Korábbi/eredmények

Korábbi/eredmények

Korábbi/eredmények

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

There are currently no ongoing consultations.
 
3-acetoxymethylen-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 213-485-0 957-68-6
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
10/08/2018
10/08/2018
10/08/2018
24/09/2018
24/09/2018
24/09/2018
Details
3-amino-4-octanol  482-070-6 1001354-72-8 Reproductive toxicity (developmental toxicity) 19/11/2010 03/01/2011 Details
3-aminopropyldiethylamine 203-236-4 104-78-9
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
21/03/2014
21/03/2014
05/05/2014
05/05/2014
Details
3-aminopropyltriethoxysilane 213-048-4 919-30-2
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
18/03/2021
18/03/2021
03/05/2021
03/05/2021
Details
3-C12-14-(even numbered)-alkylamido-N,N-dimethylpropan-1-amino oxide 931-324-9 - Sub-chronic toxicity (90-day): oral 02/09/2011 17/10/2011 Details
3-C12-18-(even numbered)-alkylamido-N,N-dimethylpropan-1-amino oxide 939-581-9 - Reproductive toxicity (pre-natal developmental toxicity) 26/03/2018 11/05/2018 Details
3-chloropropyltrimethoxysilane 219-787-9 2530-87-2
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
26/08/2021
26/08/2021
11/10/2021
11/10/2021
Details
3-Ethenyl-5-methyl-2-oxazolidinone 809-852-5 3395-98-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
27/09/2017
27/09/2017
13/11/2017
13/11/2017
Details
3-ethyloxetane-3-methanol 221-254-0 3047-32-3 Long-term toxicity to fish 03/10/2023 17/11/2023 Details
3-ethyloxetane-3-methanol 221-254-0 3047-32-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
31/01/2014
31/01/2014
17/03/2014
17/03/2014
Details
3-hydroxy-1,1-dimethylbutyl 2-ethyl-2-methylheptaneperoxoate 413-910-1 95718-78-8
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/04/2012
17/04/2012
17/04/2012
01/06/2012
01/06/2012
01/06/2012
Details
3-hydroxy-2,2-dimethylpropyl 3-hydroxy-2,2-dimethylpropionate 214-222-2 1115-20-4
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
31/05/2011
31/05/2011
31/05/2011
15/07/2011
15/07/2011
15/07/2011
Details
3-hydroxy-2-(3-hydroxy-2-quinolyl)-1H-inden-1-one 241-753-7 17772-51-9 Reproductive toxicity (pre-natal developmental toxicity) 31/08/2015 15/10/2015 Details
3-hydroxy-2-(hydroxymethyl)-2-methylpropanal 242-393-3 18516-18-2
Genetic toxicity in vivo
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/06/2011
16/06/2011
16/06/2011
16/06/2011
01/08/2011
01/08/2011
01/08/2011
01/08/2011
Details
3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate, oligomers, reaction products with 2-butanone oxime 500-287-7 103170-26-9 Sub-chronic toxicity (90 day): inhalation 12/12/2014 26/01/2015 Details
3-mercaptopropionic acid 203-537-0 107-96-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
04/09/2023
04/09/2023
19/10/2023
19/10/2023
Details
3-methoxy-3-methylbutan-1-ol 260-252-4 56539-66-3 Sub-chronic toxicity (90-day): oral 18/09/2014 03/11/2014 Details
3-methoxy-3-methylbutan-1-ol 260-252-4 56539-66-3 Long-term toxicity to fish 26/10/2022 12/12/2022 Details
3-methoxy-3-methylbutan-1-ol 260-252-4 56539-66-3 Reproductive toxicity (extended one-generation reproductive toxicity study) 30/09/2021 15/11/2021 Details
3-methylbutan-1-ol 204-633-5 123-51-3 Long-term toxicity to fish||Note: testing proposed with Pentan-1-ol (EC no. 200-752-1) 22/09/2022 07/11/2022 Details
3-methylbutanone 209-264-3 563-80-4 Sub-chronic toxicity (90 day): inhalation 14/08/2014 28/09/2014 Details
3-methyldecane; benzene; cyclooctane; nonane 941-364-9 - Reproductive toxicity (extended one-generation reproductive toxicity study) 05/07/2018 20/08/2018 Details
3-methylpentane-1,5-diol 224-709-1 4457-71-0 Long-term toxicity to fish 01/03/2023 17/04/2023 Details
3-Pentanone, 1,1,1,2,2,4,5,5-nonafluoro-4-(trifluoromethyl )- 436-710-6 756-13-8 Reproductive toxicity (pre-natal developmental toxicity) 15/03/2011 29/04/2011 Details
3-Sulfanylpropanoic acid 203-537-0 107-96-0
Reproductive toxicity (developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
05/04/2011
05/04/2011
05/04/2011
20/05/2011
20/05/2011
20/05/2011
Details
3-trimethoxysilylpropane-1-thiol 224-588-5 4420-74-0 Long-term toxicity to fish||Note: testing proposed with 3-Triethoxysilylpropane-1-thiol (EC no. 238-883-1) 22/09/2022 07/11/2022 Details
3-trimethoxysilylpropane-1-thiol 224-588-5 4420-74-0
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 3-(triethoxysilyl)propanethiol (EC 238-883-1) || Note: Testing proposal is based on concern identified by the registrant.
Sub-chronic toxicity (90-day): oral || Note: testing proposed with 3-(triethoxysilyl)propanethiol (EC 238-883-1) || Note: Testing proposal is based on concern identified by the registrant.
