Korábbi/eredmények
Korábbi/eredmények
Korábbi/eredmények
This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.
To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.
Butene | 246-689-3 | 25167-67-3 |
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with 2-methylpropene (EC no. 204-066-3) Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with 2-methylpropene (EC no. 204-066-3) Sub-chronic toxicity (90 day): inhalation||Note: testing proposed with 2-methylpropene (EC no. 204-066-3) |
06/06/2023 06/06/2023 06/06/2023 |
21/07/2023 21/07/2023 21/07/2023 |
Details | |
[1,3(or 1,4)-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide | 246-678-3 | 25155-25-3 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 27/05/2019 | 11/07/2019 | Details | |
[1,3(or 1,4)-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide | 246-678-3 | 25155-25-3 | Reproductive toxicity (pre-natal developmental toxicity) | 30/11/2015 | 14/01/2016 | Details | |
[1,3(or 1,4)-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide | 246-678-3 | 25155-25-3 |
Bioaccumulation aquatic / sediment Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
06/03/2012 06/03/2012 06/03/2012 |
20/04/2012 20/04/2012 20/04/2012 |
Details | |
Trixylyl phosphate | 246-677-8 | 25155-23-1 | Bioaccumulation aquatic / sediment | 02/09/2011 | 17/10/2011 | Details | |
1,2,3,6-tetrahydromethyl-3,6-methanophthalic anhydride | 246-644-8 | 25134-21-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
03/11/2023 03/11/2023 |
18/12/2023 18/12/2023 |
Details | |
tert-dodecanethiol | 246-619-1 | 25103-58-6 | Long-term toxicity to fish | 16/06/2022 | 01/08/2022 | Details | |
tert-dodecanethiol | 246-619-1 | 25103-58-6 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
22/06/2017 22/06/2017 |
07/08/2017 07/08/2017 |
Details | |
tert-dodecanethiol | 246-619-1 | 25103-58-6 | Sub-chronic toxicity (90 day): inhalation | 14/11/2013 | 30/12/2013 | Details | |
triethoxy(3-isocyanatopropyl)silane | 246-467-6 | 24801-88-5 | Genetic toxicity in vivo Note: testing proposed with 3-(Trimethoxysilyl)propyl isocyanate (EC 239-415-9) | 03/02/2016 | 21/03/2016 | Details | |
Triethoxy(3-isocyanatopropyl)silane | 246-467-6 | 24801-88-5 | Genetic toxicity in vivo | 18/03/2021 | 03/05/2021 | Details | |
Strontium bis(2-ethylhexanoate) | 219-536-3 | 2457-02-5 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with [strontium oxide] (EC 215-219-9) | 23/11/2020 | 07/01/2021 | Details | |
1,3,5-Tris(oxiran-2-ylmethyl)-1,3,5-triazinane-2,4,6-trione (TGIC) | 219-514-3 | 2451-62-9 | Reproductive toxicity (two-generation reproductive toxicity) | 19/11/2010 | 03/01/2011 | Details | |
2-(2H-benzotriazol-2-yl)-p-cresol | 219-470-5 | 2440-22-4 | Bioaccumulation aquatic / sediment | 18/06/2018 | 02/08/2018 | Details | |
Lithium phosphorodifluoridate | 643-080-8 | 24389-25-1 | Reproductive toxicity (pre-natal developmental toxicity) | 25/05/2020 | 09/07/2020 | Details | |
tetrasodium 2-(4-fluoro-6-(methyl-(2-(sulfatoethylsulfonyl)ethyl)amino)-1,3,5-triazin-2-ylamino)-5-hydroxy-6-(4-methyl-2-sulfonatophenylazo)naphthalene-1,7-disulfonate | 432-550-6 | 243858-01-7 | Genetic toxicity in vivo | 30/06/2023 | 14/08/2023 | Details | |
1,7-Naphthalenedisulfonic acid, 2-[[4-chloro-6-(cyanoamino)-1,3,5-triazin-2-yl]amino]-5-hydroxy-6-[2-[2-methoxy-5-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]diazenyl]-, lithium sodium salt (1:?:?) | 440-050-4 | 243857-97-8 | Genetic toxicity in vivo | 03/05/2023 | 19/06/2023 | Details | |
11-aminoundecanoic acid | 219-417-6 | 2432-99-7 | Reproductive toxicity (developmental toxicity) | 08/04/2010 | 24/05/2010 | Details | |
11-aminoundecanoic acid | 219-417-6 | 2432-99-7 | Long-term toxicity to fish | 03/10/2023 | 17/11/2023 | Details | |
Zinc bis(benzenesulphinate) | 246-148-1 | 24308-84-7 | Genetic toxicity in vivo | 25/05/2020 | 09/07/2020 | Details | |
1,4-bis(2,3-epoxypropoxy)butane | 219-371-7 | 2425-79-8 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): most appropriate route |
14/02/2011 14/02/2011 14/02/2011 |
31/03/2011 31/03/2011 31/03/2011 |
Details | |
1,4-bis(2,3-epoxypropoxy)butane | 219-371-7 | 2425-79-8 | Reproductive toxicity (extended one-generation reproductive toxicity study)|| Note: testing proposed with Reaction products of hexane-1,6-diol with 2-(chloromethyl)oxirane (1:2) (EC 618-939-5) | 23/03/2020 | 07/05/2020 | Details | |
2-Hexyldecan-1-ol | 219-370-1 | 2425-77-6 | Reproductive toxicity (two-generation reproductive toxicity) | 05/04/2011 | 20/05/2011 | Details | |
6-(isononanoylamino)hexanoic acid, compound with 2,2',2''-nitrilotriethanol (1:1) | 701-138-0 | 242482-67-3 | Reproductive toxicity (pre-natal developmental toxicity) | 01/09/2017 | 16/10/2017 | Details | |
Benzophenone-3,3':4,4'-tetracarboxylic dianhydride | 219-348-1 | 2421-28-5 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
14/08/2014 14/08/2014 |
28/09/2014 28/09/2014 |
Details | |
N-[2-[(2-cyano-4,6-dinitrophenyl)azo]-5-(diethylamino)phenyl]acetamide | 246-058-2 | 24170-60-3 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. | 23/11/2020 | 07/01/2021 | Details | |
