Korábbi/eredmények

Korábbi/eredmények

Korábbi/eredmények

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

There are currently no ongoing consultations.
 
Butene 246-689-3 25167-67-3
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with 2-methylpropene (EC no. 204-066-3)
Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with 2-methylpropene (EC no. 204-066-3)
Sub-chronic toxicity (90 day): inhalation||Note: testing proposed with 2-methylpropene (EC no. 204-066-3)
06/06/2023
06/06/2023
06/06/2023
21/07/2023
21/07/2023
21/07/2023
Details
[1,3(or 1,4)-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide 246-678-3 25155-25-3 Reproductive toxicity (extended one-generation reproductive toxicity study) 27/05/2019 11/07/2019 Details
[1,3(or 1,4)-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide 246-678-3 25155-25-3 Reproductive toxicity (pre-natal developmental toxicity) 30/11/2015 14/01/2016 Details
[1,3(or 1,4)-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide 246-678-3 25155-25-3
Bioaccumulation aquatic / sediment
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
06/03/2012
06/03/2012
06/03/2012
20/04/2012
20/04/2012
20/04/2012
Details
Trixylyl phosphate 246-677-8 25155-23-1 Bioaccumulation aquatic / sediment 02/09/2011 17/10/2011 Details
1,2,3,6-tetrahydromethyl-3,6-methanophthalic anhydride 246-644-8 25134-21-8
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
03/11/2023
03/11/2023
18/12/2023
18/12/2023
Details
tert-dodecanethiol 246-619-1 25103-58-6 Long-term toxicity to fish 16/06/2022 01/08/2022 Details
tert-dodecanethiol 246-619-1 25103-58-6
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
22/06/2017
22/06/2017
07/08/2017
07/08/2017
Details
tert-dodecanethiol 246-619-1 25103-58-6 Sub-chronic toxicity (90 day): inhalation 14/11/2013 30/12/2013 Details
triethoxy(3-isocyanatopropyl)silane 246-467-6 24801-88-5 Genetic toxicity in vivo

Note: testing proposed with 3-(Trimethoxysilyl)propyl isocyanate (EC 239-415-9)
03/02/2016 21/03/2016 Details
Triethoxy(3-isocyanatopropyl)silane 246-467-6 24801-88-5 Genetic toxicity in vivo 18/03/2021 03/05/2021 Details
Strontium bis(2-ethylhexanoate) 219-536-3 2457-02-5 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with [strontium oxide] (EC 215-219-9) 23/11/2020 07/01/2021 Details
1,3,5-Tris(oxiran-2-ylmethyl)-1,3,5-triazinane-2,4,6-trione (TGIC) 219-514-3 2451-62-9 Reproductive toxicity (two-generation reproductive toxicity) 19/11/2010 03/01/2011 Details
2-(2H-benzotriazol-2-yl)-p-cresol 219-470-5 2440-22-4 Bioaccumulation aquatic / sediment 18/06/2018 02/08/2018 Details
Lithium phosphorodifluoridate 643-080-8 24389-25-1 Reproductive toxicity (pre-natal developmental toxicity) 25/05/2020 09/07/2020 Details
tetrasodium 2-(4-fluoro-6-(methyl-(2-(sulfatoethylsulfonyl)ethyl)amino)-1,3,5-triazin-2-ylamino)-5-hydroxy-6-(4-methyl-2-sulfonatophenylazo)naphthalene-1,7-disulfonate 432-550-6 243858-01-7 Genetic toxicity in vivo 30/06/2023 14/08/2023 Details
1,7-Naphthalenedisulfonic acid, 2-[[4-chloro-6-(cyanoamino)-1,3,5-triazin-2-yl]amino]-5-hydroxy-6-[2-[2-methoxy-5-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]diazenyl]-, lithium sodium salt (1:?:?) 440-050-4 243857-97-8 Genetic toxicity in vivo 03/05/2023 19/06/2023 Details
11-aminoundecanoic acid 219-417-6 2432-99-7 Reproductive toxicity (developmental toxicity) 08/04/2010 24/05/2010 Details
11-aminoundecanoic acid 219-417-6 2432-99-7 Long-term toxicity to fish 03/10/2023 17/11/2023 Details
Zinc bis(benzenesulphinate) 246-148-1 24308-84-7 Genetic toxicity in vivo 25/05/2020 09/07/2020 Details
1,4-bis(2,3-epoxypropoxy)butane 219-371-7 2425-79-8
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): most appropriate route
14/02/2011
14/02/2011
14/02/2011
31/03/2011
31/03/2011
31/03/2011
Details
1,4-bis(2,3-epoxypropoxy)butane 219-371-7 2425-79-8 Reproductive toxicity (extended one-generation reproductive toxicity study)|| Note: testing proposed with Reaction products of hexane-1,6-diol with 2-(chloromethyl)oxirane (1:2) (EC 618-939-5) 23/03/2020 07/05/2020 Details
2-Hexyldecan-1-ol 219-370-1 2425-77-6 Reproductive toxicity (two-generation reproductive toxicity) 05/04/2011 20/05/2011 Details
6-(isononanoylamino)hexanoic acid, compound with 2,2',2''-nitrilotriethanol (1:1) 701-138-0 242482-67-3 Reproductive toxicity (pre-natal developmental toxicity) 01/09/2017 16/10/2017 Details
Benzophenone-3,3':4,4'-tetracarboxylic dianhydride 219-348-1 2421-28-5
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
14/08/2014
14/08/2014
28/09/2014
28/09/2014
Details
