Korábbi/eredmények

Korábbi/eredmények

Korábbi/eredmények

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

There are currently no ongoing consultations.
 
Reaction mass of Ammonium bisethanedioato bisaquo niobate(V) (anhydrous form) and Ammonium hydrogen ethanedioate ethanedioic acid (anhydrous form 939-559-9 - Reproductive toxicity (pre-natal developmental toxicity) 01/09/2017 16/10/2017 Details
Reaction mass of benzyl 2-ethylhexyl adipate and bis(2-ethylhexyl) adipate and dibenzyl adipate 905-983-8 - Reproductive toxicity (pre-natal developmental toxicity) 14/08/2014 28/09/2014 Details
Reaction mass of diisobutyl hydrogen phosphate and isobutyl dihydrogen phosphate 911-351-2 - Reproductive toxicity (pre-natal developmental toxicity) 14/08/2014 28/09/2014 Details
Reaction mass of Poly(oxy-1,2-ethanediyl), ?-[2-[(2-hydroxyethyl)amino]-2-oxoethyl]-?-hydroxy-, mono-C13-15-alkyl ethers (odd numbered, branched and linear)-alkylethers, Acetamide, 2-(C13-15 (odd numbered, branched and linear)-alkyloxy)-N-(2-hydroxyethyl)- and Alcohols, C13-15-branched and linear - - Reproductive toxicity (pre-natal developmental toxicity) 16/08/2011 30/09/2011 Details
Reaction mass of potassium ethyl octylphosphonate and diethyl octylphosphonate 939-595-5 - Reproductive toxicity (pre-natal developmental toxicity) 17/04/2015 04/06/2015 Details
Reaction mass of sodium hydrogen N-(1-oxooctadecyl)-L-glutamate and stearic acid 939-201-1 - Reproductive toxicity (pre-natal developmental toxicity) 25/06/2015 10/08/2015 Details
reaction mass of: 2-(2-((oxo(phenyl)acetyl)oxy)ethoxy)ethyl oxo(phenyl)acetate (2-(2-hydroxyethoxy)ethyl) oxo(phenyl)acetate 442-300-8 - Reproductive toxicity (pre-natal developmental toxicity) 15/01/2013 01/03/2013 Details
reaction mass of: triphenylthiophosphate and tertiary butylated phenyl derivatives 421-820-9 192268-65-8 Reproductive toxicity (pre-natal developmental toxicity) 16/10/2014 01/12/2014 Details
Reaction product of Crude sludge and Calcium oxide. Crude sludge is the mixture of by-products of petroleum hydrocarbons refining (especially Total petroleum hydrocarbons, Polycyclic aromatic hydrocarbons, acid-refined heavy petroleum distillates). The Crude sludge is neutralised by calcium oxide in the ratio 80:20. The maturing process proceeds under ambient conditions and takes for at least 3 days. Subsequently, the reaction product is processed mechanically 930-592-4 - Reproductive toxicity (pre-natal developmental toxicity) 20/09/2013 04/11/2013 Details
Reaction product of Distillates (petroleum), acid-treated heavy naphthenic and calcium oxide - - Reproductive toxicity (pre-natal developmental toxicity) 16/08/2011 30/09/2011 Details
Reaction products of 5,5-dimethylhydantoin and ethylene oxide 701-388-0 - Reproductive toxicity (pre-natal developmental toxicity) 25/11/2021 10/01/2022 Details
Reaction Products of alcohols, C14-18, C18 unsat., esterified with phosphorus pentoxide and salted with amines, C12-14,-tert-alkyl 939-591-3 - Reproductive toxicity (pre-natal developmental toxicity) 15/04/2014 30/05/2014 Details
Reaction products of Fatty acids, C16-18 and C18-unsatd. and reaction mass of 1,3-alkanediol, 2-(hydroxymethyl)-2-[(methoxymethoxy)methyl]- and 1,3-heteromonocycle-5,5-dimethanol 484-360-8 98859-60-0 Reproductive toxicity (pre-natal developmental toxicity) 17/08/2012 01/10/2012 Details
Renewable hydrocarbons (diesel type fraction) 618-882-6 928771-01-1 Reproductive toxicity (pre-natal developmental toxicity) 01/09/2017 16/10/2017 Details
Resin acids and Rosin acids, calcium salts 232-694-8 9007-13-0 Reproductive toxicity (pre-natal developmental toxicity) 06/03/2012 20/04/2012 Details
Resin acids and Rosin acids, calcium zinc salts 269-825-3 68334-35-0 Reproductive toxicity (pre-natal developmental toxicity) 06/03/2012 20/04/2012 Details
Resin acids and Rosin acids, esters with glycerol 232-482-5 8050-31-5 Reproductive toxicity (pre-natal developmental toxicity) 06/03/2012 20/04/2012 Details
Resin acids and Rosin acids, esters with triethylene glycol 232-478-3 8050-25-7 Reproductive toxicity (pre-natal developmental toxicity) 06/03/2012 20/04/2012 Details
Resin acids and Rosin acids, fumarated, esters with pentaerythritol 305-514-1 94581-15-4 Reproductive toxicity (pre-natal developmental toxicity) 16/07/2012 30/08/2012 Details
Resin acids and Rosin acids, hydrogenated, esters with glycerol 266-042-9 65997-13-9 Reproductive toxicity (pre-natal developmental toxicity) 06/03/2012 20/04/2012 Details
Resin acids and Rosin acids, hydrogenated, esters with pentaerythritol 264-848-5 64365-17-9 Reproductive toxicity (pre-natal developmental toxicity) 06/03/2012 20/04/2012 Details
Resin acids and Rosin acids, magnesium salts 270-461-2 68440-56-2 Reproductive toxicity (pre-natal developmental toxicity) 06/03/2012 20/04/2012 Details
Resin acids and Rosin acids, potassium salts 263-142-4 61790-50-9 Reproductive toxicity (pre-natal developmental toxicity) 06/03/2012 20/04/2012 Details
Resin acids and Rosin acids, sodium salts 263-144-5 61790-51-0 Reproductive toxicity (pre-natal developmental toxicity) 06/03/2012 20/04/2012 Details
Rosin, fumarated, reaction products with formaldehyde 305-795-0 95009-65-7 Reproductive toxicity (pre-natal developmental toxicity) 06/03/2012 20/04/2012 Details
Rosin, fumarated, reaction products with glycerol and pentaerythritol 296-047-1 92202-14-7 Reproductive toxicity (pre-natal developmental toxicity) 16/07/2012 30/08/2012 Details
