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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Description of key information

EC50 (48 hrs, Daphnia magna)_OECD guideline 202 (Daphnia sp. Acute Immobilisation Test) > 0.141 mg/L ( geom. mean of measured concentration) Limit test.
Since this concentration was considered to be around solubility of the substance,
EC50 48h (nominal) : > 100 mg/L

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
100 mg/L

Additional information

The GLP study was conducted as a limit test in order to confirm the effect of the test item on the test organisms at the concentration around the solubility of the test item in dilution water. Although one of the measured concentrations of the test item during the exposure was low (0.127 mgIL) compared with the solubility (0.181 mg/L) measured concurrently with the definitive study, it was thought that the concentrations of the test item in the test solution at the preparation were around the solubility because the values measured in the solubility study fluctuated and the concentration of 0.124 mg/L was in them. The measured concentrations at 24 hours after the preparation decreased but not so much as it was predicted from the result of the preliminary studies. Since no adverse effect was found under the condition in the definitive study, it was concluded that the test item had no adverse acute effect on the test organisms at the concentration around the solubility in dilution water. On the other hand, the concentration of 13F-EtOH which was hydrolyzed product of the test item tended to increase in test solution, and the measured concentrations were 0.0126 to 0.0459 mg/L. However, it was concluded that the hydrolyzed product had no adverse effect on the test organisms due to the result of the study.