23/11/2020
23/11/2020
07/01/2021
07/01/2021
Details
3-trimethoxysilylpropyl methacrylate 219-785-8 2530-85-0
Genetic toxicity in vivo
Reproductive toxicity (extended one-generation reproductive toxicity study)
01/09/2017
01/09/2017
16/10/2017
16/10/2017
Details
3-trimethoxysilylpropyl methacrylate 219-785-8 2530-85-0
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): inhalation
15/04/2011
15/04/2011
30/05/2011
30/05/2011
Details
3-trimethoxysilylpropyl methacrylate 219-785-8 2530-85-0 Reproductive toxicity (pre-natal developmental toxicity) 26/04/2019 10/06/2019 Details
3-{[3-(C10-16-oxy)propyl]amino}propan-1-aminium acetate 941-152-6 - Sub-chronic toxicity (90-day): oral||Note: testing proposed with 1,3-propanediamine, N-[3-((C11-14, C13-rich)oxy)propyl]-branched acetate (EC: 931-295-2) 15/07/2022 29/08/2022 Details
3a,4,7,7a-tetrahydro-4,7-methanoindene 201-052-9 77-73-6 Reproductive toxicity (pre-natal developmental toxicity) 28/02/2019 15/04/2019 Details
4'-Ethyl-2,3-difluorbiphenyl-4-boronic acid 929-209-3 - Genetic toxicity in vivo 16/12/2020 01/02/2021 Details
4'-hydroxyacetophenone 202-802-8 99-93-4 Reproductive toxicity (pre-natal developmental toxicity) 25/10/2017 11/12/2017 Details
4,4'-(9H-fluoren-9-ylidene)bis(2-chloroaniline) 407-560-9 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/06/2020
17/06/2020
03/08/2020
03/08/2020
Details
4,4'-(9H-fluoren-9-ylidene)bis(2-chloroaniline) 407-560-9 107934-68-9 Bioaccumulation aquatic / sediment || Note: Testing proposal is based on concern identified by the registrant. 16/10/2014 01/12/2014 Details
4,4'-[(isopropylidene)bis(p-phenyleneoxy)]diphthalic dianhydride 253-781-7 38103-06-9 Sub-chronic toxicity (90-day): oral 27/01/2020 12/03/2020 Details
4,4'-[2,2,2-trifluoro-1-(trifluoromethyl)ethylidene]diphenol; bisphenol AF 216-036-7 1478-61-1 Genetic toxicity in vivo 23/11/2020 07/01/2021 Details
4,4'-isopropylidenedi-o-cresol 201-240-0 79-97-0 Genetic toxicity in vivo 25/05/2020 09/07/2020 Details
4,4'-isopropylidenedicyclohexanol 201-244-2 80-04-6 Long-term toxicity to fish 17/06/2014 01/08/2014 Details
4,4'-isopropylidenedicyclohexanol 201-244-2 80-04-6 Genetic toxicity in vivo 16/12/2020 01/02/2021 Details
4,4'-isopropylidenedicyclohexanol 201-244-2 80-04-6 Reproductive toxicity (pre-natal developmental toxicity) 06/09/2018 22/10/2018 Details
4,4'-Isopropylidenedicyclohexanol, oligomeric reaction products with 1-chloro-2,3-epoxypropane 500-070-7 30583-72-3
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/06/2014
02/06/2014
02/06/2014
02/06/2014
17/07/2014
17/07/2014
17/07/2014
17/07/2014
Details
4,4'-Isopropylidenediphenol, ethoxylated 500-082-2 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
21/05/2018
21/05/2018
21/05/2018
05/07/2018
05/07/2018
05/07/2018
Details
4,4'-Isopropylidenediphenol, ethoxylated 500-082-2 32492-61-8
Genetic toxicity in vivo
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
16/06/2022
16/06/2022
16/06/2022
01/08/2022
01/08/2022
01/08/2022
Details
4,4'-Isopropylidenediphenol, ethoxylated, esters with fatty acids, coco 500-303-2 115340-85-7 Genetic toxicity in vivo 21/01/2021 08/03/2021 Details
4,4'-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, esters with acrylic acid 500-130-2 55818-57-0 Reproductive toxicity (pre-natal developmental toxicity) 31/05/2016 15/07/2016 Details
4,4'-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, reaction products with 2-methylimidazole 500-181-0 68002-42-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/09/2014
18/09/2014
03/11/2014
03/11/2014
Details
4,4'-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, reaction products with 3-aminomethyl-3,5,5-trimethylcyclohexylamine 500-101-4 38294-64-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/04/2014
15/04/2014
30/05/2014
30/05/2014
Details
4,4'-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, reaction products with fatty acids, C18-unsatd., dimers 500-180-5 67989-52-0
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
02/06/2014
02/06/2014
02/06/2014
17/07/2014
17/07/2014
17/07/2014
Details
4,4'-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, reaction products with maleic anhydride and methacrylic acid 500-090-6 36425-16-8
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with a structurally related substance (small vinyl ester)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with a structurally related substance (small vinyl ester)
31/05/2016
31/05/2016
15/07/2016
15/07/2016
Details