Rosin, hydrogenated 266-041-3 65997-06-0 Reproductive toxicity (pre-natal developmental toxicity) 06/03/2012 20/04/2012 Details
Rosin, maleated 232-480-4 8050-28-0 Reproductive toxicity (pre-natal developmental toxicity) 06/03/2012 20/04/2012 Details
Rosin, reaction products with formaldehyde 293-659-0 91081-53-7 Reproductive toxicity (pre-natal developmental toxicity) 06/03/2012 20/04/2012 Details
Slags, ferromanganese-manufg. 273-728-1 69012-28-8 Reproductive toxicity (pre-natal developmental toxicity) 26/03/2018 11/05/2018 Details
Sodium 2-[(2-aminoethyl)amino]ethanesulphonate 252-173-9 34730-59-1 Reproductive toxicity (pre-natal developmental toxicity) 29/04/2014 13/06/2014 Details
Sodium chloroacetate 223-498-3 3926-62-3 Reproductive toxicity (pre-natal developmental toxicity) 14/10/2011 28/11/2011 Details
Sodium hydroxymethanesulphinate 205-739-4 149-44-0 Reproductive toxicity (pre-natal developmental toxicity) 27/05/2019 11/07/2019 Details
Sodium N-(2-carboxyethyl)-N-(2-ethylhexyl)-β-alaninate 305-318-6 94441-92-6 Reproductive toxicity (pre-natal developmental toxicity) 02/06/2014 17/07/2014 Details
Sodium N-lauroylsarcosinate 205-281-5 137-16-6 Reproductive toxicity (pre-natal developmental toxicity) 25/06/2015 10/08/2015 Details
Sodium p-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]benzenesulphonate 223-989-2 4156-21-2 Reproductive toxicity (pre-natal developmental toxicity) 03/04/2023 22/05/2023 Details
Sodium permanganate 233-251-1 10101-50-5 Reproductive toxicity (pre-natal developmental toxicity) 15/04/2011 30/05/2011 Details
Sodium trichloroacetate, TCA 211-479-2 650-51-1 Reproductive toxicity (pre-natal developmental toxicity) 14/10/2011 28/11/2011 Details
sodium/triethanolamine 4-((2-hydroxyethyl)amino)-3-pentaproenyl-4-oxobutanoate 800-765-8 1424149-03-0 Reproductive toxicity (pre-natal developmental toxicity) 15/07/2014 29/08/2014 Details
Soybean oil, oligomerized 701-252-0 - Reproductive toxicity (pre-natal developmental toxicity) 06/09/2018 22/10/2018 Details
Strontium oxide 215-219-9 1314-11-0 Reproductive toxicity (pre-natal developmental toxicity) 25/06/2019 09/08/2019 Details
Sulfonium compounds, C11-14-alkylbis(hydroxyethyl), 2-hydroxyethyl sulfates (salts) 278-855-6 78169-20-7 Reproductive toxicity (pre-natal developmental toxicity) 18/02/2014 04/04/2014 Details
Sulphamidic acid 226-218-8 5329-14-6 Reproductive toxicity (pre-natal developmental toxicity) 25/11/2021 10/01/2022 Details
Tar, wood 294-436-0 91722-33-7 Reproductive toxicity (pre-natal developmental toxicity) 23/02/2022 12/04/2022 Details
Terephthalic acid 202-830-0 100-21-0 Reproductive toxicity (pre-natal developmental toxicity) 16/12/2020 01/02/2021 Details
Terpenes and terpenoids, turpentine-oil, α-pinene fraction, oligomers. 500-245-8 70750-57-1 Reproductive toxicity (pre-natal developmental toxicity) 04/04/2014 19/05/2014 Details
terpenic oligomers - - Reproductive toxicity (pre-natal developmental toxicity) 26/10/2022 12/12/2022 Details
tert-butyl peroxypivalate 213-147-2 927-07-1 Reproductive toxicity (pre-natal developmental toxicity) 21/03/2014 05/05/2014 Details
Tetrasodium 7,7'-(carbonyldiimino)bis[4-hydroxy-3-[(6-sulphonato-2-naphthyl)azo]naphthalene-2-sulphonate] 249-171-5 28706-25-4 Reproductive toxicity (pre-natal developmental toxicity) 10/05/2022 27/06/2022 Details
Trichloroacetic acid 200-927-2 76-03-9 Reproductive toxicity (pre-natal developmental toxicity) 14/10/2011 28/11/2011 Details
Trimethoxyphenylsilane 221-066-9 2996-92-1 Reproductive toxicity (pre-natal developmental toxicity) 03/03/2014 17/04/2014 Details
Tris(2,4-ditert-butylphenyl) phosphite 250-709-6 31570-04-4 Reproductive toxicity (pre-natal developmental toxicity) 28/11/2022 12/01/2023 Details
tris(2-methoxyethoxy)vinylsilane 213-934-0 1067-53-4 Reproductive toxicity (pre-natal developmental toxicity) 29/07/2011 12/09/2011 Details
Tris({[(hydroxyalkyl)amino]oxy}-oxoalkyl)-triazaalkanoic acid and water - - Reproductive toxicity (pre-natal developmental toxicity) 12/06/2013 29/07/2013 Details
Tris[4-(diethylamino)phenyl]methylium acetate 263-974-8 63157-72-2 Reproductive toxicity (pre-natal developmental toxicity) 15/07/2011 29/08/2011 Details
Vinylene carbonate 212-825-5 872-36-6 Reproductive toxicity (pre-natal developmental toxicity) 25/11/2021 10/01/2022 Details
Yttrium zirconium oxide 264-885-7 64417-98-7 Reproductive toxicity (pre-natal developmental toxicity) 29/04/2014 13/06/2014 Details
Zirconium dioxide 215-227-2 1314-23-4 Reproductive toxicity (pre-natal developmental toxicity) 15/04/2011 30/05/2011 Details
δ-valerolactone 208-807-1 542-28-9 Reproductive toxicity (pre-natal developmental toxicity) 14/08/2014 28/09/2014 Details
Bis(trimethoxysilylpropyl)amine 280-084-5 82985-35-1
Reproductive toxicity (pre-natal developmental toxicity
Sub-chronic toxicity (90-day): oral
17/06/2020
17/06/2020
03/08/2020
03/08/2020
Details
Ditetradecyl peroxydicarbonate 258-436-4 53220-22-7
Reproductive toxicity (pre-natal developmental toxicity
Sub-chronic toxicity (90-day): oral
31/01/2018
31/01/2018
19/03/2018
19/03/2018
Details
Poly(oxy-1,2-ethanediyl), .alpha.-[3-[(carboxymethyl)methylamino]-2-hydroxypropyl]-.omega.-(4-nonylphenoxy)-, monosodium sal 616-248-3 75627-31-5
Reproductive toxicity (pre-natal developmental toxicity