N-[2-[(2-cyano-4,6-dinitrophenyl)azo]-5-(diethylamino)phenyl]acetamide 246-058-2 24170-60-3 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 23/11/2020 07/01/2021 Details
1,1'-dithiobis[hexahydro-2H-azepin-2-one] 245-910-0 23847-08-7 Reproductive toxicity (pre-natal developmental toxicity) 25/06/2015 10/08/2015 Details
[3-(trimethoxysilyl)propyl]urea 245-904-8 23843-64-3 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Urea, N-(3-silylpropyl)-, Si-(ethoxy and methoxy) derivs., (EC 601-461-6) || Note: Testing proposal is based on concern identified by the registrant 07/07/2020 21/08/2020 Details
3,6,9,12-tetraoxotridecanol 245-883-5 23783-42-8 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 2-(2-(2-methoxyethoxy)ethoxy)ethanol (EC 203-962-1) 21/10/2021 07/12/2021 Details
[3-(triethoxysilyl)propyl]urea 245-876-7 23779-32-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/04/2015
17/04/2015
04/06/2015
04/06/2015
Details
N1,N3‐bis(3‐methylphenyl)‐5‐[(3‐methylphenyl)sulfamoyl]benzene‐1,3‐dicarboxamide 951-483-8 2375645-78-4
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/06/2022
16/06/2022
16/06/2022
01/08/2022
01/08/2022
01/08/2022
Details
2,4,6,8-tetramethylcyclotetrasiloxane 219-137-4 2370-88-9
Sub-chronic toxicity (90-day): oral
-
22/11/2017
22/11/2017
08/01/2018
08/01/2017
Details
2,4,6,8-tetramethylcyclotetrasiloxane 219-137-4 2370-88-9 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/05/2020 09/07/2020 Details
2,4,6,8-tetramethylcyclotetrasiloxane 219-137-4 2370-88-9
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90 day): inhalation
15/09/2011
15/09/2011
15/09/2011
31/10/2011
31/10/2011
31/10/2011
Details
Methyl [3-(trimethoxysilyl)propyl]carbamate 245-659-7 23432-62-4
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
10/03/2017
10/03/2017
10/03/2017
25/04/2017
25/04/2017
25/04/2017
Details
N-[3-(dimethoxymethylsilyl)-2-methylpropyl]ethylenediamine 245-642-4 23410-40-4
Reproductive toxicity (pre-natal developmental toxicity)
Note: Testing proposal is based on concern identified by the registrant. Testing proposed with N-(3-(trimethoxysilyl)propyl)ethylenediamine (EC 217-164-6)
Sub-chronic toxicity (90-day): oral
Note: Testing proposal is based on concern identified by the registrant. Testing proposed with N-(3-(trimethoxysilyl)propyl)ethylenediamine (EC 217-164-6)
25/06/2015
25/06/2015
10/08/2015
10/08/2015
Details
2,2'-[oxybis(methylene)]-bis[2-ethylpropane-1,3-diol] 245-509-0 23235-61-2 Sub-chronic toxicity (90-day): oral 30/09/2015 16/11/2015 Details
2,2'-[oxybis(methylene)]-bis[2-ethylpropane-1,3-diol] 245-509-0 23235-61-2 Reproductive toxicity (developmental toxicity) 26/01/2011 14/03/2011 Details
2,2'-[oxybis(methylene)]-bis[2-ethylpropane-1,3-diol] 245-509-0 23235-61-2 Long-term toxicity to fish 15/01/2024 29/02/2024 Details
2,2'-[OXYBIS(METHYLENE)]BIS[2-ETHYLPROPANE-1,3-DIOL] 245-509-0 23235-61-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
29/04/2016
29/04/2016
13/06/2016
13/06/2016
Details
2,2'-[oxybis(methylene)]bis[2-ethylpropane-1,3-diol] 245-509-0 23235-61-2 Reproductive toxicity (extended one-generation reproductive toxicity study) 26/03/2018 11/05/2018 Details
Octyl octanoate 218-980-5 2306-88-9
Long-term toxicity to fish
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
03/04/2023
03/04/2023
03/04/2023
22/05/2023
22/05/2023
22/05/2023
Details
N,N’-di[3-(p-toluene sulfonyl)oxy]phenyl urea 876-151-9 2292123-68-1
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
03/04/2023
03/04/2023
22/05/2023
22/05/2023
Details
N-phenyl-N-[(trichloromethyl)thio]benzenesulphonamide 218-915-0 2280-49-1
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
18/02/2014
18/02/2014
04/04/2014
04/04/2014
Details
Tetraammonium ethylenediaminetetraacetate 245-022-3 22473-78-5 Sub-chronic toxicity (90 day): inhalation 16/06/2011 01/08/2011 Details
1,1,3,3-tetramethylbutyl 2-ethylperoxyhexanoate 244-894-2 22288-43-3 Genetic toxicity in vivo 10/05/2022 27/06/2022 Details
1,1,3,3-tetramethylbutyl 2-ethylperoxyhexanoate 244-894-2 22288-43-3 Reproductive toxicity (pre-natal developmental toxicity) 03/03/2014 17/04/2014 Details
4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl 218-760-9 2226-96-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
14/08/2014
14/08/2014
28/09/2014
28/09/2014
Details
4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl 218-760-9 2226-96-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/02/2015
16/02/2015
02/04/2015
02/04/2015
Details
butan-2-one O,O',O''-(vinylsilylidyne)trioxime 218-747-8 2224-33-1 Reproductive toxicity (pre-natal developmental toxicity)
Note: testing proposed with Butan-2-one O,O',O''-(methylsilylidyne)trioxime (CAS 22984-54-9).