4,4'-methylenebis[2,6-diethylaniline] 237-185-4 13680-35-8
Genetic toxicity in vivo
Long-term toxicity to fish
26/03/2018
26/03/2018
11/05/2018
11/05/2018
Details
4,4'-methylenebis[N,N-bis(2,3-epoxypropyl)aniline] 249-204-3 28768-32-3
Reproduction toxicity (two generation reproductive toxicity)
Reproductive toxicity (developmental toxicity)
Sub-chronic toxicity (90-day): dermal
26/01/2011
26/01/2011
26/01/2011
14/03/2011
14/03/2011
14/03/2011
Details
4,4'-methylenebis[N-sec-butylaniline] 226-122-6 5285-60-9 Bioaccumulation aquatic / sediment 27/01/2020 12/03/2020 Details
4,4'-methylenedi-2,6-xylenol 226-378-9 5384-21-4 Reproductive toxicity (extended one-generation reproductive toxicity study) 03/04/2023 22/05/2023 Details
4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/11/2021 10/01/2022 Details
4,4'-methylenediphenyl diisocyanate and its oligomeric reaction products with oxydipropanol and [(methylethylene)bis(oxy)]dipropanol 701-072-2 - Reproductive toxicity (extended one-generation reproductive toxicity study)|| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no: 202-966-0) 16/06/2022 01/08/2022 Details
4,4'-Methylenediphenyl diisocyanate, oligomeric reaction products with 2,4'-diisocyanatodiphenylmethane 500-297-1 109331-54-6 Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0) 31/01/2023 17/03/2023 Details
4,4'-Methylenediphenyl diisocyanate, oligomers 500-040-3 25686-28-6 Reproductive toxicity (extended one-generation reproductive toxicity study)|| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0) 16/06/2022 01/08/2022 Details
4,4'-oxydi(benzenesulphonohydrazide) 201-286-1 80-51-3
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
21/03/2014
21/03/2014
21/03/2014
05/05/2014
05/05/2014
05/05/2014
Details
4,4'-sulfonyldiphenol 201-250-5 80-09-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/04/2011
15/04/2011
30/05/2011
30/05/2011
Details
4,4'-sulphonyldiphenol 201-250-5 80-09-1 Long-term toxicity to fish 16/06/2022 01/08/2022 Details
4,4,13,13-tetraethoxy-3,14-dioxa-8,9-dithia-4,13-disilahexadecane 260-350-7 56706-10-6
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/03/2011
15/03/2011
29/04/2011
29/04/2011
Details
4,4,13,13-tetraethoxy-3,14-dioxa-8,9-dithia-4,13-disilahexadecane 260-350-7 56706-10-6
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
23/04/2018
23/04/2018
07/06/2018
07/06/2018
Details
4,4,7,7-tetraethoxy-3,8-dioxa-4,7-disiladecane 240-212-2 16068-37-4
Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/06/2020
17/06/2020
17/06/2020
17/06/2020
03/08/2020
03/08/2020
03/08/2020
03/08/2020
Details
4,4`-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, reaction products with methacrylic acid 500-089-0 36425-15-7
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
01/07/2011
01/07/2011
01/07/2011
15/08/2011
15/08/2011
15/08/2011
Details
4,6-dichloro-N-(1,1,3,3-tetramethylbutyl)-1,3,5-triazin-2-amine 276-309-1 72058-41-4
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
23/11/2020
23/11/2020
07/01/2021
07/01/2021
Details
4,8-Dimethyl-2,5,7,10-tetraoxaundecane 813-999-0 59039-15-5 Long-term toxicity to fish 30/06/2023 14/08/2023 Details
4-((Triethoxysilyl)methyl) morpholine 480-370-1 21743-27-1
Reproductive toxicity (developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day)
27/11/2009
27/11/2009
27/11/2009
11/01/2010
11/01/2010
11/01/2010
Details
4-(1,1-dimethylethyl)cyclohexyl acrylate 282-104-8 84100-23-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
23/03/2020
23/03/2020
07/05/2020
07/05/2020
Details
4-(1-methyl-1-phenylethyl)-N-[4-(1-methyl-1-phenylethyl)phenyl]aniline 233-215-5 10081-67-1 Sub-chronic toxicity (90-day): oral 18/02/2014 04/04/2014 Details
4-(1-oxo-2-propenyl)-morpholine 418-140-1 5117-12-4 Genetic toxicity in vivo 21/09/2020 05/11/2020 Details
4-(4-isopropoxyphenylsulfonyl)phenol 405-520-5 95235-30-6 Reproductive toxicity (pre-natal developmental toxicity) 24/08/2020 08/10/2020 Details
4-[3-(1-naphthylamino)propyl]morpholine 226-033-2 5235-82-5 Genetic toxicity in vivo 19/10/2020 03/12/2020 Details
4-[[4-(aminocarbonyl)phenyl]azo]-N-(2-ethoxyphenyl)-3-hydroxynaphthalene-2-carboxamide – nano form 220-509-3 2786-76-7 Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with [3-hydroxy-N-(o-tolyl)-4-[(2,4,5-trichlorophenyl)azo]naphthalene-2-carboxamide] (EC no. 229-440-3) 03/10/2023 17/11/2023 Details
4-chloroformylphthalic anhydride 214-874-8 1204-28-0 Genetic toxicity in vivo
|| Note: Testing proposal is based on concern identified by the registrant.