Sub-chronic toxicity (90-day): oral
23/12/2015
23/12/2015
03/02/2016
03/02/2016
Details
Resin acids and Rosin acids, calcium salts 232-694-8 9007-13-0
Reproductive toxicity (pre-natal developmental toxicity || Note: Testing proposed with Rosin CAS 8050-09-7
Reproductive toxicity (two-generation reproductive toxicity) || Note: Testing proposed with Rosin CAS 8050-09-7
Sub-chronic toxicity (90-day): oral || Note: Testing proposed with Rosin CAS 8050-09-7, Rosin hydrogenated CAS 65997-06-0, and Rosin reaction products with formaldehyde CAS 91081-53-7
02/07/2013
02/07/2013
02/07/2013
16/08/2013
16/08/2013
16/08/2013
Details
2,2-bis(hydroxymethyl)propionic acid // 3-hydroxy-2-(hydroxymethyl)-2-methylpropanoic acid 225-306-3 -
Reproductive toxicity (pre-natal developmental toxicity study)
Sub-chronic oral toxicity (90-day): oral
05/04/2011
05/04/2011
20/05/2011
20/05/2011
Details
Bis(α,α-dimethylbenzyl) peroxide 201-279-3 80-43-3 Reproductive toxicity (pre-natal developmental toxicity 20/10/2016 05/12/2016 Details
2-methylpropane-2-thiol 200-890-2 75-66-1
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with tert-dodecanethiol (EC no. 246-619-1 )
Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with tert-dodecanethiol (EC no. 246-619-1)
22/09/2022
22/09/2022
07/11/2022
07/11/2022
Details
[[(phosphonomethyl)imino]bis[ethylenenitrilobis(methylene)]]tetrakisphosphonic acid, ammonium salt 274-798-6 70714-66-8 Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Sodium salts of [[(phosphonomethyl)imino]bis[ethane-2,1-diylnitrilobis(methylene)]]tetrakisphosphonic acid (5-7 Na:1) (EC no. 701-216-4) 01/03/2023 17/04/2023 Details
Divanadium tris(sulphate) 237-226-6 13701-70-7
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Sodium metavanadate (EC no. 237-272-7)
Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Sodium metavanadate (EC no. 237-272-7)
30/06/2023
30/06/2023
14/08/2023
14/08/2023
Details
Xylene 215-535-7 1330-20-7 Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Reaction mass of ethylbenzene and xylene (EC no. 905-588-0) 31/01/2023 17/03/2023 Details
Xylene 215-535-7 1330-20-7 Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Reaction mass of ethylbenzene and xylene (EC No 905-588-0) 01/03/2023 17/04/2023 Details
Hydrocarbons, C4, steam-cracker distillate 295-405-4 92045-23-3
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC no. 306-004-1)
Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC no. 306-004-1)
Sub-chronic toxicity (90 day): inhalation||Note: testing proposed with Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC no. 306-004-1)
06/06/2023
06/06/2023
06/06/2023
21/07/2023
21/07/2023
21/07/2023
Details
Petroleum diesel/gas oil fraction, co-processed with renewable hydrocarbons derived from thermally cracked plastics 941-803-4 -
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Gas oils (petroleum), light vacuum (EC no. 265-059-9)
Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Gas oils (petroleum), light vacuum (EC no. 265-059-9) ||Note: testing proposed with Fuels, diesel (EC no. 269-822-7) ||Note: testing proposed with Fuel oil, no. 4 (EC no. 270-673-5) ||Note: testing proposed with Distillates (petroleum), light hydrocracked (EC no. 265-078-2)
Sub-chronic toxicity (90-day): oral||Note: testing proposed with Gas oils (petroleum), light vacuum (EC no. 265-059-9)
26/10/2022
26/10/2022
26/10/2022
12/12/2022
12/12/2022
12/12/2022
Details
Extracts (petroleum), deasphalted vacuum residue solvent 295-332-8 91995-70-9 Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Extracts (petroleum), residual oil solvent (EC no. 265-110-5) 06/06/2023 21/07/2023 Details
Dodecene, branched 306-479-5 97280-83-6
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Butene, homopolymer (products derived from either/or But-1-ene/But-2-ene), branched (EC no. 500-004-7)
Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Butene, homopolymer (products derived from either/or But-1-ene/But-2-ene), branched (EC no. 500-004-7)
Sub-chronic toxicity (90-day): oral||Note: testing proposed with Butene, homopolymer (products derived from either/or But-1-ene/But-2-ene), branched (EC no. 500-004-7)
06/06/2023
06/06/2023
06/06/2023
21/07/2023
21/07/2023
21/07/2023
Details
Hydrocarbons, C4, 1,3-butadiene-free, polymd., triisobutylene fraction 293-263-8 91053-01-9
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Butene, homopolymer (products derived from either/or But-1-ene/But-2-ene) (EC no. 500-004-7)
Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Butene, homopolymer (products derived from either/or But-1-ene/But-2-ene) (EC no. 500-004-7)
Sub-chronic toxicity (90-day): oral||Note: testing proposed with Butene, homopolymer (products derived from either/or But-1-ene/But-2-ene) (EC no. 500-004-7)
06/06/2023
06/06/2023
06/06/2023
21/07/2023
21/07/2023
21/07/2023
Details
4-[[4-(aminocarbonyl)phenyl]azo]-N-(2-ethoxyphenyl)-3-hydroxynaphthalene-2-carboxamide – nano form 220-509-3 2786-76-7 Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with [3-hydroxy-N-(o-tolyl)-4-[(2,4,5-trichlorophenyl)azo]naphthalene-2-carboxamide] (EC no. 229-440-3) 03/10/2023 17/11/2023 Details
4,4'-Methylenediphenyl diisocyanate, oligomeric reaction products with 2,4'-diisocyanatodiphenylmethane 500-297-1 109331-54-6 Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0) 31/01/2023 17/03/2023 Details