25/06/2015 10/08/2015 Details
Zinc O,O,O',O'-tetrakis(1,3-dimethylbutyl) bis(phosphorodithioate) 218-679-9 2215-35-2
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) Testing proposed according to a plan for the ZDDP category
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) Testing proposed according to a plan for the ZDDP category.
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) Testing proposed according to a plan for the ZDDP category.“
04/10/2018
04/10/2018
04/10/2018
19/11/2018
19/11/2018
19/11/2018
Details
Zinc O,O,O',O'-tetrakis(1,3-dimethylbutyl) bis(phosphorodithioate) 218-679-9 2215-35-2
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with, zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), and Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), and zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5)
21/12/2021
21/12/2021
21/12/2021
04/02/2022
04/02/2022
04/02/2022
Details
[1,3-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide 218-664-7 2212-81-9
Bioaccumulation aquatic / sediment
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/05/2012
16/05/2012
16/05/2012
02/07/2012
02/07/2012
02/07/2012
Details
[1,3-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide 218-664-7 2212-81-9 Reproductive toxicity (extended one-generation reproductive toxicity study) “|| Note: testing proposed with [1,3(or 1,4)-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide CAS: 25155-25-3)” 25/05/2020 09/07/2020 Details
[1,3-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide 218-664-7 2212-81-9
Bioaccumulation aquatic / sediment
Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant
20/10/2016
20/10/2016
05/12/2016
05/12/2016
Details
2,3-epoxypropyl o-tolyl ether 218-645-3 2210-79-9
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
16/05/2014
16/05/2014
16/05/2014
30/06/2014
30/06/2014
30/06/2014
Details
12-hydroxyoctadecanoic acid, reaction products with 1,3-benzenedimethanamine and hexamethylenediamine 432-840-2 220926-97-6 Repeated dose toxicity: Inhalation 04/05/2010 18/06/2010 Details
S-(3-(triethoxysilyl)propyl)octanethioate 436-690-9 220727-26-4
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
25/09/2012
25/09/2012
25/09/2012
12/11/2012
12/11/2012
12/11/2012
Details
S-(3-(triethoxysilyl)propyl)octanethioate 436-690-9 220727-26-4
Reproductive toxicity (extended one-generation reproductive toxicity study
Reproductive toxicity (pre-natal developmental toxicity)
18/03/2021
18/03/2021
03/05/2021
03/05/2021
Details
1,1'-(isopropylidene)bis[3,5-dibromo-4-(2,3-dibromopropoxy)benzene] 244-617-5 21850-44-2
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
18/09/2014
18/09/2014
03/11/2014
03/11/2014
Details
4-((Triethoxysilyl)methyl) morpholine 480-370-1 21743-27-1
Reproductive toxicity (developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day)
27/11/2009
27/11/2009
27/11/2009
11/01/2010
11/01/2010
11/01/2010
Details
tin monoxide 244-499-5 21651-19-4 Sub-chronic toxicity (90 day): inhalation 23/01/2015 09/03/2015 Details
2-methyl-1,3-propanediol 412-350-5 2163-42-0 Long-term toxicity to fish 15/01/2024 29/02/2024 Details
Bis(2,6-diisopropylphenyl)carbodiimide 218-487-5 2162-74-5 Reproductive toxicity (pre-natal developmental toxicity) 22/09/2022 07/11/2022 Details
N-{2-[(phenylcarbamoyl)amino]phenyl}benzenesulfonamide 806-543-7 215917-77-4 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 30/11/2015 14/01/2016 Details
N-{2-[(phenylcarbamoyl)amino]phenyl}benzenesulfonamide 806-543-7 215917-77-4
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
24/02/2020
24/02/2020
09/04/2020
09/04/2020
Details
Dibutyl itaconate 218-451-9 2155-60-4
Genetic toxicity in vivo
Sub-chronic toxicity (90-day): oral
24/02/2020
24/02/2020
09/04/2020
09/04/2020
Details
Vinyl laurate 218-414-7 2146-71-6 Sub-chronic toxicity (90-day): oral 16/05/2011 30/06/2011 Details
N'-(1,3-dimethylbutylidene)-3-hydroxy-2-naphthohydrazide 435-860-1 214417-91-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/04/2012
17/04/2012
01/06/2012
01/06/2012
Details
N'-(1,3-dimethylbutylidene)-3-hydroxy-2-naphthohydrazide 435-860-1 214417-91-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
25/05/2020
25/05/2020
09/07/2020
09/07/2020
Details
6-(cyclohexylamino)-3-methyl-3H-dibenz[f,ij]isoquinoline-2,7-dione 244-320-0 21295-57-8 Genetic toxicity in vivo 26/08/2021 11/10/2021 Details
2-[(2-methyl-1-oxoallyl)oxy]ethyl acetoacetate 244-311-1 21282-97-3 Genetic toxicity in vivo 29/04/2014 13/06/2014 Details
Fatty acids, C16-C18 and C18-unsatd., ME esters, epoxidized, reaction products with ethylen glycol 606-712-3 211450-54-3 Reproductive toxicity (pre-natal developmental toxicity) 04/04/2014 19/05/2014 Details
2-tert-butyl-1,4-dimethoxybenzene 244-216-5 21112-37-8 Genetic toxicity in vivo 18/03/2021 03/05/2021 Details
Cobalt dihydroxide 244-166-4 21041-93-0
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
Details
Cobalt dihydroxide 244-166-4 21041-93-0
Carcinogenicity || Note: testing proposed with Cobalt dichloride (EC 231-589-4)
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2)