1,1'-dithiobis[hexahydro-2H-azepin-2-one] | 245-910-0 | 23847-08-7 | Reproductive toxicity (pre-natal developmental toxicity) | 25/06/2015 | 10/08/2015 | Details | |
[3-(trimethoxysilyl)propyl]urea | 245-904-8 | 23843-64-3 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Urea, N-(3-silylpropyl)-, Si-(ethoxy and methoxy) derivs., (EC 601-461-6) || Note: Testing proposal is based on concern identified by the registrant | 07/07/2020 | 21/08/2020 | Details | |
3,6,9,12-tetraoxotridecanol | 245-883-5 | 23783-42-8 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 2-(2-(2-methoxyethoxy)ethoxy)ethanol (EC 203-962-1) | 21/10/2021 | 07/12/2021 | Details | |
[3-(triethoxysilyl)propyl]urea | 245-876-7 | 23779-32-0 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
17/04/2015 17/04/2015 |
04/06/2015 04/06/2015 |
Details | |
N1,N3‐bis(3‐methylphenyl)‐5‐[(3‐methylphenyl)sulfamoyl]benzene‐1,3‐dicarboxamide | 951-483-8 | 2375645-78-4 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/06/2022 16/06/2022 16/06/2022 |
01/08/2022 01/08/2022 01/08/2022 |
Details | |
2,4,6,8-tetramethylcyclotetrasiloxane | 219-137-4 | 2370-88-9 |
Sub-chronic toxicity (90-day): oral - |
22/11/2017 22/11/2017 |
08/01/2018 08/01/2017 |
Details | |
2,4,6,8-tetramethylcyclotetrasiloxane | 219-137-4 | 2370-88-9 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 25/05/2020 | 09/07/2020 | Details | |
2,4,6,8-tetramethylcyclotetrasiloxane | 219-137-4 | 2370-88-9 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90 day): inhalation |
15/09/2011 15/09/2011 15/09/2011 |
31/10/2011 31/10/2011 31/10/2011 |
Details | |
Methyl [3-(trimethoxysilyl)propyl]carbamate | 245-659-7 | 23432-62-4 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
10/03/2017 10/03/2017 10/03/2017 |
25/04/2017 25/04/2017 25/04/2017 |
Details | |
N-[3-(dimethoxymethylsilyl)-2-methylpropyl]ethylenediamine | 245-642-4 | 23410-40-4 |
Reproductive toxicity (pre-natal developmental toxicity) Note: Testing proposal is based on concern identified by the registrant. Testing proposed with N-(3-(trimethoxysilyl)propyl)ethylenediamine (EC 217-164-6) Sub-chronic toxicity (90-day): oral Note: Testing proposal is based on concern identified by the registrant. Testing proposed with N-(3-(trimethoxysilyl)propyl)ethylenediamine (EC 217-164-6) |
25/06/2015 25/06/2015 |
10/08/2015 10/08/2015 |
Details | |
2,2'-[oxybis(methylene)]-bis[2-ethylpropane-1,3-diol] | 245-509-0 | 23235-61-2 | Sub-chronic toxicity (90-day): oral | 30/09/2015 | 16/11/2015 | Details | |
2,2'-[oxybis(methylene)]-bis[2-ethylpropane-1,3-diol] | 245-509-0 | 23235-61-2 | Reproductive toxicity (developmental toxicity) | 26/01/2011 | 14/03/2011 | Details | |
2,2'-[oxybis(methylene)]-bis[2-ethylpropane-1,3-diol] | 245-509-0 | 23235-61-2 | Long-term toxicity to fish | 15/01/2024 | 29/02/2024 | Details | |
2,2'-[OXYBIS(METHYLENE)]BIS[2-ETHYLPROPANE-1,3-DIOL] | 245-509-0 | 23235-61-2 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
29/04/2016 29/04/2016 |
13/06/2016 13/06/2016 |
Details | |
2,2'-[oxybis(methylene)]bis[2-ethylpropane-1,3-diol] | 245-509-0 | 23235-61-2 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 26/03/2018 | 11/05/2018 | Details | |
Octyl octanoate | 218-980-5 | 2306-88-9 |
Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
03/04/2023 03/04/2023 03/04/2023 |
22/05/2023 22/05/2023 22/05/2023 |
Details | |
N,N’-di[3-(p-toluene sulfonyl)oxy]phenyl urea | 876-151-9 | 2292123-68-1 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) |
03/04/2023 03/04/2023 |
22/05/2023 22/05/2023 |
Details | |
N-phenyl-N-[(trichloromethyl)thio]benzenesulphonamide | 218-915-0 | 2280-49-1 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) |
18/02/2014 18/02/2014 |
04/04/2014 04/04/2014 |
Details | |
Tetraammonium ethylenediaminetetraacetate | 245-022-3 | 22473-78-5 | Sub-chronic toxicity (90 day): inhalation | 16/06/2011 | 01/08/2011 | Details | |
1,1,3,3-tetramethylbutyl 2-ethylperoxyhexanoate | 244-894-2 | 22288-43-3 | Genetic toxicity in vivo | 10/05/2022 | 27/06/2022 | Details | |
1,1,3,3-tetramethylbutyl 2-ethylperoxyhexanoate | 244-894-2 | 22288-43-3 | Reproductive toxicity (pre-natal developmental toxicity) | 03/03/2014 | 17/04/2014 | Details | |
4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl | 218-760-9 | 2226-96-2 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
14/08/2014 14/08/2014 |
28/09/2014 28/09/2014 |
Details | |
4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl | 218-760-9 | 2226-96-2 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/02/2015 16/02/2015 |
02/04/2015 02/04/2015 |
Details | |
butan-2-one O,O',O''-(vinylsilylidyne)trioxime | 218-747-8 | 2224-33-1 |
Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with Butan-2-one O,O',O''-(methylsilylidyne)trioxime (CAS 22984-54-9). |
25/06/2015 | 10/08/2015 | Details | |
Zinc O,O,O',O'-tetrakis(1,3-dimethylbutyl) bis(phosphorodithioate) | 218-679-9 | 2215-35-2 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) Testing proposed according to a plan for the ZDDP category Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) Testing proposed according to a plan for the ZDDP category. Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) Testing proposed according to a plan for the ZDDP category.“ |
