). Thus
it is concluded that disodium 2-(3-oxo-6-oxidoxanthen-9-yl)benzoate is
not expected to bioaccumulate in the food chain
2-(3-oxo-6-oxidoxanthen-9-yl)benzoate does not satisfies the criterion
for classification as bioaccumulative (B/ vB)
The toxicity values of fish,
invertebrates and algae are LC50 = 3000 and 1372-5000 mg/L, EC50 = 337;
377 and 165 mg/L and LC 50 = 209.24 and 108 mg/L, respectively. Also,
the LC0 values of fish is > 0.01 mg/L (3000 mg/L). These values suggest
classification for aquatic toxicity will not be applicable for all of
the tropic levels and the substance can be considered as not toxic for
marine/ freshwater organisms as per the criteria set out in Annex XIII.
In addition to aquatic toxicity, the
substance, disodium 2-(3-oxo-6-oxidoxanthen-9-yl)benzoate, is not
classified as carcinogenic (category 1A or 1B), germ cell mutagenic
(category 1A or 1B), or toxic for reproduction (category 1A, 1B or 2)
according to CLP (Regulation (EC) No 1272/2008) and there is no evidence
of chronic toxicity, as identified by the classifications STOT (repeated
exposure) according to Regulation (EC) No 1272/2008.
2-(3-oxo-6-oxidoxanthen-9-yl)benzoate does not meet the Annex XIII
criterion for classification as toxic (T).
Thus, in accordance with the
requirements of Annex XIII; it can be inferred that disodium
2-(3-oxo-6-oxidoxanthen-9-yl)benzoate is a not a PBT (including vPvB)
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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