27/01/2020 12/03/2020 Details
4-fluoro-1,3-dioxolan-2-one 483-360-5 114435-02-8 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 24/07/2019 09/09/2019 Details
4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl 218-760-9 2226-96-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
14/08/2014
14/08/2014
28/09/2014
28/09/2014
Details
4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl 218-760-9 2226-96-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/02/2015
16/02/2015
02/04/2015
02/04/2015
Details
4-hydroxy-4-methylpentan-2-one 204-626-7 123-42-2
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
01/09/2016
01/09/2016
17/10/2016
17/10/2016
Details
4-hydroxybenzophenone 214-507-1 1137-42-4 Genetic toxicity in vivo 18/02/2021 05/04/2021 Details
4-methylmorpholine 203-640-0 109-02-4 Sub-chronic toxicity (90-day): oral 25/11/2021 10/01/2022 Details
4-methylmorpholine 4-oxide, monohydrate 231-391-8 7529-22-8
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
16/02/2015
16/02/2015
16/02/2015
02/04/2015
02/04/2015
02/04/2015
Details
4-methylpentan-2-one 203-550-1 108-10-1 Long-term toxicity to fish 06/06/2023 21/07/2023 Details
4-methylthiosemicarbazide 229-563-2 6610-29-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/09/2014
18/09/2014
03/11/2014
03/11/2014
Details
4-morpholinecarbaldehyde 224-518-3 4394-85-8
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
10/05/2022
10/05/2022
27/06/2022
27/06/2022
Details
4-morpholinecarbaldehyde 224-518-3 4394-85-8 Sub-chronic toxicity (90-day): oral 04/04/2014 19/05/2014 Details
4-nitrotoluene-2-sulphonic acid 204-445-3 121-03-9
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/04/2011
15/04/2011
30/05/2011
30/05/2011
Details
4-oxovaleric acid 204-649-2 123-76-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
10/12/2018
10/12/2018
24/01/2019
24/01/2019
Details
4-phenylbutan-2-one 219-847-4 2550-26-7 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with a read-across substance having similar formula structure and its carbon chain consists of even number of carbons 22/11/2017 08/01/2018 Details
4-phenylbutenone 204-555-1 122-57-6 Genetic toxicity in vivo 23/03/2020 07/05/2020 Details
4-tert-butylcyclohexyl acetate 250-954-9 32210-23-4 Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with cis-4-tert-butylcyclohexyl acetate
24/02/2020 09/04/2020 Details
4-tert-butylpyrocatechol 202-653-9 98-29-3
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
29/04/2011
29/04/2011
29/04/2011
14/06/2011
14/06/2011
14/06/2011
Details
4-tert-butylpyrocatechol 202-653-9 98-29-3
Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (extended one-generation reproductive toxicity study)
28/02/2018
28/02/2018
16/04/2018
16/04/2018
Details
4-trans-Propyl-4-trans-vinyl-[1,1-bicylohexyl] 601-409-2 116020-44-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
25/06/2015
25/06/2015
10/08/2015
10/08/2015
Details
5,5'-dithiodi-1,3,4-thiadiazole-2(3H)-thione 276-763-0 72676-55-2 Long-term toxicity to fish 30/06/2023 14/08/2023 Details
5,5'-dithiodi-1,3,4-thiadiazole-2(3H)-thione 276-763-0 72676-55-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/12/2020
16/12/2020
01/02/2021
01/02/2021
Details
5,5'-dithiodi-1,3,4-thiadiazole-2(3H)-thione 276-763-0 72676-55-2 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 20/10/2016 05/12/2016 Details
5-amino-2-nitrobenzoic acid 236-283-4 13280-60-9 Genetic toxicity in vivo 25/01/2022 11/03/2022 Details
5-bromo-5-nitro-1,3-dioxane 250-001-7 30007-47-7 Genetic toxicity in vivo 19/10/2020 03/12/2020 Details
5-ethyl-1,3-dioxane-5-methanol 225-967-8 5187-23-5
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
31/01/2014
31/01/2014
17/03/2014
17/03/2014
Details
5-ethyl-1,3-dioxane-5-methanol 225-967-8 5187-23-5
Long-term toxicity to fish
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
03/10/2023
03/10/2023
03/10/2023
17/11/2023
17/11/2023
17/11/2023
Details
5-Methoxy-2-tetralone 457-080-9 - Genetic toxicity in vivo 06/09/2018 22/10/2018 Details
5-methylheptan-3-one 208-793-7 541-85-5
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): inhalation
03/03/2014
03/03/2014
17/04/2014
17/04/2014
Details
5-methylhexan-2-one 203-737-8 110-12-3 Reproductive toxicity (pre-natal developmental toxicity) 14/02/2011 31/03/2011 Details
5-sulphosalicylic acid 202-555-6 97-05-2 Genetic toxicity in vivo 10/05/2022 27/06/2022 Details
6'-(dibutylamino)-3'-methyl-2'-(phenylamino)spiro[isobenzofuran-1(3H),9-(9H)-xanthen]-3-one 403-830-5 89331-94-2 Sub-chronic toxicity (90-day): oral 26/03/2018 11/05/2018 Details
6'-(dibutylamino)-3'-methyl-2'-(phenylamino)spiro[isobenzofuran-1(3H),9-(9H)-xanthen]-3-one 403-830-5 89331-94-2 Bioaccumulation aquatic / sediment 12/06/2015 27/07/2015 Details