04/10/2018 04/10/2018 04/10/2018 |
19/11/2018 19/11/2018 19/11/2018 |
Details | |
Zinc O,O,O',O'-tetrakis(1,3-dimethylbutyl) bis(phosphorodithioate) | 218-679-9 | 2215-35-2 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with, zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), and Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1) Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), and zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5) |
21/12/2021 21/12/2021 21/12/2021 |
04/02/2022 04/02/2022 04/02/2022 |
Details | |
[1,3-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide | 218-664-7 | 2212-81-9 |
Bioaccumulation aquatic / sediment Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/05/2012 16/05/2012 16/05/2012 |
02/07/2012 02/07/2012 02/07/2012 |
Details | |
[1,3-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide | 218-664-7 | 2212-81-9 | Reproductive toxicity (extended one-generation reproductive toxicity study) “|| Note: testing proposed with [1,3(or 1,4)-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide CAS: 25155-25-3)” | 25/05/2020 | 09/07/2020 | Details | |
[1,3-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide | 218-664-7 | 2212-81-9 |
Bioaccumulation aquatic / sediment Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant |
20/10/2016 20/10/2016 |
05/12/2016 05/12/2016 |
Details | |
2,3-epoxypropyl o-tolyl ether | 218-645-3 | 2210-79-9 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
16/05/2014 16/05/2014 16/05/2014 |
30/06/2014 30/06/2014 30/06/2014 |
Details | |
12-hydroxyoctadecanoic acid, reaction products with 1,3-benzenedimethanamine and hexamethylenediamine | 432-840-2 | 220926-97-6 | Repeated dose toxicity: Inhalation | 04/05/2010 | 18/06/2010 | Details | |
S-(3-(triethoxysilyl)propyl)octanethioate | 436-690-9 | 220727-26-4 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
25/09/2012 25/09/2012 25/09/2012 |
12/11/2012 12/11/2012 12/11/2012 |
Details | |
S-(3-(triethoxysilyl)propyl)octanethioate | 436-690-9 | 220727-26-4 |
Reproductive toxicity (extended one-generation reproductive toxicity study Reproductive toxicity (pre-natal developmental toxicity) |
18/03/2021 18/03/2021 |
03/05/2021 03/05/2021 |
Details | |
1,1'-(isopropylidene)bis[3,5-dibromo-4-(2,3-dibromopropoxy)benzene] | 244-617-5 | 21850-44-2 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
18/09/2014 18/09/2014 |
03/11/2014 03/11/2014 |
Details | |
4-((Triethoxysilyl)methyl) morpholine | 480-370-1 | 21743-27-1 |
Reproductive toxicity (developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day) |
27/11/2009 27/11/2009 27/11/2009 |
11/01/2010 11/01/2010 11/01/2010 |
Details | |
tin monoxide | 244-499-5 | 21651-19-4 | Sub-chronic toxicity (90 day): inhalation | 23/01/2015 | 09/03/2015 | Details | |
2-methyl-1,3-propanediol | 412-350-5 | 2163-42-0 | Long-term toxicity to fish | 15/01/2024 | 29/02/2024 | Details | |
Bis(2,6-diisopropylphenyl)carbodiimide | 218-487-5 | 2162-74-5 | Reproductive toxicity (pre-natal developmental toxicity) | 22/09/2022 | 07/11/2022 | Details | |
N-{2-[(phenylcarbamoyl)amino]phenyl}benzenesulfonamide | 806-543-7 | 215917-77-4 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant | 30/11/2015 | 14/01/2016 | Details | |
N-{2-[(phenylcarbamoyl)amino]phenyl}benzenesulfonamide | 806-543-7 | 215917-77-4 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
24/02/2020 24/02/2020 |
09/04/2020 09/04/2020 |
Details | |
Dibutyl itaconate | 218-451-9 | 2155-60-4 |
Genetic toxicity in vivo Sub-chronic toxicity (90-day): oral |
24/02/2020 24/02/2020 |
09/04/2020 09/04/2020 |
Details | |
Vinyl laurate | 218-414-7 | 2146-71-6 | Sub-chronic toxicity (90-day): oral | 16/05/2011 | 30/06/2011 | Details | |
N'-(1,3-dimethylbutylidene)-3-hydroxy-2-naphthohydrazide | 435-860-1 | 214417-91-1 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
17/04/2012 17/04/2012 |
01/06/2012 01/06/2012 |
Details | |
N'-(1,3-dimethylbutylidene)-3-hydroxy-2-naphthohydrazide | 435-860-1 | 214417-91-1 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
25/05/2020 25/05/2020 |
09/07/2020 09/07/2020 |
Details | |
6-(cyclohexylamino)-3-methyl-3H-dibenz[f,ij]isoquinoline-2,7-dione | 244-320-0 | 21295-57-8 | Genetic toxicity in vivo | 26/08/2021 | 11/10/2021 | Details | |
2-[(2-methyl-1-oxoallyl)oxy]ethyl acetoacetate | 244-311-1 | 21282-97-3 | Genetic toxicity in vivo | 29/04/2014 | 13/06/2014 | Details | |
Fatty acids, C16-C18 and C18-unsatd., ME esters, epoxidized, reaction products with ethylen glycol | 606-712-3 | 211450-54-3 | Reproductive toxicity (pre-natal developmental toxicity) | 04/04/2014 | 19/05/2014 | Details | |
2-tert-butyl-1,4-dimethoxybenzene | 244-216-5 | 21112-37-8 | Genetic toxicity in vivo | 18/03/2021 | 03/05/2021 | Details | |
Cobalt dihydroxide | 244-166-4 | 21041-93-0 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