21/01/2021
21/01/2021
08/03/2021
08/03/2021
Details
Diammonium dihydrogen ethylenediaminetetraacetate 244-063-4 20824-56-0 Sub-chronic toxicity (90 day): inhalation 29/07/2011 12/09/2011 Details
8,9,10,11-tetrachloro-12H-phthaloperin-12-one 244-007-9 20749-68-2 Reproductive toxicity (pre-natal developmental toxicity) 14/08/2014 28/09/2014 Details
Disilver oxide 243-957-1 20667-12-3 Sub-chronic toxicity (90-day): oral 15/04/2011 30/05/2011 Details
Tetraammineplatinum dinitrate 243-929-9 20634-12-2 Genetic toxicity in vivo || Note: testing proposed with tetraammineplatinum(II) dichloride. Testing proposal is based on concern identified by the registrant. 28/02/2018 16/04/2018 Details
N-butyl 4-oxopentanoate 218-143-4 2052-15-5
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Levulinic acid (EC 204-649-2)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Levulinic acid (EC 204-649-2)
23/11/2020
23/11/2020
07/01/2021
07/01/2021
Details
triethoxy(methyl)silane 217-983-9 2031-67-6 Sub-chronic toxicity (90-day): oral 25/05/2020 09/07/2020 Details
triethoxy(methyl)silane 217-983-9 2031-67-6 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with trimethoxy(methyl)silane. 16/10/2014 01/12/2014 Details
Sodium 4-oxovalerate 243-378-4 19856-23-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/06/2018
18/06/2018
02/08/2018
02/08/2018
Details
Methanal, reaction products with 1,3-bis(aminomethyl)benzene and hydroxybenzen 701-207-5 1950616-36-0
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
21/05/2018
21/05/2018
21/05/2018
05/07/2018
05/07/2018
05/07/2018
Details
Hexahydro-4-methylphthalic anhydride 243-072-0 19438-60-9 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018 Details
3,3,4,4,5,5,6,6,6-nonafluorohexene 243-053-7 19430-93-4 Sub-chronic toxicity (90 day): inhalation 14/08/2014 28/09/2014 Details
benzyl butyl cis-cyclohexane-1,2-dicarboxylate 701-279-8 1931129-39-3
Long-term toxicity to fish || Note: Link to the registration dossier not given as the dossier not yet disseminated. || Note: this substance was previously registered, identified and disseminated with EC No. 810-685-5
Reproductive toxicity (pre-natal developmental toxicity) || Note: Link to registration dossier not given as the dossier not yet disseminated. || Note: this substance was previously registered, identified and disseminated with EC No. 810-685-5
Sub-chronic toxicity (90-day): oral || Note: Link to registration dossier not given as the dossier not yet disseminated. || Note: this substance was previously registered, identified and disseminated with EC No. 810-685-5
10/12/2018
10/12/2018
10/12/2018
24/01/2019
24/01/2019
24/01/2019
Details
OO-tert-butyl monoperoxymaleate 217-691-1 1931-62-0 Genetic toxicity in vivo 23/11/2020 07/01/2021 Details
A mixture of: triphenylthiophosphate and tertiary butylated phenyl derivatives 421-820-9 192268-65-8 Long-term toxicity to fish||Note: testing proposed with O,O,O-triphenyl phosphorothioate (EC no. 209-909-9) 04/12/2023 18/01/2024 Details
reaction mass of: triphenylthiophosphate and tertiary butylated phenyl derivatives 421-820-9 192268-65-8 Reproductive toxicity (pre-natal developmental toxicity) 16/10/2014 01/12/2014 Details
Di(tetraethylammonium)hexahydroxoplatinate(IV) 848-537-7 1912392-88-1 Genetic toxicity in vivo 21/09/2020 05/11/2020 Details
Potassium hexadecyl hydrogen phosphate 242-768-1 19035-79-1 Reproductive toxicity (pre-natal developmental toxicity) 20/05/2021 05/07/2021 Details
Peroxyacetic acid, reaction products with N2,N2’-1,6-hexanediylbis[N4,N6-dibutyl-N2,N4,N6-tris(2,2,6,6,tetramethyl-4-piperidinyl)-1,3,5-triazine-2,4,6-triamine, hydrogenated 812-927-5 1902936-62-2 Reproductive toxicity (pre-natal developmental toxicity) 10/08/2018 24/09/2018 Details
1,1'-(1,1,2,2-tetramethylethylene)dibenzene 217-568-2 1889-67-4
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/02/2014
18/02/2014
04/04/2014
04/04/2014
Details
N-acetylhexanelactam 217-565-6 1888-91-1 Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant 17/06/2020 03/08/2020 Details
Octacos-1-ene 242-616-4 18835-34-2
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
31/05/2011
31/05/2011
15/07/2011
15/07/2011
Details
Hexacos-1-ene 242-615-9 18835-33-1
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
31/05/2011
31/05/2011
15/07/2011
15/07/2011
Details
(E)-7,11-dimethyl-3-methylenedodeca-1,6,10-triene 242-582-0 18794-84-8 Sub-chronic toxicity (90-day): oral 23/04/2018 07/06/2018 Details
6-tert-butyl-2,4-xylenol 217-533-1 1879-09-0
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
18/02/2021
18/02/2021
05/04/2021
05/04/2021
Details
6-tert-butyl-2,4-xylenol 217-533-1 1879-09-0 Long-term toxicity to fish 15/07/2014 29/08/2014 Details
1,1,1,3,5,5,5-heptamethyltrisiloxane 217-496-1 1873-88-7
Reproductive toxicity (pre-natal developmental toxicity)
Note: testing proposed with Octamethyltrisiloxane, CAS 107-51-7 and 1,1,3,3-tetramethyldisiloxane, CAS 3277-26-7
Sub-chronic toxicity (90 day): inhalation
Note: testing proposed with 1,1,3,3-tetramethyldisiloxane, CAS 3277-26-7.