6'-(dibutylamino)-3'-methyl-2'-(phenylamino)spiro[isobenzofuran-1(3H),9-(9H)-xanthen]-3-one 403-830-5 89331-94-2
Bioaccumulation aquatic / sediment
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
23/04/2018
23/04/2018
23/04/2018
07/06/2018
07/06/2018
07/06/2018
Details
6'-(dibutylamino)-3'-methyl-2'-(phenylamino)spiro[isobenzofuran-1(3H),9-(9H)-xanthen]-3-one 403-830-5 89331-94-2 Sub-chronic toxicity (90-day): oral 02/09/2013 18/10/2013 Details
6,15-dihydroanthrazine-5,9,14,18-tetrone 201-375-5 81-77-6 Reproductive toxicity (pre-natal developmental toxicity) 14/08/2014 28/09/2014 Details
6,6'-di-tert-butyl-2,2'-methylenedi-p-cresol 204-327-1 119-47-1 Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018 Details
6,6`-di-tert-butyl-2,2`-methylenedi-p-cresol 204-327-1 119-47-1 Reproductive toxicity (two-generation reproductive toxicity) 16/05/2011 30/06/2011 Details
6,8-Dioxabicyclo[3.2.1]octan-4-one, (1S,5R) (Cyrene) 807-130-4 53716-82-8
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
26/08/2021
26/08/2021
11/10/2021
11/10/2021
Details
6-(cyclohexylamino)-3-methyl-3H-dibenz[f,ij]isoquinoline-2,7-dione 244-320-0 21295-57-8 Genetic toxicity in vivo 26/08/2021 11/10/2021 Details
6-(isononanoylamino)hexanoic acid, compound with 2,2',2''-nitrilotriethanol (1:1) 701-138-0 242482-67-3 Reproductive toxicity (pre-natal developmental toxicity) 01/09/2017 16/10/2017 Details
6-[(1-oxomethyloctyl)amino]hexanoic acid 276-173-3 71902-23-3 Reproductive toxicity (pre-natal developmental toxicity) 10/03/2017 25/04/2017 Details
6-methyl-1,3,5-triazine-2,4-diyldiamine 208-796-3 542-02-9 Reproductive toxicity (pre-natal developmental toxicity) 21/03/2014 05/05/2014 Details
6-phenyl-1,3,5-triazine-2,4-diamine 202-095-6 91-76-9 Reproductive toxicity (two-generation reproductive toxicity) Reproductive toxicity (pre-natal developmental toxicity) 12/06/2013 29/07/2013 Details
6-tert-butyl-2,4-xylenol 217-533-1 1879-09-0
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
18/02/2021
18/02/2021
05/04/2021
05/04/2021
Details
6-tert-butyl-2,4-xylenol 217-533-1 1879-09-0 Long-term toxicity to fish 15/07/2014 29/08/2014 Details
7,7,9(or 7,9,9)-trimethyl-4,13-dioxo-3,14-dioxa-5,12-diazahexadecane-1,16-diyl bismethacrylate 276-957-5 72869-86-4 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 19/10/2020 03/12/2020 Details
7-amino-3,8-bis-[4-(2-sulfoxyethylsulfonyl)-2-sulfophenylazo]-4-hydroxynaphthalene-2-sulfonic acid, Na/K salt; 7-amino-3-[4-(2-sulfoxyethylsulfonyl)phenylazo]-4-hydroxy-8-[4-(2-sulfoxyethylsulfonyl)-2-sulfophenylazo]naphthalene-2-sulfonic acid, Na/K salt; 7-amino-8-[4-(2-sulfoxyethylsulfonyl)-phenylazo]-4-hydroxy-3-[4-(2-sulfoxyethylsulfonyl)-2-sulfophenylazo]naphthalene-2-sulfonic acid, Na/K salt; reaction mass of: 7-amino-3,8-bis-[4-(2-sulfoxyethylsulfonyl)phenylazo]-4-hydroxynaphthalene-2-sulfonic acid, Na/K salt 429-070-4 - Sub-chronic toxicity (90-day): oral 22/04/2021 07/06/2021 Details
7-hydroxycitronellal 203-518-7 107-75-5
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
31/01/2023
31/01/2023
31/01/2023
17/03/2023
17/03/2023
17/03/2023
Details
8,9,10,11-tetrachloro-12H-phthaloperin-12-one 244-007-9 20749-68-2 Reproductive toxicity (pre-natal developmental toxicity) 14/08/2014 28/09/2014 Details
8,9,10-trinorborn-2-ene 207-866-0 498-66-8
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/06/2011
16/06/2011
01/08/2011
01/08/2011
Details
8,9,10-trinorborn-2-ene 207-866-0 498-66-8
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
01/11/2015
01/11/2015
16/12/2015
16/12/2015
Details
9-Octadecenoic acid (Z)-, sulfonated, potassium salts 271-843-1 68609-93-8
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
16/02/2015
16/02/2015
16/02/2015
02/04/2015
02/04/2015
02/04/2015
Details
[1,3(or 1,4)-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide 246-678-3 25155-25-3 Reproductive toxicity (extended one-generation reproductive toxicity study) 27/05/2019 11/07/2019 Details
[1,3(or 1,4)-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide 246-678-3 25155-25-3
Bioaccumulation aquatic / sediment
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
06/03/2012
06/03/2012
06/03/2012
20/04/2012
20/04/2012
20/04/2012
Details
[1,3(or 1,4)-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide 246-678-3 25155-25-3 Reproductive toxicity (pre-natal developmental toxicity) 30/11/2015 14/01/2016 Details
[1,3-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide 218-664-7 2212-81-9
Bioaccumulation aquatic / sediment
Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant
20/10/2016
20/10/2016
05/12/2016
05/12/2016
Details
[1,3-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide 218-664-7 2212-81-9 Reproductive toxicity (extended one-generation reproductive toxicity study) “|| Note: testing proposed with [1,3(or 1,4)-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide CAS: 25155-25-3)” 25/05/2020 09/07/2020 Details