2-butene 203-452-9 107-01-7
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with 2-methylpropene (EC no. 204-066-3)
Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with 2-methylpropene (EC no. 204-066-3)
Sub-chronic toxicity (90 day): inhalation||Note: testing proposed with 2-methylpropene (EC no. 204-066-3)
06/06/2023
06/06/2023
06/06/2023
21/07/2023
21/07/2023
21/07/2023
Details
But-1-ene 203-449-2 106-98-9
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with 2-methylpropene (EC no. 204-066-3)
Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with 2-methylpropene (EC no. 204-066-3)
Sub-chronic toxicity (90 day): inhalation||Note: testing proposed with 2-methylpropene (EC no. 204-066-3)
06/06/2023
06/06/2023
06/06/2023
21/07/2023
21/07/2023
21/07/2023
Details
Butene 246-689-3 25167-67-3
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with 2-methylpropene (EC no. 204-066-3)
Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with 2-methylpropene (EC no. 204-066-3)
Sub-chronic toxicity (90 day): inhalation||Note: testing proposed with 2-methylpropene (EC no. 204-066-3)
06/06/2023
06/06/2023
06/06/2023
21/07/2023
21/07/2023
21/07/2023
Details
Ethylenediamine, propoxylated 500-035-6 25214-63-5
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with 1,1',1'',1'''-ethylenedinitrilotetrapropan-2-ol (EC no. 203-041-4)
Reproductive toxicity (pre-natal developmental toxicity)
22/09/2022
22/09/2022
07/11/2022
07/11/2022
Details
N'-[3-(dimethylamino)propyl]-N,N-dimethylpropane-1,3-diamine 229-761-9 6711-48-4 Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with N,N-diethylpropane-1,3-diamine (EC no. 203-236-4) 22/09/2022 07/11/2022 Details
Sodium N-lauroylsarcosinate 205-281-5 137-16-6 Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: Note: testing proposed with N-methyl-N-[C18-(unsaturated)alkanoyl]glycine (EC no. 701-177-3) 30/06/2023 14/08/2023 Details
Vanadium dioxide 234-841-1 12036-21-4
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: : testing proposed with Sodium metavanadate (EC no. 237-272-7)
Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Sodium metavanadate (EC no. 237-272-7)
16/06/2022
16/06/2022
01/08/2022
01/08/2022
Details
Divanadium pentaoxide 215-239-8 1314-62-1
Reproductive toxicity (extended one-generation reproductive toxicity study)|| Note: testing proposed with sodium metavanadate (EC no. 237-272-7)
Reproductive toxicity (pre-natal developmental toxicity)|| Note: testing proposed with sodium metavanadate (EC no. 237-272-7)
10/05/2022
10/05/2022
27/06/2022
27/06/2022
Details
1,4-bis(2,3-epoxypropoxy)butane 219-371-7 2425-79-8 Reproductive toxicity (extended one-generation reproductive toxicity study)|| Note: testing proposed with Reaction products of hexane-1,6-diol with 2-(chloromethyl)oxirane (1:2) (EC 618-939-5) 23/03/2020 07/05/2020 Details
1,1,1,3,3,3-hexamethyldisilazane 213-668-5 999-97-3
Reproductive toxicity (extended one-generation reproductive toxicity study)|| Note: testing proposed with Hydroxytrimethylsilane (EC no. 213-914-1)
Reproductive toxicity (pre-natal developmental toxicity)|| Note: testing proposed with Hydroxytrimethylsilane (EC no. 213-914-1)
16/06/2022
16/06/2022
01/08/2022
01/08/2022
Details
4,4'-methylenediphenyl diisocyanate and its oligomeric reaction products with oxydipropanol and [(methylethylene)bis(oxy)]dipropanol 701-072-2 - Reproductive toxicity (extended one-generation reproductive toxicity study)|| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no: 202-966-0) 16/06/2022 01/08/2022 Details
1,1'-Methylenebis(4-isocyanatobenzene) and 1,1'-methylenebis(4-isocyanatobenzene) homopolymer and their reaction products with [(methylethylene)bis(oxy)]dipropanol and butane-1,3-diol and propane-1,2-diol 701-393-8 - Reproductive toxicity (extended one-generation reproductive toxicity study)|| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0) 16/06/2022 01/08/2022 Details
Reaction mass of 4,4'-methylenediphenyl diisocyanate and o-(p-isocyanatobenzyl)phenyl isocyanate / methylene diphenyl diisocyanate 905-806-4 - Reproductive toxicity (extended one-generation reproductive toxicity study)|| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0) 16/06/2022 01/08/2022 Details
4,4'-Methylenediphenyl diisocyanate, oligomers 500-040-3 25686-28-6 Reproductive toxicity (extended one-generation reproductive toxicity study)|| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0) 16/06/2022 01/08/2022 Details
COBALT DICHLORIDE 231-589-4 7646-79-9
Reproductive toxicity (extended one-generation reproductive toxicity study)

Reproductive toxicity (pre-natal developmental toxicity)
29/04/2016
29/04/2016
13/06/2016
13/06/2016
Details
Reaction products of monoethanolamine and boric acid (1:1) 701-025-6 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Reaction products of monoethanolamine and boric acid (1:3) (EC 701-024-0)
Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Reaction products of monoethanolamine and boric acid (1:3) (EC 701-024-0)
Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with Reaction products of monoethanolamine and boric acid (1:3) (EC 701-024-0)
27/01/2020
27/01/2020
27/01/2020
12/03/2020
12/03/2020
12/03/2020
Details
Poly(oxy-1,2-ethanediyl), α-butyl-ω-hydroxy- 500-012-0 9004-77-7
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with 2-(2-(2-methoxyethoxy)ethoxy)ethanol (EC 203-962-1).