02/09/2011 02/09/2011 02/09/2011 |
17/10/2011 17/10/2011 17/10/2011 |
Details | |
Cobalt dihydroxide | 244-166-4 | 21041-93-0 |
Carcinogenicity
|| Note: testing proposed with Cobalt dichloride (EC 231-589-4) Genetic toxicity in vivo
|| Note: testing proposed with Cobalt sulphate (EC 233-334-2) |
21/01/2021 21/01/2021 |
08/03/2021 08/03/2021 |
Details | |
Diammonium dihydrogen ethylenediaminetetraacetate | 244-063-4 | 20824-56-0 | Sub-chronic toxicity (90 day): inhalation | 29/07/2011 | 12/09/2011 | Details | |
8,9,10,11-tetrachloro-12H-phthaloperin-12-one | 244-007-9 | 20749-68-2 | Reproductive toxicity (pre-natal developmental toxicity) | 14/08/2014 | 28/09/2014 | Details | |
Disilver oxide | 243-957-1 | 20667-12-3 | Sub-chronic toxicity (90-day): oral | 15/04/2011 | 30/05/2011 | Details | |
Tetraammineplatinum dinitrate | 243-929-9 | 20634-12-2 | Genetic toxicity in vivo || Note: testing proposed with tetraammineplatinum(II) dichloride. Testing proposal is based on concern identified by the registrant. | 28/02/2018 | 16/04/2018 | Details | |
N-butyl 4-oxopentanoate | 218-143-4 | 2052-15-5 |
Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Levulinic acid (EC 204-649-2) Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with Levulinic acid (EC 204-649-2) |
23/11/2020 23/11/2020 |
07/01/2021 07/01/2021 |
Details | |
triethoxy(methyl)silane | 217-983-9 | 2031-67-6 | Sub-chronic toxicity (90-day): oral | 25/05/2020 | 09/07/2020 | Details | |
triethoxy(methyl)silane | 217-983-9 | 2031-67-6 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with trimethoxy(methyl)silane. | 16/10/2014 | 01/12/2014 | Details | |
Sodium 4-oxovalerate | 243-378-4 | 19856-23-6 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/06/2018 18/06/2018 |
02/08/2018 02/08/2018 |
Details | |
Methanal, reaction products with 1,3-bis(aminomethyl)benzene and hydroxybenzen | 701-207-5 | 1950616-36-0 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
21/05/2018 21/05/2018 21/05/2018 |
05/07/2018 05/07/2018 05/07/2018 |
Details | |
Hexahydro-4-methylphthalic anhydride | 243-072-0 | 19438-60-9 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 28/02/2018 | 16/04/2018 | Details | |
3,3,4,4,5,5,6,6,6-nonafluorohexene | 243-053-7 | 19430-93-4 | Sub-chronic toxicity (90 day): inhalation | 14/08/2014 | 28/09/2014 | Details | |
benzyl butyl cis-cyclohexane-1,2-dicarboxylate | 701-279-8 | 1931129-39-3 |
Long-term toxicity to fish || Note: Link to the registration dossier not given as the dossier not yet disseminated. || Note: this substance was previously registered, identified and disseminated with EC No. 810-685-5 Reproductive toxicity (pre-natal developmental toxicity) || Note: Link to registration dossier not given as the dossier not yet disseminated. || Note: this substance was previously registered, identified and disseminated with EC No. 810-685-5 Sub-chronic toxicity (90-day): oral || Note: Link to registration dossier not given as the dossier not yet disseminated. || Note: this substance was previously registered, identified and disseminated with EC No. 810-685-5 |
10/12/2018 10/12/2018 10/12/2018 |
24/01/2019 24/01/2019 24/01/2019 |
Details | |
OO-tert-butyl monoperoxymaleate | 217-691-1 | 1931-62-0 | Genetic toxicity in vivo | 23/11/2020 | 07/01/2021 | Details | |
A mixture of: triphenylthiophosphate and tertiary butylated phenyl derivatives | 421-820-9 | 192268-65-8 | Long-term toxicity to fish||Note: testing proposed with O,O,O-triphenyl phosphorothioate (EC no. 209-909-9) | 04/12/2023 | 18/01/2024 | Details | |
reaction mass of: triphenylthiophosphate and tertiary butylated phenyl derivatives | 421-820-9 | 192268-65-8 | Reproductive toxicity (pre-natal developmental toxicity) | 16/10/2014 | 01/12/2014 | Details | |
Di(tetraethylammonium)hexahydroxoplatinate(IV) | 848-537-7 | 1912392-88-1 | Genetic toxicity in vivo | 21/09/2020 | 05/11/2020 | Details | |
Potassium hexadecyl hydrogen phosphate | 242-768-1 | 19035-79-1 | Reproductive toxicity (pre-natal developmental toxicity) | 20/05/2021 | 05/07/2021 | Details | |
Peroxyacetic acid, reaction products with N2,N2’-1,6-hexanediylbis[N4,N6-dibutyl-N2,N4,N6-tris(2,2,6,6,tetramethyl-4-piperidinyl)-1,3,5-triazine-2,4,6-triamine, hydrogenated | 812-927-5 | 1902936-62-2 | Reproductive toxicity (pre-natal developmental toxicity) | 10/08/2018 | 24/09/2018 | Details | |
1,1'-(1,1,2,2-tetramethylethylene)dibenzene | 217-568-2 | 1889-67-4 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/02/2014 18/02/2014 |
04/04/2014 04/04/2014 |
Details | |
N-acetylhexanelactam | 217-565-6 | 1888-91-1 | Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant | 17/06/2020 | 03/08/2020 | Details | |
Octacos-1-ene | 242-616-4 | 18835-34-2 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
31/05/2011 31/05/2011 |
15/07/2011 15/07/2011 |
Details | |
Hexacos-1-ene | 242-615-9 | 18835-33-1 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
31/05/2011 31/05/2011 |
15/07/2011 15/07/2011 |
Details | |
(E)-7,11-dimethyl-3-methylenedodeca-1,6,10-triene | 242-582-0 | 18794-84-8 | Sub-chronic toxicity (90-day): oral | 23/04/2018 | 07/06/2018 | Details | |
