Korábbi/eredmények

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

2 011 eredményből 601 - 800 megmutatása.

Name	EC Number	CAS Number	Hazard endpoint for which vertebrate testing was proposed	Date of publication to call for available information	Deadline for submitting information
A mixture of: esters of C14-C15 branched alcohols with 3,5-di-t-butyl-4-hydroxyphenyl propionic acid; C15 branched and linear alkyl 3,5-bis(1,1-dimethylethyl)-4-hydroxybenzenepropanoate; C13 branched and linear alkyl 3,5-bis(1,1-dimethylethyl)-4-hydroxybenzenepropanoate	413-750-2	-	Reproductive toxicity (pre-natal developmental toxicity)	30/09/2021	15/11/2021	Details
2-methyl-1,3-propanediol	412-350-5	2163-42-0	Long-term toxicity to fish	15/01/2024	29/02/2024	Details
1-[(2-tert-butylcyclohexyl)oxy]butan-2-ol	412-300-2	-	Reproductive toxicity (pre-natal developmental toxicity)	18/02/2021	05/04/2021	Details
1-acetyl-4-(3-dodecyl-2,5-dioxo-1-pyrrolidinyl)-2,2,6,6-tetramethylpiperidine	411-930-5	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	28/11/2022 28/11/2022	12/01/2023 12/01/2023	Details
1,6-hexanediyl-bis(2-(2-(1-ethylpentyl)-3-oxazolidinyl)ethyl)carbamate	411-700-4	140921-24-0	Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	10/05/2022 10/05/2022 10/05/2022	27/06/2022 27/06/2022 27/06/2022	Details
Reaction mass of 2,5-bis(isocyanatomethyl)-bicyclo[2.2.1]heptane and 2,6-bis(isocyanatomethyl)-bicyclo[2.2.1]heptane	411-280-2	-	Genetic toxicity in vivo	16/07/2012	30/08/2012	Details
2,4-dimethyl-6-(1-methyl-pentadecyl)phenol	411-220-5	-	Reproductive toxicity (pre-natal developmental toxicity)	25/09/2012	12/11/2012	Details
A mixture of: tetrasodium-phosphonoethane-1,2-dicarboxylate,hexasodium-phosphonobutane-1,2,3,4-tetracarboxylate	410-800-5	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	06/03/2012 06/03/2012	20/04/2012 20/04/2012	Details
Reaction products of 2-(4,6-bis(2,4-dimethylphenyl)-1,3,5-triazin-2-yl)-5-hydroxy phenol with ((C10-16, rich in C12-13 alkyloxy)methyl)oxyrane	410-560-1	-	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity)	16/01/2012 16/01/2012	01/03/2012 01/03/2012	Details
Bis(4-methylbenzoyl)peroxide	407-950-9	895-85-2	6.1.2 Long-term toxicity to fish\|\|Note: testing proposed with p-toluic acid (EC no. 202-803-3) or with bis(4-methylbenzoyl) peroxide (EC no. 407-905-9)	08/03/2024	22/04/2024	Details
4,4'-(9H-fluoren-9-ylidene)bis(2-chloroaniline)	407-560-9	107934-68-9	Bioaccumulation aquatic / sediment \|\| Note: Testing proposal is based on concern identified by the registrant.	16/10/2014	01/12/2014	Details
4,4'-(9H-fluoren-9-ylidene)bis(2-chloroaniline)	407-560-9	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	17/06/2020 17/06/2020	03/08/2020 03/08/2020	Details
Reaction mass of bis(2,2,6,6-tetramethyl-1-octyloxypiperidin-4-yl)-1,10-decanedioate and 1,8-bis[(2,2,6,6-tetramethyl-4-((2,2,6,6-tetramethyl-1-octyloxypiperidin-4-yl)-decan-1,10-dioyl)piperidin-1-yl)oxy]octane	406-750-9	-	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity)	04/06/2012 04/06/2012	19/07/2012 19/07/2012	Details