Reproductive toxicity (pre-natal developmental toxicity) – rabbits
|| Note: testing proposed with 2-(2-(2-butoxyethoxy)ethoxy)ethanol (EC 205-592-6)
Reproductive toxicity (pre-natal developmental toxicity) – rats-
|| Note: testing proposed with 2-(2-(2-butoxyethoxy)ethoxy)ethanol (EC 205-592-6)
27/01/2020
27/01/2020
27/01/2020
12/03/2020
12/03/2020
12/03/2020
Details
1,3-dimethylimidazolidin-2-one 201-304-8 80-73-9
Reproductive toxicity (extended one-generation reproductive toxicity study)
Sub-chronic toxicity (90-day): oral
10/05/2022
10/05/2022
27/06/2022
27/06/2022
Details
2-ethyl-2-[[(1-oxoallyl)oxy]methyl]-1,3-propanediyl diacrylate; 2,2-bis(acryloyloxymethyl)butyl acrylate; trimethylolpropane triacrylate 239-701-3 15625-89-5
Reproductive toxicity (extended one-generation reproductive toxicity study)
Sub-chronic toxicity (90-day): oral
25/05/2020
25/05/2020
09/07/2020
09/07/2020
Details
Carboxymethyldimethyl-3-[[(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)sulphonyl]amino]propylammonium hydroxide 252-046-8 34455-29-3
Reproductive toxicity (extended one-generation reproductive toxicity study)
Sub-chronic toxicity (90-day): oral
16/12/2020
16/12/2020
01/02/2021
01/02/2021
Details
Nonane-1,9-diol 223-517-5 3937-56-2
Reproductive toxicity (extended one-generation reproductive toxicity study)
Sub-chronic toxicity (90-day): oral
05/07/2018
05/07/2018
20/08/2018
20/08/2018
Details
Nonane-1,9-diol 223-517-5 3937-56-2
Reproductive toxicity (extended one-generation reproductive toxicity study)
Sub-chronic toxicity (90-day): oral
16/12/2020
16/12/2020
01/02/2021
01/02/2021
Details
N-methylaniline 202-870-9 100-61-8
Reproductive toxicity (extended one-generation reproductive toxicity study)
Sub-chronic toxicity (90 day): dermal
23/04/2018
23/04/2018
07/06/2018
07/06/2018
Details
Propene 204-062-1 115-07-1
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with ethylene (EC no. 200-815-3)
10/05/2022
10/05/2022
27/06/2022
27/06/2022
Details
Reaction mass of Octadecanamide, 12-hydroxy-N-[2-[(1-oxodecyl)amino]ethyl]- and N,N'-ethane-1,2-diylbis(12-hydroxyoctadecan-1-amide) and Decanamide, N,N'-1,2-ethanediylbis- 907-495-0 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity): in rat and rabbit
Sub-chronic toxicity (90 day): inhalation
27/05/2019
27/05/2019
27/05/2019
11/07/2019
11/07/2019
11/07/2019
Details
1,4-diazabicyclooctane 205-999-9 280-57-9
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
26/10/2022
26/10/2022
26/10/2022
12/12/2022
12/12/2022
12/12/2022
Details
1-(2-hydroxyethyl)pyrrolidin-2-one 222-359-4 3445-11-2
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/12/2020
16/12/2020
16/12/2020
01/02/2021
01/02/2021
01/02/2021
Details
2,2',6,6'-Tetrabromo-4,4'-isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane 500-107-7 40039-93-8
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
27/09/2017
27/09/2017
27/09/2017
13/11/2017
13/11/2017
13/11/2017
Details
3,6-bis(4-chlorophenyl)-1H,2H,4H,5H-pyrrolo[3,4-c]pyrrole-1,4-dione 401-540-3 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
26/03/2018
26/03/2018
26/03/2018
11/05/2018
11/05/2018
11/05/2018
Details
4,4'-Isopropylidenediphenol, ethoxylated 500-082-2 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
21/05/2018
21/05/2018
21/05/2018
05/07/2018
05/07/2018
05/07/2018
Details
Benzyldimethylamine 203-149-1 103-83-3
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
23/03/2020
23/03/2020
23/03/2020
07/05/2020
07/05/2020
07/05/2020
Details
Butene, homopolymer (products derived from either/or But-1-ene/But-2-ene) 500-004-7 9003-29-6
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
06/06/2023
06/06/2023
06/06/2023
21/07/2023
21/07/2023
21/07/2023
Details
C16-(branched), C20-(branched) and C24-(branched)-alkanes 700-992-1 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
28/02/2018
28/02/2018
28/02/2018
16/04/2018
16/04/2018
16/04/2018
Details
Di-tert-butyl trisulphide 224-226-6 4253-90-1
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
01/03/2023
01/03/2023
01/03/2023
17/04/2023
17/04/2023
17/04/2023
Details
Dibenzoyl peroxide 202-327-6 94-36-0
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/12/2020
16/12/2020
16/12/2020
01/02/2021
01/02/2021
01/02/2021
Details
Ethane- 1,2-diol, propoxylated 500-078-0 31923-84-9
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
05/07/2018
05/07/2018
05/07/2018
20/08/2018
20/08/2018
20/08/2018
Details
Fatty acids, C12-14 (even numbered), methyl ester 629-776-4 308065-15-8
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
30/09/2021
30/09/2021
30/09/2021
15/11/2021
15/11/2021
15/11/2021
Details
Hexadecane 208-878-9 544-76-3
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
21/01/2021
21/01/2021
21/01/2021
08/03/2021
08/03/2021
08/03/2021
Details
Hydrocarbons, C10-C13, aromatics, 922-153-0 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
21/01/2021
21/01/2021
21/01/2021
08/03/2021
08/03/2021
08/03/2021
Details
Hydrocarbons, C10-C13, n-alkanes, isoalkanes, cyclics, aromatics (2-25%) 919-164-8 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
21/01/2021
21/01/2021
21/01/2021
08/03/2021
08/03/2021
08/03/2021
Details
Hydrocarbons, C14-C19, isoalkanes, cyclics, <2% aromatics 920-114-2 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
21/01/2021
21/01/2021