6-tert-butyl-2,4-xylenol | 217-533-1 | 1879-09-0 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) |
18/02/2021 18/02/2021 |
05/04/2021 05/04/2021 |
Details | |
6-tert-butyl-2,4-xylenol | 217-533-1 | 1879-09-0 | Long-term toxicity to fish | 15/07/2014 | 29/08/2014 | Details | |
1,1,1,3,5,5,5-heptamethyltrisiloxane | 217-496-1 | 1873-88-7 |
Reproductive toxicity (pre-natal developmental toxicity)
Note: testing proposed with Octamethyltrisiloxane, CAS 107-51-7 and 1,1,3,3-tetramethyldisiloxane, CAS 3277-26-7 Sub-chronic toxicity (90 day): inhalation
Note: testing proposed with 1,1,3,3-tetramethyldisiloxane, CAS 3277-26-7. |
25/06/2015 25/06/2015 |
10/08/2015 10/08/2015 |
Details | |
Fatty acids, tall-oil, reaction products with bisphenol A, epichlorohydrin, glycidyl tolyl ether and triethylenetetramine | 606-078-8 | 186321-96-0 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
04/04/2014 04/04/2014 |
19/05/2014 19/05/2014 |
Details | |
3-hydroxy-2-(hydroxymethyl)-2-methylpropanal | 242-393-3 | 18516-18-2 |
Genetic toxicity in vivo Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/06/2011 16/06/2011 16/06/2011 16/06/2011 |
01/08/2011 01/08/2011 01/08/2011 01/08/2011 |
Details | |
[No public or meaningful name is available] | 944-258-0 | 1850357-57-1 | Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Wax, rice bran, oxidized (Polar modified Rice Bran Wax) | 03/05/2023 | 19/06/2023 | Details | |
Strontium hydroxide | 242-367-1 | 18480-07-4 |
Long-term toxicity to fish
Note: testing proposed with strontium dinitrate (EC: 233-131-9, CAS: 10042-76-9) Reproductive toxicity (pre-natal developmental toxicity)
Note: testing proposed with strontium dinitrate (EC: 233-131-9, CAS: 10042-76-9) Reproductive toxicity (two-generation reproductive toxicity)
Note: testing proposed with strontium dinitrate (EC: 233-131-9, CAS: 10042-76-9) |
15/04/2014 15/04/2014 15/04/2014 |
30/05/2014 30/05/2014 30/05/2014 |
Details | |
2,6-dimethyloct-7-en-2-ol | 242-362-4 | 18479-58-8 | Reproductive toxicity (pre-natal developmental toxicity) | 26/08/2021 | 11/10/2021 | Details | |
2,6-dimethyloct-7-en-2-ol | 242-362-4 | 18479-58-8 | Reproductive toxicity (two-generation reproductive toxicity) | 14/02/2011 | 31/03/2011 | Details | |
2,6-dimethyloct-7-en-2-ol | 242-362-4 | 18479-58-8 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 01/09/2017 | 16/10/2017 | Details | |
2,6-dimethyloct-7-en-2-ol | 242-362-4 | 18479-58-8 | Long-term toxicity to fish | 03/10/2023 | 17/11/2023 | Details | |
Octabenzone | 217-421-2 | 1843-05-6 | Reproductive toxicity (pre-natal developmental toxicity) | 18/02/2013 | 04/04/2013 | Details | |
(3-chloropropyl)dimethoxymethylsilane | 242-056-0 | 18171-19-2 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with (3-chloropropyl)triethoxysilane (EC 225-805-6)” | 17/04/2015 | 04/06/2015 | Details | |
(3-chloropropyl)dimethoxymethylsilane | 242-056-0 | 18171-19-2 | Sub-chronic toxicity (90-day): oral | 25/05/2020 | 09/07/2020 | Details | |
1,2-diacetoxybut-3-ene | 421-720-5 | 18085-02-4 | Sub-chronic toxicity (90-day): oral | 25/11/2021 | 10/01/2022 | Details | |
1,1,1,3,5,5,5-heptamethyl-3-octyltrisiloxane | 241-881-3 | 17955-88-3 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
17/06/2020 17/06/2020 |
03/08/2020 03/08/2020 |
Details | |
1,1,1,3,5,5,5-heptamethyl-3-[(trimethylsilyl)oxy]trisiloxane | 241-867-7 | 17928-28-8 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with decamethyltetrasiloxane (EC no. 205-491-7, CAS no. 141-62-8) | 12/12/2014 | 26/01/2015 | Details | |
2,4,7,9-tetramethyl-4,7-decanediol | 451-160-7 | 17913-76-7 |
Long-term toxicity to fish "|| Note: testing proposed with 2,4,7,9-tetramethyldec-5-yne-4,7-diol (EC 204-809-1, CAS 126-86-3) Reproductive toxicity (pre-natal developmental toxicity) |
17/09/2019 17/09/2019 |
01/11/2019 01/11/2019 |
Details | |
N-(cyclohexylthio)phthalimide | 241-774-1 | 17796-82-6 |
Bioaccumulation: aquatic / sediment Long-term or reproductive toxicity to birds Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
01/07/2011 01/07/2011 01/07/2011 01/07/2011 17/12/2012 |
15/08/2011 15/08/2011 15/08/2011 15/08/2011 31/01/2013 |
Details | |
3-hydroxy-2-(3-hydroxy-2-quinolyl)-1H-inden-1-one | 241-753-7 | 17772-51-9 | Reproductive toxicity (pre-natal developmental toxicity) | 31/08/2015 | 15/10/2015 | Details | |
1,3,5-triazine-2,4,6(1H,3H,5H)-trithione, trisodium salt | 241-749-5 | 17766-26-6 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
14/08/2014 14/08/2014 |
28/09/2014 28/09/2014 |
Details | |
Sodium hydrogen m-sulphonatobenzoate | 241-602-5 | 17625-03-5 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
03/04/2023 03/04/2023 |
22/05/2023 22/05/2023 |
Details | |
N-(3-(trimethoxysilyl)propyl)ethylenediamine | 217-164-6 | 1760-24-3 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
03/03/2014 03/03/2014 |
17/04/2014 17/04/2014 |
Details | |
Aminoiminomethanesulphinic acid | 217-157-8 | 1758-73-2 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
16/05/2014 16/05/2014 |
30/06/2014 30/06/2014 |