[1,3-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide 218-664-7 2212-81-9
Bioaccumulation aquatic / sediment
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/05/2012
16/05/2012
16/05/2012
02/07/2012
02/07/2012
02/07/2012
Details
[1R-(1α,2β,5α)]-1-(isopropyl)-2-methoxy-4-methylcyclohexane 216-365-6 1565-76-0 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 19/10/2020 03/12/2020 Details
[1α(E),2β]-1-(2,6,6-trimethylcyclohex-3-en-1-yl)but-2-en-1-one 275-156-8 71048-82-3 Reproductive toxicity (pre-natal developmental toxicity) 26/10/2022 12/12/2022 Details
[3-(2,3-epoxypropoxy)propyl]diethoxymethylsilane 220-780-8 2897-60-1 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 16/12/2016 30/01/2017 Details
[3-(2,3-epoxypropoxy)propyl]triethoxysilane 220-011-6 2602-34-8 Genetic toxicity in vivo 18/03/2021 03/05/2021 Details
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane 219-784-2 2530-83-8 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 17/06/2020 03/08/2020 Details
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane 219-784-2 2530-83-8 Genetic toxicity in vivo 16/02/2015 02/04/2015 Details
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane 219-784-2 2530-83-8 Genetic toxicity in vivo 01/08/2012 17/09/2012 Details
[3-(triethoxysilyl)propyl]urea 245-876-7 23779-32-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/04/2015
17/04/2015
04/06/2015
04/06/2015
Details
[3-(trimethoxysilyl)propyl]urea 245-904-8 23843-64-3 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Urea, N-(3-silylpropyl)-, Si-(ethoxy and methoxy) derivs., (EC 601-461-6) || Note: Testing proposal is based on concern identified by the registrant 07/07/2020 21/08/2020 Details
[3aR-(3aα,5aβ,9aα,9bβ)]-dodecahydro-3a,6,6,9a-tetramethylnaphtho[2,1-b]furan 229-861-2 6790-58-5 Long-term toxicity to fish 22/09/2022 07/11/2022 Details
[4-[p,p'-bis(dimethylamino)benzhydrylidene]cyclohexa-2,5-dien-1-ylidene]dimethylammonium m-[[p-anilinophenyl]azo]benzenesulphonate 265-449-9 65113-55-5
Genetic toxicity in vivo
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/02/2014
18/02/2014
18/02/2014
18/02/2014
04/04/2014
04/04/2014
04/04/2014
04/04/2014
Details
[[(phosphonomethyl)imino]bis[ethylenenitrilobis(methylene)]]tetrakisphosphonic acid, ammonium salt 274-798-6 70714-66-8 Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Sodium salts of [[(phosphonomethyl)imino]bis[ethane-2,1-diylnitrilobis(methylene)]]tetrakisphosphonic acid (5-7 Na:1) (EC no. 701-216-4) 01/03/2023 17/04/2023 Details
[[(phosphonomethyl)imino]bis[hexamethylenenitrilobis(methylene)]]tetrakisphosphonic acid 252-156-6 34690-00-1
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with either the registered substance or a read-across substance, which would be a salt of the same phosphonic acid; or salt of a structurally analogous phosphonic acid, HMDTMP
Sub-chronic toxicity (90-day): oral || Note: testing proposed with either the registered substance or a read-across substance, which would be a salt of the same phosphonic acid; or salt of a structurally analogous phosphonic acid, HMDTMP
31/01/2018
31/01/2018
19/03/2018
19/03/2018
Details
[[(phosphonomethyl)imino]bis[hexamethylenenitrilobis(methylene)]]tetrakisphosphonic acid 252-156-6 34690-00-1
Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant.
Sub-chronic toxicity (90-day): oral || Note: Testing proposal is based on concern identified by the registrant.
20/05/2015
20/05/2015
06/07/2015
06/07/2015
Details
[hexane-1,6-diylbis[nitrilobis(methylene)]]tetrakisphosphonic acid, potassium salt 254-135-7 38820-59-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
14/08/2014
14/08/2014
28/09/2014
28/09/2014
Details
[No public or meaningful name is available] 944-258-0 1850357-57-1 Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Wax, rice bran, oxidized (Polar modified Rice Bran Wax) 03/05/2023 19/06/2023 Details
A dried sludge product resulting from the treatment process of domestic wastewater. The exact processes followed for the production of the dried sludge are: Preliminary and secondary treatment of the wastewater stream, thickening, dehydration and drying of the excess sludge. 943-834-9 -
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
03/04/2023
03/04/2023
03/04/2023
22/05/2023
22/05/2023
22/05/2023
Details
A mixture of cis- and trans-cyclohexadec-8-en-1-one 401-700-2 3100-36-5
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
28/11/2022
28/11/2022
28/11/2022
12/01/2023
12/01/2023
12/01/2023
Details
A mixture of isomers of branched tetracosane 417-060-2 151006-61-0