21/01/2021
08/03/2021
08/03/2021
08/03/2021
Details
Hydrocarbons, C16-C20, n-alkanes, isoalkanes, cyclics, aromatics (2-30 %) 919-006-8 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
21/01/2021
21/01/2021
21/01/2021
08/03/2021
08/03/2021
08/03/2021
Details
Hydrocarbons, C7-C9, isoalkanes 921-728-3 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
21/01/2021
21/01/2021
21/01/2021
08/03/2021
08/03/2021
08/03/2021
Details
Hydrocarbons, C9-C10, aromatics, >1% naphthalene 946-365-8 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
21/01/2021
21/01/2021
21/01/2021
08/03/2021
08/03/2021
08/03/2021
Details
Hydrocarbons, C9-C11, isoalkanes, cyclics 920-134-1 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
21/01/2021
21/01/2021
21/01/2021
08/03/2021
08/03/2021
08/03/2021
Details
Isobutyric acid, monoester with 2,2,4-trimethylpentane-1,3-diol 246-771-9 25265-77-4
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
26/04/2019
26/04/2019
26/04/2019
10/06/2019
10/06/2019
10/06/2019
Details
Lithium bis(fluorosulfonyl)imide 686-526-7 171611-11-3
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
21/10/2021
21/10/2021
21/10/2021
07/12/2021
07/12/2021
07/12/2021
Details
Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts 270-608-0 68457-79-4
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
01/09/2016
01/09/2016
01/09/2016
17/10/2016
17/10/2016
17/10/2016
Details
Pivalic acid 200-922-5 75-98-9
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
20/12/2017
20/12/2017
20/12/2017
05/02/2018
05/02/2018
05/02/2018
Details
Pleuromulin 204-747-5 125-65-5
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
06/09/2018
06/09/2018
06/09/2018
22/10/2018
22/10/2018
22/10/2018
Details
Polysulfides, di-tert-dodecyl 270-335-7 68425-15-0
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
31/01/2018
31/01/2018
31/01/2018
19/03/2018
19/03/2018
19/03/2018
Details
Reaction mass of 1-(2,3-epoxypropoxy)-2,2-bis ((2,3-epoxypropoxy)methyl) butane and 1-(2,3-epoxypropoxy)-2-((2,3-epoxypropoxy)methyl)-2-hydroxymethyl butane 608-489-8 30499-70-8
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
25/06/2015
25/06/2015
25/06/2015
10/08/2015
10/08/2015
10/08/2015
Details
Reaction mass of C18 (unsatd.) fatty acid amides/esters of diethanolamine, C16-18 (even-numbered) fatty amine (..) 943-172-0 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/05/2016
17/05/2016
17/05/2016
01/07/2016
01/07/2016
01/07/2016
Details
Reaction products of monoethanolamine and boric acid (1:3) 701-024-0 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
27/01/2020
27/01/2020
27/01/2020
12/03/2020
12/03/2020
12/03/2020
Details
Triethoxyoctylsilane 220-941-2 2943-75-1
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
27/09/2017
27/09/2017
27/09/2017
13/11/2017
13/11/2017
13/11/2017
Details
Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) 230-257-6 6990-43-8
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
21/12/2021
21/12/2021
21/12/2021
04/02/2022
04/02/2022
04/02/2022
Details
1,1'-methylenebis(4-isocyanatobenzene) and oligomeric reaction products of 1,1'-methylenebis(4-isocyanatobenzene) and oxydipropanol and oligomerization reaction products of oxydipropanol 701-041-3 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): inhalation
16/06/2022
16/06/2022
16/06/2022
01/08/2022
01/08/2022
01/08/2022
Details
2-methylpropene 204-066-3 115-11-7
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): inhalation
06/06/2023
06/06/2023
06/06/2023
21/07/2023
21/07/2023
21/07/2023
Details
Hydrocarbons, C4, 1,3-butadiene- and isobutene-free 306-004-1 95465-89-7
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): inhalation
06/06/2023
06/06/2023
06/06/2023
21/07/2023
21/07/2023
21/07/2023
Details
Distillates (petroleum), hydrodesulfurized middle 265-183-3 64742-80-9
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): dermal
28/02/2019
28/02/2019
28/02/2019
15/04/2019
15/04/2019
15/04/2019
Details
Distillates (petroleum), hydrotreated middle 265-148-2 64742-46-7
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): dermal
28/02/2019
28/02/2019
28/02/2019
15/04/2019
15/04/2019
15/04/2019
Details
Extracts (petroleum), deasphalted vacuum residue solvent 295-332-8 91995-70-9
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): dermal
28/02/2019
28/02/2019
28/02/2019
15/04/2019
15/04/2019
15/04/2019
Details
Extracts (petroleum), residual oil solvent 265-110-5 64742-10-5
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): dermal
28/02/2019
28/02/2019
28/02/2019
15/04/2019
15/04/2019
15/04/2019
Details
Gas oils (petroleum), hydrodesulfurized 265-182-8 64742-79-6
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): dermal
28/02/2019
28/02/2019
28/02/2019
15/04/2019
15/04/2019
15/04/2019
Details
2-hydroxy-2-methylpropiophenone 231-272-0 7473-98-5
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90 day)
21/10/2019
15/03/2011
15/03/2011
15/03/2011
05/12/2019
29/04/2011
29/04/2011
29/04/2011
Details
Benzene, 1,1'-oxybis-, tetrapropylene derivatives, sulfonated, sodium salts 601-601-6 119345-04-9
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity) with the Rabbit
27/05/2019
27/05/2019
11/07/2019
11/07/2019
Details
Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts 270-608-0 68457-79-4