Details | |
N,N''-(4-methyl-m-phenylene)bis[N',N'-dimethylurea] | 241-523-6 | 17526-94-2 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
23/03/2020 23/03/2020 |
07/05/2020 07/05/2020 |
Details | |
p-tert-butylstyrene | 217-126-9 | 1746-23-2 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant. | 25/05/2020 | 09/07/2020 | Details | |
2-Hydroxy-5-nonyl(branched)-benzaldehyde oxime | 605-717-8 | 174333-80-3 | Long-term toxicity to fish | 22/06/2017 | 07/08/2017 | Details | |
1,2-dimethylimidazole | 217-101-2 | 1739-84-0 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
19/10/2020 19/10/2020 |
03/12/2020 03/12/2020 |
Details | |
1,2-dimethylimidazole | 217-101-2 | 1739-84-0 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
10/05/2022 10/05/2022 |
27/06/2022 27/06/2022 |
Details | |
3,4-dihydroxybenzonitrile | 241-367-9 | 17345-61-8 | Genetic toxicity in vivo | 17/06/2020 | 03/08/2020 | Details | |
Barium hydroxide | 241-234-5 | 17194-00-2 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
16/12/2011 16/12/2011 |
30/01/2012 30/01/2012 |
Details | |
Barium hydroxide | 241-234-5 | 17194-00-2 | Long-term toxicity to fish | 29/04/2011 | 14/06/2011 | Details | |
Barium hydroxide | 241-234-5 | 17194-00-2 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Barium chloride dihydrate (EC 600-412-6) | 16/12/2020 | 01/02/2021 | Details | |
chlorodimethylvinylsilane | 217-007-1 | 1719-58-0 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Trimethylsilanol (CAS 1066-40-6) | 12/12/2014 | 26/01/2015 | Details | |
Lithium bis(fluorosulfonyl)imide | 686-526-7 | 171611-11-3 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
21/10/2021 21/10/2021 21/10/2021 |
07/12/2021 07/12/2021 07/12/2021 |
Details | |
N-(2-ethylhexyl)isononan-1-amide | 810-288-7 | 1700656-13-8 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
26/08/2021 26/08/2021 |
11/10/2021 11/10/2021 |
Details | |
Hexachloroplatinic acid | 241-010-7 | 16941-12-1 | Genetic toxicity in vivo || Note: testing proposed with Diammonium hexachloroplatinate (EC 241-010-7). Testing proposal is based on concern identified by the registrant. | 26/03/2018 | 11/05/2018 | Details | |
dipotassium heptafluorotantalate | 240-986-1 | 16924-00-8 | Genetic toxicity in vivo | 16/03/2015 | 30/04/2015 | Details | |
Dipotassium hexachloroplatinate | 240-979-3 | 16921-30-5 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. | 26/03/2018 | 11/05/2018 | Details | |
Diammonium hexachloroplatinate | 240-973-0 | 16919-58-7 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. | 23/04/2018 | 07/06/2018 | Details | |
1,3-Butanediol, reaction products with 1,1'-methylenebis[4-isocyanatobenzene], propylene glycol and tripropylene glycol | 941-496-7 | 1689576-89-3 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC 202-966-0) | 01/04/2022 | 16/05/2022 | Details | |
benzyl 3-isobutyryloxy-1-isopropyl-2,2-dimethylpropyl phthalate | 240-920-1 | 16883-83-3 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
16/06/2011 16/06/2011 |
01/08/2011 01/08/2011 |
Details | |
Dimethoxymethylsilane | 240-914-9 | 16881-77-9 | Sub-chronic toxicity (90-day): oral | 25/05/2020 | 09/07/2020 | Details | |
dimethoxymethylsilane | 240-914-9 | 16881-77-9 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with trimethoxy(methyl)silane. | 16/10/2014 | 01/12/2014 | Details | |
1,5-bis[1,2-bis(ethoxycarbonyl)ethylamino]-2-methylpentane | 433-260-2 | 168253-59-6 |
Reproductive toxicity (developmental toxicity) Sub-chronic toxicity (90-day): oral |
06/09/2010 06/09/2010 |
20/10/2010 20/10/2010 |
Details | |
diammonium hexanitratocerate | 240-827-6 | 16774-21-3 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Cerium (III) nitrate (CAS 10294-41-4) | 20/05/2015 | 06/07/2015 | Details | |
1-methyl-4-(methylsulfonyl)-2-nitrobenzene | 430-550-0 | 1671-49-4 | Genetic toxicity in vivo | 16/05/2011 | 30/06/2011 | Details | |
potassium 4-cumenesulfonate | 629-764-9 | 164524-02-1 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Sodium xylene sulphonate (EC 215-090-9) | 16/12/2016 | 30/01/2017 | Details | |
potassium 4-cumenesulfonate | 629-764-9 | 164524-02-1 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with sodium (xylenes and 4-ethylbenzene) sulphonate Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with sodium cumene sulphonate |
22/06/2017 22/06/2017 |
07/08/2017 07/08/2017 |
Details | |
potassium 4-isopropylbenzenesulphonate | 629-764-9 | 164524-02-1 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 25/06/2015 | 10/08/2015 | Details | |
3-((C12-18)-acylamino)-N-(2-((2-hydroxyethyl)amino)-2-oxoethyl)-N,N-dimethyl-1-propanaminium chloride | 427-370-1 | 164288-56-6 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 03/04/2023 | 22/05/2023 | Details | |
Triethoxyhexadecylsilane | 240-465-9 | 16415-13-7 |
Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Hexadecyltrimethoxysilane (EC 240-464-3) || Note: Testing proposal is based on concern identified by the registrant Sub-chronic toxicity (90-day): oral |
07/07/2020 07/07/2020 |
21/08/2020 21/08/2020 |
Details | |