25/06/2015
25/06/2015
10/08/2015
10/08/2015
Details
Fatty acids, tall-oil, reaction products with bisphenol A, epichlorohydrin, glycidyl tolyl ether and triethylenetetramine 606-078-8 186321-96-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
04/04/2014
04/04/2014
19/05/2014
19/05/2014
Details
3-hydroxy-2-(hydroxymethyl)-2-methylpropanal 242-393-3 18516-18-2
Genetic toxicity in vivo
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/06/2011
16/06/2011
16/06/2011
16/06/2011
01/08/2011
01/08/2011
01/08/2011
01/08/2011
Details
[No public or meaningful name is available] 944-258-0 1850357-57-1 Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Wax, rice bran, oxidized (Polar modified Rice Bran Wax) 03/05/2023 19/06/2023 Details
Strontium hydroxide 242-367-1 18480-07-4
Long-term toxicity to fish Note: testing proposed with strontium dinitrate (EC: 233-131-9, CAS: 10042-76-9)
Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with strontium dinitrate (EC: 233-131-9, CAS: 10042-76-9)
Reproductive toxicity (two-generation reproductive toxicity) Note: testing proposed with strontium dinitrate (EC: 233-131-9, CAS: 10042-76-9)
15/04/2014
15/04/2014
15/04/2014
30/05/2014
30/05/2014
30/05/2014
Details
2,6-dimethyloct-7-en-2-ol 242-362-4 18479-58-8 Reproductive toxicity (pre-natal developmental toxicity) 26/08/2021 11/10/2021 Details
2,6-dimethyloct-7-en-2-ol 242-362-4 18479-58-8 Reproductive toxicity (two-generation reproductive toxicity) 14/02/2011 31/03/2011 Details
2,6-dimethyloct-7-en-2-ol 242-362-4 18479-58-8 Reproductive toxicity (extended one-generation reproductive toxicity study) 01/09/2017 16/10/2017 Details
2,6-dimethyloct-7-en-2-ol 242-362-4 18479-58-8 Long-term toxicity to fish 03/10/2023 17/11/2023 Details
Octabenzone 217-421-2 1843-05-6 Reproductive toxicity (pre-natal developmental toxicity) 18/02/2013 04/04/2013 Details
(3-chloropropyl)dimethoxymethylsilane 242-056-0 18171-19-2 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with (3-chloropropyl)triethoxysilane (EC 225-805-6)” 17/04/2015 04/06/2015 Details
(3-chloropropyl)dimethoxymethylsilane 242-056-0 18171-19-2 Sub-chronic toxicity (90-day): oral 25/05/2020 09/07/2020 Details
1,2-diacetoxybut-3-ene 421-720-5 18085-02-4 Sub-chronic toxicity (90-day): oral 25/11/2021 10/01/2022 Details
1,1,1,3,5,5,5-heptamethyl-3-octyltrisiloxane 241-881-3 17955-88-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/06/2020
17/06/2020
03/08/2020
03/08/2020
Details
1,1,1,3,5,5,5-heptamethyl-3-[(trimethylsilyl)oxy]trisiloxane 241-867-7 17928-28-8 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with decamethyltetrasiloxane (EC no. 205-491-7, CAS no. 141-62-8) 12/12/2014 26/01/2015 Details
2,4,7,9-tetramethyl-4,7-decanediol 451-160-7 17913-76-7
Long-term toxicity to fish
"|| Note: testing proposed with 2,4,7,9-tetramethyldec-5-yne-4,7-diol (EC 204-809-1, CAS 126-86-3)
Reproductive toxicity (pre-natal developmental toxicity)
17/09/2019
17/09/2019
01/11/2019
01/11/2019
Details
N-(cyclohexylthio)phthalimide 241-774-1 17796-82-6
Bioaccumulation: aquatic / sediment
Long-term or reproductive toxicity to birds
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
01/07/2011
01/07/2011
01/07/2011
01/07/2011
17/12/2012
15/08/2011
15/08/2011
15/08/2011
15/08/2011
31/01/2013
Details
3-hydroxy-2-(3-hydroxy-2-quinolyl)-1H-inden-1-one 241-753-7 17772-51-9 Reproductive toxicity (pre-natal developmental toxicity) 31/08/2015 15/10/2015 Details
1,3,5-triazine-2,4,6(1H,3H,5H)-trithione, trisodium salt 241-749-5 17766-26-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
14/08/2014
14/08/2014
28/09/2014
28/09/2014
Details
Sodium hydrogen m-sulphonatobenzoate 241-602-5 17625-03-5
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
03/04/2023
03/04/2023
22/05/2023
22/05/2023
Details
N-(3-(trimethoxysilyl)propyl)ethylenediamine 217-164-6 1760-24-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
03/03/2014
03/03/2014
17/04/2014
17/04/2014
Details
Aminoiminomethanesulphinic acid 217-157-8 1758-73-2
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
16/05/2014
16/05/2014
30/06/2014
30/06/2014
Details
N,N''-(4-methyl-m-phenylene)bis[N',N'-dimethylurea] 241-523-6 17526-94-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
23/03/2020
23/03/2020
07/05/2020
07/05/2020
Details
p-tert-butylstyrene 217-126-9 1746-23-2 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant. 25/05/2020 09/07/2020 Details
2-Hydroxy-5-nonyl(branched)-benzaldehyde oxime 605-717-8 174333-80-3 Long-term toxicity to fish 22/06/2017 07/08/2017 Details