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with the substance, with Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with the substance, with Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), and Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5)
21/12/2021
21/12/2021
21/12/2021
04/02/2022
04/02/2022
04/02/2022
Details
(1-methylethylidene)di-4,1-phenylenetetraphenyl diphosphate 425-220-8 5945-33-5
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
26/08/2021
26/08/2021
11/10/2021
11/10/2021
Details
(2E)-2-ethyl-4-(2,2,3-trimethylcyclopent-3-en-1-yl)but-2-en-1-ol 701-122-3 106185-75-5
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
26/10/2022
26/10/2022
12/12/2022
12/12/2022
Details
1,1'-(isopropylidene)bis[3,5-dibromo-4-(2,3-dibromo-2-methylpropoxy)benzene] 306-832-3 97416-84-7
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
01/07/2021
01/07/2021
16/08/2021
16/08/2021
Details
1,1'-[[3-(dimethylamino)propyl]imino]bispropan-2-ol 264-261-4 63469-23-8
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
22/09/2022
22/09/2022
07/11/2022
07/11/2022
Details
1,1,1,2,2,4,5,5,5-nonafluoro-4-(trifluoromethyl )-3-pentanone 436-710-6 756-13-8
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
22/04/2021
22/04/2021
07/06/2021
07/06/2021
Details
1,2,3,6-tetrahydromethyl-3,6-methanophthalic anhydride 246-644-8 25134-21-8
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
03/11/2023
03/11/2023
18/12/2023
18/12/2023
Details
1,2-dimethylimidazole 217-101-2 1739-84-0
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
10/05/2022
10/05/2022
27/06/2022
27/06/2022
Details
1,4-Benzenedicarboxylic acid, mixed Bu and 2-ethylhexyl diesters 946-149-3 1571954-81-8
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
21/05/2018
21/05/2018
05/07/2018
05/07/2018
Details
2,2-dimethyl-1,3-dioxolan-4-ylmethanol 202-888-7 100-79-8
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
25/05/2020
25/05/2020
09/07/2020
09/07/2020
Details
2,3-epoxypropyl neodecanoate 247-979-2 26761-45-5
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
25/05/2020
25/05/2020
09/07/2020
09/07/2020
Details
2-methylpentane-2,4-diol 203-489-0 107-41-5
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
26/03/2018
26/03/2018
11/05/2018
11/05/2018
Details
3-(trimethoxysilyl)propylamine 237-511-5 13822-56-5
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
26/04/2019
26/04/2019
10/06/2019
10/06/2019
Details
3-aminopropyltriethoxysilane 213-048-4 919-30-2
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
18/03/2021
18/03/2021
03/05/2021
03/05/2021
Details
3-chloropropyltrimethoxysilane 219-787-9 2530-87-2
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
26/08/2021
26/08/2021
11/10/2021
11/10/2021
Details
4,4,13,13-tetraethoxy-3,14-dioxa-8,9-dithia-4,13-disilahexadecane 260-350-7 56706-10-6
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
23/04/2018
23/04/2018
07/06/2018
07/06/2018
Details
4-hydroxy-4-methylpentan-2-one 204-626-7 123-42-2
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
01/09/2016
01/09/2016
17/10/2016
17/10/2016
Details
4-morpholinecarbaldehyde 224-518-3 4394-85-8
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
10/05/2022
10/05/2022
27/06/2022
27/06/2022
Details
8,9,10-trinorborn-2-ene 207-866-0 498-66-8
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
01/11/2015
01/11/2015
16/12/2015
16/12/2015
Details
Amides, C16-C18 (even) , N,N'-ethylenebis 931-299-4 68390-94-3
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
01/03/2023
01/03/2023
17/04/2023
17/04/2023
Details
Amines, polyethylenepoly-, triethylenetetramine fraction 292-588-2 90640-66-7
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
22/11/2017
22/11/2017
08/01/2018
08/01/2018


Details
Amines, polyethylenepoly-, triethylenetetramine fraction,Triethylenetetramine linear, cyclic and branched 292-588-2 90640-66-7
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
01/09/2017
01/09/2017
16/10/2017
16/10/2017
Details
Ashes (residues), plant 297-049-5 93333-79-0
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
31/01/2018
31/01/2018
19/03/2018
19/03/2018
Details
ASPHALT 232-490-9 8052-42-4
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
31/05/2016
31/05/2016
15/07/2016
15/07/2016
Details
barium titanium trioxide 234-975-0 12047-27-7
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
17/04/2015
17/04/2015
04/06/2015
04/06/2015
Details
Benzene, diethenyl- and Benzene, ethenylethyl- 910-757-7 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
16/08/2019
16/08/2019
30/09/2019
30/09/2019
Details
Biphenyl-4,4'-diol 202-200-5 92-88-6
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
26/04/2019
26/04/2019
10/06/2019
10/06/2019
Details
Chloroethane 200-830-5 75-00-3
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
10/03/2017
10/03/2017
25/04/2017
25/04/2017
Details
cobalt dichloride 231-589-4 7646-79-9
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
18/07/2016
18/07/2016
01/09/2016
01/09/2016


Details
Ditolyl ether 248-948-6 28299-41-4
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
21/10/2021
21/10/2021
07/12/2021
07/12/2021
Details
Docosan-1-ol 211-546-6 661-19-8
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
30/06/2023
30/06/2023
14/08/2023
14/08/2023
Details
dodecamethylpentasiloxane 205-492-2 141-63-9