hexadecyltrimethoxysilane | 240-464-3 | 16415-12-6 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 25/05/2020 | 09/07/2020 | Details | |
hexadecyltrimethoxysilane | 240-464-3 | 16415-12-6 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/10/2014 16/10/2014 |
01/12/2014 01/12/2014 |
Details | |
hexadecyltrimethoxysilane | 240-464-3 | 16415-12-6 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
25/11/2021 25/11/2021 |
10/01/2022 10/01/2022 |
Details | |
Reaction mass of (2S-cis)-tetrahydro-4-methyl-2-(2-methyl-1-propenyl)-2H-pyran and Tetrahydro-4-methyl-2-(2-methylpropen-1-yl)pyran (2R,4R) and Tetrahydro-4-methyl-2-(2-methylpropen-1-yl)pyran (2S,4S) and (2R-cis)-tetrahydro-4-methyl-2-(2-methyl-1-propenyl)-2H-pyran | 939-429-1 | 16409-43-1 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
30/11/2015 30/11/2015 |
14/01/2016 14/01/2016 |
Details | |
3-(Trimethoxysilyl)propyl (2E,4E)-hexa-2,4-dienoate | 642-902-2 | 163802-53-7 | Genetic toxicity in vivo | 10/03/2017 | 25/04/2017 | Details | |
Strontium carbonate | 216-643-7 | 1633-05-2 | Long-term toxicity to fish | 31/05/2011 | 15/07/2011 | Details | |
Hexamethylene diisocyanate, oligomerisation product, blocked with 3,5-dimethyl-1H-pyrazole | 605-318-9 | 163206-31-3 | Sub-chronic toxicity (90 day): inhalation | 12/12/2014 | 26/01/2015 | Details | |
Phenyl bis(2,4,6-trimethylbenzoyl)-phosphine oxide | 423-340-5 | 162881-26-7 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
22/12/2010 22/12/2010 22/12/2010 |
07/02/2011 07/02/2011 07/02/2011 |
Details | |
Condensation products of dimerised fatty acids, C18-unsaturated, with N,N-dimethyl-1,3-propanediamine and 1,3-propanediamine | 605-296-0 | 162627-17-0 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90 day): oral |
14/08/2014 14/08/2014 14/08/2014 |
28/09/2014 28/09/2014 28/09/2014 |
Details | |
(Z)-N-octadec-9-enylhexadecan-1-amide | 240-367-6 | 16260-09-6 | Reproductive toxicity (pre-natal developmental toxicity) | 14/08/2014 | 28/09/2014 | Details | |
Tris(2,5,8,11-tetraoxatridecyl) orthoborate | 310-290-3 | 161907-80-8 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
15/09/2011 15/09/2011 15/09/2011 |
31/10/2011 31/10/2011 31/10/2011 |
Details | |
2,2-dimethyl-3-oxopropyl acetate | 811-188-6 | 16184-79-5 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. | 01/09/2017 | 16/10/2017 | Details | |
Bis(2-ethylhexyl) peroxydicarbonate | 240-282-4 | 16111-62-9 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/04/2014 15/04/2014 |
30/05/2014 30/05/2014 |
Details | |
Hexafluoropropene, oxidized, oligomers, reduced, fluorinated | 500-537-5 | 161075-00-9 | Bioaccumulation aquatic / sediment | 16/10/2014 | 01/12/2014 | Details | |
1,6-bis(2,3-epoxypropoxy)hexane | 240-260-4 | 16096-31-4 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): dermal |
15/03/2011 15/03/2011 15/03/2011 |
29/04/2011 29/04/2011 29/04/2011 |
Details | |
1,6-bis(2,3-epoxypropoxy)hexane | 240-260-4 | 16096-31-4 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): dermal |
15/09/2011 15/09/2011 15/09/2011 |
31/10/2011 31/10/2011 31/10/2011 |
Details | |
Fatty acids, tall oil, oligomeric reaction products with maleic anhydride and rosin, calcium magnesium zinc salts, consisting of mainly calcium, magnesium, zinc salts of maleated rosin, fatty acids and rosin | 500-451-8 | 160901-14-4 |
Reproductive toxicity (pre-natal developmental toxicity) //Note: to be tested with Rosin, maleated (CAS RN 8050-28-0) Reproductive toxicity (two-generation reproductive toxicity) //Note: Testing proposed with Rosin, Fumarated (CAS RN 65997-04-7) Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin, fumarated (CAS RN 65997-04-7) and Rosin, maleated (CAS RN 8050-28-0) |
02/07/2013 02/07/2013 02/07/2013 |
16/08/2013 16/08/2013 16/08/2013 |
Details | |
Fatty acids, tall-oil, oligomeric reaction products with maleic anhydride and rosin, calcium magnesium zinc salts | 500-451-8 | 160901-14-4 | Reproductive toxicity (pre-natal developmental toxicity) | 06/03/2012 | 20/04/2012 | Details | |
4,4,7,7-tetraethoxy-3,8-dioxa-4,7-disiladecane | 240-212-2 | 16068-37-4 |
Genetic toxicity in vivo
|| Note: Testing proposal is based on concern identified by the registrant Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
17/06/2020 17/06/2020 17/06/2020 17/06/2020 |
03/08/2020 03/08/2020 03/08/2020 03/08/2020 |
Details | |
1-hydroxy-4-[[4-[(methylsulphonyl)oxy]phenyl]amino]anthraquinone | 216-475-4 | 1594-08-7 | Genetic toxicity in vivo | 01/07/2021 | 16/08/2021 | Details | |
Triammonium hydrogen ethylenediaminetetraacetate | 240-073-8 | 15934-01-7 | Sub-chronic toxicity (90 day): inhalation | 16/06/2011 | 01/08/2011 | Details | |
A mixture of: bis[4-diphenylsulfoniumphenyl]sulfide-bishexafluoroantimonate; thiophenoxyphenylsulfonium hexafluoroantimonate | 403-500-0 | 159120-95-3 | Genetic toxicity in vivo | 03/10/2023 | 17/11/2023 | Details | |
Propylidynetrimethanol, ethoxylated, esters with acrylic acid, reaction products with diethylamine | 500-425-6 | 159034-91-0 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
26/08/2021 26/08/2021 |
