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Ecotoxicological information

Short-term toxicity to fish

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Description of key information

The acute toxicity of 1,3-dihydro-4(or 5)-methyl-2H-benzimidazole-2-thione to fish (Danio rerio) was tested according to "Letale Wirkung beim Zebrabärbling -Brachydanio rerio-" (LC0 , LC50 , LC100; 48-96 Stunden) Verfahrensvorschlag: Umweltbundesamt Berlin, Stand Mai 1984. During 96 hours exposure the LC0 was measured at 22 mg/L and LC100 at 63 mg/L; and goemetric mean LC0/LC100 was calculated at 37.2 mg/L.

Key value for chemical safety assessment

LC50 for freshwater fish:
37.2 mg/L

Additional information

At defined concentrations of the substance arise after the testing period each percentages of dead fish. The LC0 and LC100 values ​​from this test will be determined directly, while the LC50-value calculation or graphically is determined from the dose-response curve.

Brachydanio rerio was exposed under static condition for 96 h to seven concentrations (7.8, 11, 16, 22, 31, 44 and 63 mg/L) of the test substance. The determination showed a LC0 at 22 mg/L and a LC100 at 63.0 mg/L, and the geometric mean LC0/LC100 was calculated at 37.2 mg/L