1,2-dimethylimidazole 217-101-2 1739-84-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
19/10/2020
19/10/2020
03/12/2020
03/12/2020
Details
1,2-dimethylimidazole 217-101-2 1739-84-0
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
10/05/2022
10/05/2022
27/06/2022
27/06/2022
Details
3,4-dihydroxybenzonitrile 241-367-9 17345-61-8 Genetic toxicity in vivo 17/06/2020 03/08/2020 Details
Barium hydroxide 241-234-5 17194-00-2
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
16/12/2011
16/12/2011
30/01/2012
30/01/2012
Details
Barium hydroxide 241-234-5 17194-00-2 Long-term toxicity to fish 29/04/2011 14/06/2011 Details
Barium hydroxide 241-234-5 17194-00-2 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Barium chloride dihydrate (EC 600-412-6) 16/12/2020 01/02/2021 Details
chlorodimethylvinylsilane 217-007-1 1719-58-0 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Trimethylsilanol (CAS 1066-40-6) 12/12/2014 26/01/2015 Details
Lithium bis(fluorosulfonyl)imide 686-526-7 171611-11-3
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
21/10/2021
21/10/2021
21/10/2021
07/12/2021
07/12/2021
07/12/2021
Details
N-(2-ethylhexyl)isononan-1-amide 810-288-7 1700656-13-8
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
26/08/2021
26/08/2021
11/10/2021
11/10/2021
Details
Hexachloroplatinic acid 241-010-7 16941-12-1 Genetic toxicity in vivo || Note: testing proposed with Diammonium hexachloroplatinate (EC 241-010-7). Testing proposal is based on concern identified by the registrant. 26/03/2018 11/05/2018 Details
dipotassium heptafluorotantalate 240-986-1 16924-00-8 Genetic toxicity in vivo 16/03/2015 30/04/2015 Details
Dipotassium hexachloroplatinate 240-979-3 16921-30-5 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 26/03/2018 11/05/2018 Details
Diammonium hexachloroplatinate 240-973-0 16919-58-7 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 23/04/2018 07/06/2018 Details
1,3-Butanediol, reaction products with 1,1'-methylenebis[4-isocyanatobenzene], propylene glycol and tripropylene glycol 941-496-7 1689576-89-3 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC 202-966-0) 01/04/2022 16/05/2022 Details
benzyl 3-isobutyryloxy-1-isopropyl-2,2-dimethylpropyl phthalate 240-920-1 16883-83-3
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
16/06/2011
16/06/2011
01/08/2011
01/08/2011
Details
Dimethoxymethylsilane 240-914-9 16881-77-9 Sub-chronic toxicity (90-day): oral 25/05/2020 09/07/2020 Details
dimethoxymethylsilane 240-914-9 16881-77-9 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with trimethoxy(methyl)silane. 16/10/2014 01/12/2014 Details
1,5-bis[1,2-bis(ethoxycarbonyl)ethylamino]-2-methylpentane 433-260-2 168253-59-6
Reproductive toxicity (developmental toxicity)
Sub-chronic toxicity (90-day): oral
06/09/2010
06/09/2010
20/10/2010
20/10/2010
Details
diammonium hexanitratocerate 240-827-6 16774-21-3 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Cerium (III) nitrate (CAS 10294-41-4) 20/05/2015 06/07/2015 Details
1-methyl-4-(methylsulfonyl)-2-nitrobenzene 430-550-0 1671-49-4 Genetic toxicity in vivo 16/05/2011 30/06/2011 Details
potassium 4-cumenesulfonate 629-764-9 164524-02-1 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Sodium xylene sulphonate (EC 215-090-9) 16/12/2016 30/01/2017 Details
potassium 4-cumenesulfonate 629-764-9 164524-02-1
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with sodium (xylenes and 4-ethylbenzene) sulphonate
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with sodium cumene sulphonate  
22/06/2017
22/06/2017
07/08/2017
07/08/2017
Details
potassium 4-isopropylbenzenesulphonate 629-764-9 164524-02-1 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/06/2015 10/08/2015 Details
3-((C12-18)-acylamino)-N-(2-((2-hydroxyethyl)amino)-2-oxoethyl)-N,N-dimethyl-1-propanaminium chloride 427-370-1 164288-56-6 Reproductive toxicity (extended one-generation reproductive toxicity study) 03/04/2023 22/05/2023 Details
Triethoxyhexadecylsilane 240-465-9 16415-13-7
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Hexadecyltrimethoxysilane (EC 240-464-3) || Note: Testing proposal is based on concern identified by the registrant
Sub-chronic toxicity (90-day): oral
07/07/2020
07/07/2020
21/08/2020
21/08/2020
Details
hexadecyltrimethoxysilane 240-464-3 16415-12-6 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/05/2020 09/07/2020 Details
hexadecyltrimethoxysilane 240-464-3 16415-12-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/10/2014
16/10/2014
01/12/2014
01/12/2014
Details