11/10/2021 11/10/2021 |
Details | |
Propylidynetrimethanol, ethoxylated, esters with acrylic acid, reaction products with diethylamine | 500-425-6 | 159034-91-0 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant | 16/12/2020 | 01/02/2021 | Details | |
2,2-bis[[(1-oxopentyl)oxy]methyl]propane-1,3-diyl divalerate | 239-937-7 | 15834-04-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 21/10/2019 | 05/12/2019 | Details | |
Fatty acids, C16-C18 and C18-unsatd., ME esters, epoxidized | 605-143-8 | 158318-67-3 | Reproductive toxicity (pre-natal developmental toxicity) | 16/05/2014 | 30/06/2014 | Details | |
Tri(isopropyl)silyl acrylate | 457-670-6 | 157859-20-6 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
31/08/2015 31/08/2015 |
15/10/2015 15/10/2015 |
Details | |
Tri(isopropyl)silyl acrylate | 457-670-6 | 157859-20-6 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
31/08/2015 31/08/2015 |
15/10/2015 15/10/2015 |
Details | |
sodium cumenesulphonate | 239-854-6 | 15763-76-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 16/12/2016 | 30/01/2017 | Details | |
Sodium p-cumenesulphonate | 239-854-6 | 15763-76-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Sodium (xylenes and 4-ethylbenzene) sulphonate Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with sodium cumene sulphonate |
22/06/2017 22/06/2017 |
07/08/2017 07/08/2017 |
Details | |
sodium p-cumenesulphonate | 239-854-6 | 15763-76-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Sodium xylene sulphonate | 24/04/2015 | 12/06/2015 | Details | |
Alcohols, C16-18 and C18-unsatd., ethoxylated, sulfates, sodium salts | 500-345-1 | 157627-95-7 | Reproductive toxicity (pre-natal developmental toxicity) | 30/06/2023 | 14/08/2023 | Details | |
Disodium; 4-Amino-3-{4-[4-(2,4-diamino-phenylazo)-benzenesulfonylamino]-phenylazo}-5-hydroxy-6-phenylazo-naphthalene-2,7-disulfonate | 605-104-5 | 157577-99-6 | Genetic toxicity in vivo | 26/08/2021 | 11/10/2021 | Details | |
bis(4-(1,1,3,3-tetramethylbutyl)phenyl)amine | 239-816-9 | 15721-78-5 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
18/02/2014 18/02/2014 18/02/2014 |
04/04/2014 04/04/2014 04/04/2014 |
Details | |
1,4-Benzenedicarboxylic acid, mixed Bu and 2-ethylhexyl diesters | 946-149-3 | 1571954-81-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
21/05/2018 21/05/2018 |
05/07/2018 05/07/2018 |
Details | |
[1R-(1α,2β,5α)]-1-(isopropyl)-2-methoxy-4-methylcyclohexane | 216-365-6 | 1565-76-0 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant | 19/10/2020 | 03/12/2020 | Details | |
2-ethyl-2-[[(1-oxoallyl)oxy]methyl]-1,3-propanediyl diacrylate; 2,2-bis(acryloyloxymethyl)butyl acrylate; trimethylolpropane triacrylate | 239-701-3 | 15625-89-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Sub-chronic toxicity (90-day): oral |
25/05/2020 25/05/2020 |
09/07/2020 09/07/2020 |
Details | |
2-ethyl-2-[[(1-oxoallyl)oxy]methyl]-1,3-propanediyl diacrylate; 2,2-bis(acryloyloxymethyl)butyl acrylate; trimethylolpropane triacrylate | 239-701-3 | 15625-89-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 26/10/2022 | 12/12/2022 | Details | |
Cobalt(2+) propionate | 216-333-1 | 1560-69-6 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
02/09/2011 02/09/2011 02/09/2011 |
17/10/2011 17/10/2011 17/10/2011 |
Details | |
Calcium cyanamide | 205-861-8 | 156-62-7 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 28/02/2018 | 16/04/2018 | Details | |
calcium cyanamide | 205-861-8 | 156-62-7 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
15/04/2011 15/04/2011 |
30/05/2011 30/05/2011 |
Details | |
2,2'-azobis[4-methoxy-2,4-dimethylvaleronitrile] | 239-593-8 | 15545-97-8 | Genetic toxicity in vivo | 17/06/2020 | 03/08/2020 | Details | |
Diphosphoric acid, compound with 1,3,5-triazine-2,4,6-triamine | 239-590-1 | 15541-60-3 | Reproductive toxicity (pre-natal developmental toxicity) | 26/08/2021 | 11/10/2021 | Details | |
bis(4-tert-butylcyclohexyl) peroxydicarbonate | 239-557-1 | 15520-11-3 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/07/2014 15/07/2014 |
29/08/2014 29/08/2014 |
Details | |
2,2'-(octylimino)bisethanol | 239-555-0 | 15520-05-5 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
25/11/2019 25/11/2019 |
09/01/2020 09/01/2020 |
Details | |
3-(trimethoxysilyl)propyl isocyanate | 239-415-9 | 15396-00-6 |
Genetic toxicity in vivo Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: it is proposed to use the information from an ongoing study with 3-(trimethoxysilyl)propylamine (EC 237-511-5) |
30/09/2021 30/09/2021 |
15/11/2021 15/11/2021 |
Details | |
Copper(I, II) sulfite | 884-197-6 | 15293-86-4 | 7.6.2 Genetic toxicity in vivo||Note: testing proposed with copper(I,II) sulfite dihydrate (CAS No. 13814-81-8) | 08/03/2024 | 22/04/2024 | Details | |
(chloromethyl)triethoxysilane | 239-311-3 | 15267-95-5 | Genetic toxicity in vivo | 16/10/2014 | 01/12/2014 | Details | |
sodium 1H-benzotriazolide | 239-269-6 | 15217-42-2 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 1H-Benzotriazole (EC 202-394-1) | 16/12/2016 | 30/01/2017 | Details | |