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 1-decene, dimer (EC 917-709-4), Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1) and 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9), 1-Dodecene, Dimer (EC 814-509-8 ) and Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) and 1-Dodecene, dimer, hydrogenated (EC 604-768-3)
01/07/2021
01/07/2021
01/07/2021
16/08/2021
16/08/2021
16/08/2021
Details
A mixture of: bis[4-diphenylsulfoniumphenyl]sulfide-bishexafluoroantimonate; thiophenoxyphenylsulfonium hexafluoroantimonate 403-500-0 159120-95-3 Genetic toxicity in vivo 03/10/2023 17/11/2023 Details
A mixture of: cis-tetrahydro-2-isobutyl-4-methylpyran-4-ol; trans-tetrahydro-2-isobutyl-4-methylpyran-4-ol 405-040-6 63500-71-0 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/06/2015 10/08/2015 Details
a mixture of: cistetrahydro-2-isobutyl-4-methylpyran-4-ol,transtetrahydro-2-isobutyl-4-methylpyran-4-ol 405-040-6 63500-71-0
(90-day): oral
Reproductive toxicity (developmental toxicity)
Sub-chronic toxicity
20/10/2010
20/10/2010
20/10/2010
06/12/2010
06/12/2010
06/12/2010
Details
A mixture of: esters of C14-C15 branched alcohols with 3,5-di-t-butyl-4-hydroxyphenyl propionic acid; C15 branched and linear alkyl 3,5-bis(1,1-dimethylethyl)-4-hydroxybenzenepropanoate; C13 branched and linear alkyl 3,5-bis(1,1-dimethylethyl)-4-hydroxybenzenepropanoate 413-750-2 - Reproductive toxicity (pre-natal developmental toxicity) 30/09/2021 15/11/2021 Details
A mixture of: tetrasodium-phosphonoethane-1,2-dicarboxylate,hexasodium-phosphonobutane-1,2,3,4-tetracarboxylate 410-800-5 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
06/03/2012
06/03/2012
20/04/2012
20/04/2012
Details
A mixture of: triphenylthiophosphate and tertiary butylated phenyl derivatives 421-820-9 192268-65-8 Long-term toxicity to fish||Note: testing proposed with O,O,O-triphenyl phosphorothioate (EC no. 209-909-9) 04/12/2023 18/01/2024 Details
A mixture of: α-3-(3-(2H-benzotriazol-2-yl)-5-tert-butyl-4-hydroxyphenyl)propionyl-ω-hydroxypoly(oxyethylene),α-3-(3-(2H-benzotriazol-2-yl)-5-tert-butyl-4-hydroxyphenyl)propionyl-ω-3-(3-(2H-benzotriazol-2-yl)-5-tert-butyl-4-hydroxyphenyl)propionyloxypoly(oxyethylene) 400-830-7 - Reproductive toxicity (pre-natal developmental toxicity) 16/12/2011 30/01/2012 Details
a,a-dimethylphenethyl acetate 205-781-3 151-05-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/05/2017
17/05/2017
03/07/2017
03/07/2017
Details
a,a-dimethylphenethyl butyrate 233-221-8 10094-34-5
Reproductive toxicity (pre-natal developmental toxicity)“|| Note: testing proposed 1,1-Dimethyl-2-phenylethyl acetate (EC 205-781-3)”
Sub-chronic toxicity (90-day): oral“|| Note: testing proposed 1,1-Dimethyl-2-phenylethyl acetate (EC 205-781-3)”
22/11/2017
22/11/2017
08/01/2018
08/01/2018
Details
Acetalization products between glucose and C16-18(even numbered)- alcohol 927-870-2 - Sub-chronic toxicity (90-day): oral 15/09/2011 31/10/2011 Details
Acetalization products between glucose and C20-22(even numbered)- alcohol 923-835-0 - Sub-chronic toxicity (90-day): oral 15/09/2011 31/10/2011 Details
Acetic acid, chloro-, sodium salt, reaction products with 4,5-dihydro-2-undecyl-1H-imidazole-1-ethanol and sodium hydroxide 271-794-6 68608-66-2 Long-term toxicity to fish 18/02/2014 04/04/2014 Details
Acetic acid, chloro-, sodium salt, reaction products with 4,5-dihydro-2-undecyl-1H-imidazole-1-ethanol and sodium hydroxide 271-794-6 68608-66-2 Long-term toxicity to fish Sub-chronic toxicity (90-day): oral || Note: testing proposed with Reaction products of 1H-Imidazole- 1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid (EC 931-291-0) Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid (EC 931-291-0 29/02/2016 14/04/2016 Details
Acetic acid, chloro-, sodium salt, reaction products with 4,5-dihydro-2-undecyl-1H-imidazole-1-ethanol and sodium hydroxide 271-794-6 68608-66-2
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Alkylamidoamine glycinate majority C12, 14 (amphoacetate) EC 931-291-0 || Note: Testing proposal is based on concern identified by the registrant
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Alkylamidoamine glycinate majority C12, 14 (amphoacetate) EC 931-291-0. || Note: Testing proposal is based on concern identified by the registrant
19/10/2020
19/10/2020
03/12/2020
03/12/2020
Details
Activated Carbon - High Density Skeleton 931-328-0 - Sub-chronic toxicity (90 day): inhalation 16/06/2011 01/08/2011 Details
Addition products of m-phenylenebis(methylamine) with reaction mass of 2-(2-(2-butoxyethoxy)ethoxy)ethyl 5-isocyanato-2-methylphenylcarbamate, 2-(2-(2-butoxyethoxy)ethoxy)ethyl 3-isocyanato-4-methylphenylcarbamate and 2-(2-(2-butoxyethoxy)ethoxy)ethyl 3-isocyanato-2-methylphenylcarbamate - -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity) || Note: Testing proposal is based on potential concern identified by the registrant.