hexadecyltrimethoxysilane 240-464-3 16415-12-6
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
25/11/2021
25/11/2021
10/01/2022
10/01/2022
Details
Reaction mass of (2S-cis)-tetrahydro-4-methyl-2-(2-methyl-1-propenyl)-2H-pyran and Tetrahydro-4-methyl-2-(2-methylpropen-1-yl)pyran (2R,4R) and Tetrahydro-4-methyl-2-(2-methylpropen-1-yl)pyran (2S,4S) and (2R-cis)-tetrahydro-4-methyl-2-(2-methyl-1-propenyl)-2H-pyran 939-429-1 16409-43-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
30/11/2015
30/11/2015
14/01/2016
14/01/2016
Details
3-(Trimethoxysilyl)propyl (2E,4E)-hexa-2,4-dienoate 642-902-2 163802-53-7 Genetic toxicity in vivo 10/03/2017 25/04/2017 Details
Strontium carbonate 216-643-7 1633-05-2 Long-term toxicity to fish 31/05/2011 15/07/2011 Details
Hexamethylene diisocyanate, oligomerisation product, blocked with 3,5-dimethyl-1H-pyrazole 605-318-9 163206-31-3 Sub-chronic toxicity (90 day): inhalation 12/12/2014 26/01/2015 Details
Phenyl bis(2,4,6-trimethylbenzoyl)-phosphine oxide 423-340-5 162881-26-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
22/12/2010
22/12/2010
22/12/2010
07/02/2011
07/02/2011
07/02/2011
Details
Condensation products of dimerised fatty acids, C18-unsaturated, with N,N-dimethyl-1,3-propanediamine and 1,3-propanediamine 605-296-0 162627-17-0
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90 day): oral
14/08/2014
14/08/2014
14/08/2014
28/09/2014
28/09/2014
28/09/2014
Details
(Z)-N-octadec-9-enylhexadecan-1-amide 240-367-6 16260-09-6 Reproductive toxicity (pre-natal developmental toxicity) 14/08/2014 28/09/2014 Details
Tris(2,5,8,11-tetraoxatridecyl) orthoborate 310-290-3 161907-80-8
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/09/2011
15/09/2011
15/09/2011
31/10/2011
31/10/2011
31/10/2011
Details
2,2-dimethyl-3-oxopropyl acetate 811-188-6 16184-79-5 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 01/09/2017 16/10/2017 Details
Bis(2-ethylhexyl) peroxydicarbonate 240-282-4 16111-62-9
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/04/2014
15/04/2014
30/05/2014
30/05/2014
Details
Hexafluoropropene, oxidized, oligomers, reduced, fluorinated 500-537-5 161075-00-9 Bioaccumulation aquatic / sediment 16/10/2014 01/12/2014 Details
1,6-bis(2,3-epoxypropoxy)hexane 240-260-4 16096-31-4
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): dermal
15/03/2011
15/03/2011
15/03/2011
29/04/2011
29/04/2011
29/04/2011
Details
1,6-bis(2,3-epoxypropoxy)hexane 240-260-4 16096-31-4
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): dermal
15/09/2011
15/09/2011
15/09/2011
31/10/2011
31/10/2011
31/10/2011
Details
Fatty acids, tall oil, oligomeric reaction products with maleic anhydride and rosin, calcium magnesium zinc salts, consisting of mainly calcium, magnesium, zinc salts of maleated rosin, fatty acids and rosin 500-451-8 160901-14-4
Reproductive toxicity (pre-natal developmental toxicity) //Note: to be tested with Rosin, maleated (CAS RN 8050-28-0)
Reproductive toxicity (two-generation reproductive toxicity) //Note: Testing proposed with Rosin, Fumarated (CAS RN 65997-04-7)
Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin, fumarated (CAS RN 65997-04-7) and Rosin, maleated (CAS RN 8050-28-0)
02/07/2013
02/07/2013
02/07/2013
16/08/2013
16/08/2013
16/08/2013
Details
Fatty acids, tall-oil, oligomeric reaction products with maleic anhydride and rosin, calcium magnesium zinc salts 500-451-8 160901-14-4 Reproductive toxicity (pre-natal developmental toxicity) 06/03/2012 20/04/2012 Details
4,4,7,7-tetraethoxy-3,8-dioxa-4,7-disiladecane 240-212-2 16068-37-4
Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/06/2020
17/06/2020
17/06/2020
17/06/2020
03/08/2020
03/08/2020
03/08/2020
03/08/2020
Details
1-hydroxy-4-[[4-[(methylsulphonyl)oxy]phenyl]amino]anthraquinone 216-475-4 1594-08-7 Genetic toxicity in vivo 01/07/2021 16/08/2021 Details
Triammonium hydrogen ethylenediaminetetraacetate 240-073-8 15934-01-7 Sub-chronic toxicity (90 day): inhalation 16/06/2011 01/08/2011 Details
A mixture of: bis[4-diphenylsulfoniumphenyl]sulfide-bishexafluoroantimonate; thiophenoxyphenylsulfonium hexafluoroantimonate 403-500-0 159120-95-3 Genetic toxicity in vivo 03/10/2023 17/11/2023 Details
Propylidynetrimethanol, ethoxylated, esters with acrylic acid, reaction products with diethylamine 500-425-6 159034-91-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
26/08/2021
26/08/2021
11/10/2021
11/10/2021
Details
Propylidynetrimethanol, ethoxylated, esters with acrylic acid, reaction products with diethylamine 500-425-6 159034-91-0 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 16/12/2020 01/02/2021 Details
