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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: inhalation

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Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
migrated information: read-across based on grouping of substances (category approach)
Adequacy of study:
supporting study
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: Summary table with LC50 values from literature. LD50 in mg/kg following intratracheal dosing is not relevant for this endpoint.

Data source

Reference
Reference Type:
publication
Title:
No information
Author:
RTECS
Year:
1982
Bibliographic source:
Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982

Materials and methods

Test material

Constituent 1
Reference substance name:
Sodium thiocyanate
EC Number:
208-754-4
EC Name:
Sodium thiocyanate
Cas Number:
540-72-7
IUPAC Name:
sodium thiocyanate

Results and discussion

Applicant's summary and conclusion

Conclusions:
There is one reference in RTECS indicating that the LD50 of sodium thiocyanate in rat is 232 mg/kgbw following intratracheal dosing.
Executive summary:

Summary table from RTECS indicating sodium thiocyanate lethality via inhalation.

 

Organism

Dose

Reference

Rat

LD50 232 mg/kg (intratracheal)

"Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., , Centre of International Projects, GKNT, 1982