Sub-chronic toxicity (90 day): oral
15/07/2014
15/07/2014
15/07/2014
29/08/2014
29/08/2014
29/08/2014
Details
Adipic acid 204-673-3 124-04-9 Reproductive toxicity (extended one-generation reproductive toxicity study) 18/02/2021 05/04/2021 Details
Adipohydrazide 213-999-5 1071-93-8
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
31/01/2014
31/01/2014
17/03/2014
17/03/2014
Details
Alcohols, C11-14-iso-, C13-rich 271-235-6 68526-86-3 Reproductive toxicity (pre-natal developmental toxicity) 21/12/2021 04/02/2022 Details
Alcohols, C11-14-iso-, C13-rich 271-235-6 68526-86-3 Reproductive toxicity (pre-natal developmental toxicity) 27/05/2019 11/07/2019 Details
ALCOHOLS, C11-14-ISO-, C13-RICH 271-235-6 68526-86-3 Sub-chronic toxicity (90-day): oral 31/05/2016 15/07/2016 Details
Alcohols, C12-14, ethoxylated 500-213-3 68439-50-9 Reproductive toxicity (extended one-generation reproductive toxicity study) 26/10/2022 12/12/2022 Details
Alcohols, C13-15-branched and linear 287-625-4 85566-16-1 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Isotridecan-1-ol (EC 248-469-2) 16/12/2020 01/02/2021 Details
Alcohols, C13-15-branched and linear 287-625-4 85566-16-1
Long-term toxicity to fish
Reproductive toxicity (extended one-generation reproductive toxicity study)
31/01/2023
31/01/2023
17/03/2023
17/03/2023
Details
Alcohols, C16-18 and C18-unsatd., ethoxylated, sulfates, sodium salts 500-345-1 157627-95-7 Reproductive toxicity (pre-natal developmental toxicity) 30/06/2023 14/08/2023 Details
Alcohols, C18-22, distn. residues 641-136-6 1160164-88-4 Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018 Details
Alcohols, C18-22, distn. residues 641-136-6 -
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2011
15/07/2011
29/08/2011
29/08/2011
Details
Alcohols, C6-8, ethoxylated 800-182-9 1426148-68-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
28/11/2022
28/11/2022
12/01/2023
12/01/2023
Details
ALCOHOLS, C7-9-ISO-, C8-RICH 271-231-4 68526-83-0 Sub-chronic toxicity (90-day): oral 31/05/2016 15/07/2016 Details
Alcohols, C8-10, ethoxylated 615-247-5 71060-57-6
Long-term toxicity to fish
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
22/09/2022
22/09/2022
22/09/2022
07/11/2022
07/11/2022
07/11/2022
Details
Alcohols, lanolin 232-430-1 8027-33-6
Bioaccumulation aquatic / sediment
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
Details
Alkane 6 438-390-3 -
Reproductive toxicity (extended one-generation reproductive toxicity study || Note: testing proposed with Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1), 1-decene, dimer (EC 917-709-4) and 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 1-Dodecene, Dimer (EC 814-509-8), 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) and Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with 1-Dodecene, dimer, hydrogenated (EC 604-768-3) and 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9)
26/08/2021
26/08/2021
26/08/2021
11/10/2021
11/10/2021
11/10/2021
Details
Alkane-alpha,omega-diyl bis{[(trimethoxysilyl)propyl]carbamate}_M2 700-904-1 1350725-68-6 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Methyl [3-(trimethoxysilyl) propyl]carbamate CAS 23432-62-4 02/11/2018 17/12/2018 Details
Alkanes, C10-13, chloro (Short Chain Chlorinated Paraffins) 287-476-5 85535-84-8 Reproductive toxicity (two-generation reproductive toxicity) 29/07/2011 12/09/2011 Details
Alkanes, C10-13-iso- 271-366-9 68551-17-7 Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Alkanes, C12-14-iso- 271-369-5 68551-19-9
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Hydrocarbons, C7-C9, isoalkanes (EC 921-728-3) || Note: testing proposed with Isohexadecane 2,2,4,4,6,8,8-heptamethylnonane (EC 224-506-8)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Hydrocarbons, C7-C9, isoalkanes (EC 921-728-3) || Note: testing proposed with Isohexadecane 2,2,4,4,6,8,8-heptamethylnonane (EC 224-506-8)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Hydrocarbons, C7-C9, isoalkanes (EC 921-728-3) || Note: testing proposed with Isohexadecane 2,2,4,4,6,8,8-heptamethylnonane (EC 224-506-8)
23/11/2020
23/11/2020
23/11/2020
07/01/2021
07/01/2021
07/01/2021
Details
Alkanes, C12-26-branched and linear 292-454-3 90622-53-0 Reproductive toxicity (two-generation reproductive toxicity) 15/09/2011 31/10/2011 Details
Alkanoic acid and polyoxomolybdate borate alkanoate clusters 944-813-7 - Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 24/08/2020 08/10/2020 Details
Alkenes C20+ 931-467-7 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/09/2011
15/09/2011
31/10/2011
31/10/2011
Details
Alkenes, C10-13 287-479-1 85535-87-1
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/09/2011
15/09/2011
31/10/2011
31/10/2011
Details
Alkenes, C10-14 288-213-7 85681-75-0
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/09/2011
15/09/2011
25/06/2012
31/10/2011
31/10/2011
09/08/2012
Details
Alkenes, C11-12 931-515-7 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
03/11/2011
03/11/2011
25/06/2012
19/12/2011
19/12/2011
09/08/2012
Details
Alkenes, C11-12, hydroformylation products, distn. Residues 292-427-6 90622-27-8 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018 Details
Alkenes, C11-12, hydroformylation products, distn. residues 292-427-6 90622-27-8
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/09/2011
15/09/2011
15/09/2011
31/10/2011
31/10/2011
31/10/2011
Details
Alkenes, C11-12, hydroformylation products, low boiling 932-235-8 - Reproductive toxicity (two-generation reproductive toxicity) 16/06/2011 01/08/2011 Details
Alkenes, C13-14 931-071-4 - Sub-chronic toxicity (90-day): oral 25/06/2012 09/08/2012 Details
Alkenes, C13-14 - -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
29/07/2011
29/07/2011
12/09/2011
12/09/2011
Details