2,2-bis[[(1-oxopentyl)oxy]methyl]propane-1,3-diyl divalerate 239-937-7 15834-04-5 Reproductive toxicity (extended one-generation reproductive toxicity study) 21/10/2019 05/12/2019 Details
Fatty acids, C16-C18 and C18-unsatd., ME esters, epoxidized 605-143-8 158318-67-3 Reproductive toxicity (pre-natal developmental toxicity) 16/05/2014 30/06/2014 Details
Tri(isopropyl)silyl acrylate 457-670-6 157859-20-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
31/08/2015
31/08/2015
15/10/2015
15/10/2015
Details
Tri(isopropyl)silyl acrylate 457-670-6 157859-20-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
31/08/2015
31/08/2015
15/10/2015
15/10/2015
Details
sodium cumenesulphonate 239-854-6 15763-76-5 Reproductive toxicity (extended one-generation reproductive toxicity study) 16/12/2016 30/01/2017 Details
Sodium p-cumenesulphonate 239-854-6 15763-76-5
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Sodium (xylenes and 4-ethylbenzene) sulphonate
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with sodium cumene sulphonate
22/06/2017
22/06/2017
07/08/2017
07/08/2017
Details
sodium p-cumenesulphonate 239-854-6 15763-76-5 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Sodium xylene sulphonate 24/04/2015 12/06/2015 Details
Alcohols, C16-18 and C18-unsatd., ethoxylated, sulfates, sodium salts 500-345-1 157627-95-7 Reproductive toxicity (pre-natal developmental toxicity) 30/06/2023 14/08/2023 Details
Disodium; 4-Amino-3-{4-[4-(2,4-diamino-phenylazo)-benzenesulfonylamino]-phenylazo}-5-hydroxy-6-phenylazo-naphthalene-2,7-disulfonate 605-104-5 157577-99-6 Genetic toxicity in vivo 26/08/2021 11/10/2021 Details
bis(4-(1,1,3,3-tetramethylbutyl)phenyl)amine 239-816-9 15721-78-5
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
18/02/2014
18/02/2014
18/02/2014
04/04/2014
04/04/2014
04/04/2014
Details
1,4-Benzenedicarboxylic acid, mixed Bu and 2-ethylhexyl diesters 946-149-3 1571954-81-8
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
21/05/2018
21/05/2018
05/07/2018
05/07/2018
Details
[1R-(1α,2β,5α)]-1-(isopropyl)-2-methoxy-4-methylcyclohexane 216-365-6 1565-76-0 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 19/10/2020 03/12/2020 Details
2-ethyl-2-[[(1-oxoallyl)oxy]methyl]-1,3-propanediyl diacrylate; 2,2-bis(acryloyloxymethyl)butyl acrylate; trimethylolpropane triacrylate 239-701-3 15625-89-5
Reproductive toxicity (extended one-generation reproductive toxicity study)
Sub-chronic toxicity (90-day): oral
25/05/2020
25/05/2020
09/07/2020
09/07/2020
Details
2-ethyl-2-[[(1-oxoallyl)oxy]methyl]-1,3-propanediyl diacrylate; 2,2-bis(acryloyloxymethyl)butyl acrylate; trimethylolpropane triacrylate 239-701-3 15625-89-5 Reproductive toxicity (extended one-generation reproductive toxicity study) 26/10/2022 12/12/2022 Details
Cobalt(2+) propionate 216-333-1 1560-69-6
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
Details
Calcium cyanamide 205-861-8 156-62-7 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018 Details
calcium cyanamide 205-861-8 156-62-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/04/2011
15/04/2011
30/05/2011
30/05/2011
Details
2,2'-azobis[4-methoxy-2,4-dimethylvaleronitrile] 239-593-8 15545-97-8 Genetic toxicity in vivo 17/06/2020 03/08/2020 Details
Diphosphoric acid, compound with 1,3,5-triazine-2,4,6-triamine 239-590-1 15541-60-3 Reproductive toxicity (pre-natal developmental toxicity) 26/08/2021 11/10/2021 Details
bis(4-tert-butylcyclohexyl) peroxydicarbonate 239-557-1 15520-11-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2014
15/07/2014
29/08/2014
29/08/2014
Details
2,2'-(octylimino)bisethanol 239-555-0 15520-05-5
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
25/11/2019
25/11/2019
09/01/2020
09/01/2020
Details
3-(trimethoxysilyl)propyl isocyanate 239-415-9 15396-00-6
Genetic toxicity in vivo
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: it is proposed to use the information from an ongoing study with 3-(trimethoxysilyl)propylamine (EC 237-511-5)
30/09/2021
30/09/2021
15/11/2021
15/11/2021
Details
Copper(I, II) sulfite 884-197-6 15293-86-4 7.6.2 Genetic toxicity in vivo||Note: testing proposed with copper(I,II) sulfite dihydrate (CAS No. 13814-81-8) 08/03/2024 22/04/2024 Details
(chloromethyl)triethoxysilane 239-311-3 15267-95-5 Genetic toxicity in vivo 16/10/2014 01/12/2014 Details
sodium 1H-benzotriazolide 239-269-6 15217-42-2 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 1H-Benzotriazole (EC 202-394-1) 16/12/2016 30/01/2017 Details