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
17/06/2020
17/06/2020
03/08/2020
03/08/2020
Details
Ethylene 200-815-3 74-85-1
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
30/09/2021
30/09/2021
15/11/2021
15/11/2021
Details
Ethylenediamine, propoxylated 500-035-6 25214-63-5
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
26/04/2019
26/04/2019
10/06/2019
10/06/2019
Details
hexadecyltrimethoxysilane 240-464-3 16415-12-6
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
25/11/2021
25/11/2021
10/01/2022
10/01/2022
Details
Hexamethylcyclotrisiloxane 208-765-4 541-05-9
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
26/10/2022
26/10/2022
12/12/2022
12/12/2022
Details
Hexan-6-olide 207-938-1 502-44-3
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
16/12/2020
16/12/2020
01/02/2021
01/02/2021
Details
OO-tert-butyl O-(2-ethylhexyl) peroxycarbonate 252-029-5 34443-12-4
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
21/01/2021
21/01/2021
08/03/2021
08/03/2021
Details
pentaerythritol 204-104-9 115-77-5
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
20/12/2017
20/12/2017
05/02/2018
05/02/2018
Details
Peracetic acid 201-186-8 79-21-0
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
26/08/2021
26/08/2021
11/10/2021
11/10/2021
Details
Phthalic anhydride 201-607-5 85-44-9
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
18/03/2021
18/03/2021
03/05/2021
03/05/2021
Details
Polysulfides, bis[3-(triethoxysilyl)propyl] 915-673-4 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
28/02/2018
28/02/2018
16/04/2018
16/04/2018
Details
Reaction mass of 1,3-Propanediol, 2-(hydroxymethyl)-2-[(methoxymethoxy)methyl]- and 1,3-dioxane-5,5-dimethanol 911-819-6 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
16/08/2019
16/08/2019
30/09/2019
30/09/2019
Details
Reaction mass of 3-isopropyl-6-methylenecyclohexene and (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohexene and (4S)-1-methyl-4-(prop-1-en-2-yl)cyclohexene 939-009-8 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
22/09/2022
22/09/2022
07/11/2022
07/11/2022
Details
Reaction product of 2,4-Dinitrotoluene and 2,6-Dinitrotoluene and hydrogen 939-489-9 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
18/02/2021
18/02/2021
05/04/2021
05/04/2021
Details
Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid 931-291-0 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
23/03/2020
23/03/2020
07/05/2020
07/05/2020
Details
Sodium metavanadate 237-272-7 13718-26-8
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
25/01/2022
25/01/2022
11/03/2022
11/03/2022
Details
tert-dodecanethiol 246-619-1 25103-58-6
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
22/06/2017
22/06/2017
07/08/2017
07/08/2017
Details
tetrahydro-2-methylfuran 202-507-4 96-47-9
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
27/01/2020
27/01/2020
12/03/2020
12/03/2020
Details
Tris(2-butoxyethyl) phosphate 201-122-9 78-51-3
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
26/03/2018
26/03/2018
11/05/2018
11/05/2018
Details
tris[2-[2-(2-methoxyethoxy)ethoxy]ethyl] orthoborate 250-418-4 30989-05-0
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
29/04/2016
29/04/2016
13/06/2016
13/06/2016
Details
undec-10-enoic acid 203-965-8 112-38-9
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
20/05/2021
20/05/2021
05/07/2021
05/07/2021
Details
Bis[C5-(branched)-alkyl]l benzene-1,4-dicarboxylate   940-272-6 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity
Sub-chronic toxicity (90-day): oral
01/09/2017
01/09/2017
01/09/2017
16/10/2017
16/10/2017
16/10/2017
Details
Zinc, O,O-mixed (iso-Bu), (iso-Pr), (pentyl) phosphorodithioate 820-225-5 101747-77-7
Reproductive toxicity (extended one-generation reproductive toxicity study) “|| Note: testing proposed with [Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts] (EC 270-608-0)
Reproductive toxicity (pre-natal developmental toxicity) “|| Note: testing proposed with [Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts] (EC 270-608-0)
Sub-chronic toxicity (90-day): oral “|| Note: testing proposed with [Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts] (EC 270-608-0)
26/04/2019
26/04/2019
26/04/2019
10/06/2019
10/06/2019
10/06/2019
Details
Reaction mass of diisobutyl adipate and diisobutyl glutarate and diisobutyl succinate 907-870-9 -
Reproductive toxicity (extended one-generation reproductive toxicity study) ||Note: testing proposed with Reaction mass of dimethyl adipate and dimethyl glutarate and dimethyl succinate (EC 906-170-0 )
Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Reaction mass of dimethyl adipate and dimethyl glutarate and dimethyl succinate (EC 906-170-0 )
22/09/2022
22/09/2022
07/11/2022
07/11/2022
Details
2,2,4,4,6,8,8-heptamethylnonane 224-506-8 4390-04-9 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with two substances in a grouping approach: Icosane (EC 204-015-1) and Hydrocarbons, C14-C19, iso-alkanes, cyclics; aromatics <2% (920-114-2) 02/11/2018 17/12/2018 Details
Hydrocarbons, C14-C17, n-alkanes, <2% aromatics 917-828-1 - Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with two substances in a group: Icosane (EC 204-018-1) and Hydrocarbons, C14-C19, isoalkanes, cyclics, < 2% aromatics (920-114-2) 02/11/2018 17/12/2018 Details