4-(4-isopropoxyphenylsulfonyl)phenol	405-520-5	95235-30-6	Reproductive toxicity (pre-natal developmental toxicity)	24/08/2020	08/10/2020	Details
A mixture of: cis-tetrahydro-2-isobutyl-4-methylpyran-4-ol; trans-tetrahydro-2-isobutyl-4-methylpyran-4-ol	405-040-6	63500-71-0	Reproductive toxicity (extended one-generation reproductive toxicity study)	25/06/2015	10/08/2015	Details
a mixture of: cistetrahydro-2-isobutyl-4-methylpyran-4-ol,transtetrahydro-2-isobutyl-4-methylpyran-4-ol	405-040-6	63500-71-0	(90-day): oral Reproductive toxicity (developmental toxicity) Sub-chronic toxicity	20/10/2010 20/10/2010 20/10/2010	06/12/2010 06/12/2010 06/12/2010	Details
Dicyclopentyldimethoxysilane	404-370-8	-	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	16/12/2011 16/12/2011 16/12/2011	30/01/2012 30/01/2012 30/01/2012	Details
2-benzyl-2-dimethylamino-4'-morpholinobutyrophenone	404-360-3	-	Reproductive toxicity (pre-natal developmental toxicity)	24/05/2013	08/07/2013	Details
Tetrakis(phenylmethyl)thioperoxydi(carbothioamide)	404-310-0	10591-85-2	Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	30/09/2021 30/09/2021 30/09/2021	15/11/2021 15/11/2021 15/11/2021	Details
2-ethoxyethyl-2-(4-(2,6-dihydro-2,6-dioxo-7-phenyl-1,5-dioxaindacen-3-yl)phenoxy)acetate	403-960-2	-	Genetic toxicity in vivo	03/10/2023	17/11/2023	Details
6'-(dibutylamino)-3'-methyl-2'-(phenylamino)spiro[isobenzofuran-1(3H),9-(9H)-xanthen]-3-one	403-830-5	89331-94-2	Bioaccumulation aquatic / sediment	12/06/2015	27/07/2015	Details
6'-(dibutylamino)-3'-methyl-2'-(phenylamino)spiro[isobenzofuran-1(3H),9-(9H)-xanthen]-3-one	403-830-5	89331-94-2	Sub-chronic toxicity (90-day): oral	26/03/2018	11/05/2018	Details
6'-(dibutylamino)-3'-methyl-2'-(phenylamino)spiro[isobenzofuran-1(3H),9-(9H)-xanthen]-3-one	403-830-5	89331-94-2	Sub-chronic toxicity (90-day): oral	02/09/2013	18/10/2013	Details
6'-(dibutylamino)-3'-methyl-2'-(phenylamino)spiro[isobenzofuran-1(3H),9-(9H)-xanthen]-3-one	403-830-5	89331-94-2	Bioaccumulation aquatic / sediment Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	23/04/2018 23/04/2018 23/04/2018	07/06/2018 07/06/2018 07/06/2018	Details
Calcium 4-chloro-2-(5-hydroxy-3-methyl-1-(3-sulfonatophenyl)pyrazol-4-ylazo)-5-methylbenzenesulfonate	403-530-4	129423-54-7	7.8.2 Developmental toxicity / teratogenicity	08/03/2024	22/04/2024	Details
A mixture of: bis[4-diphenylsulfoniumphenyl]sulfide-bishexafluoroantimonate; thiophenoxyphenylsulfonium hexafluoroantimonate	403-500-0	159120-95-3	Genetic toxicity in vivo	03/10/2023	17/11/2023	Details
O,O-di(1-methylethyl)trithio-bis-thioformate,O,O-di(1-methylethyl)tetrathio-bis-thioformate,O,O-di(1-methylethyl)pentathio-bis-thioformate	403-030-6	-	Reproductive toxicity (pre-natal developmental toxicity)	24/05/2013	08/07/2013	Details
pentasodium 5-{[4-chloro-6-({4-[2-(sulfooxy)ethanesulfonyl]phenyl}amino)-1,3,5-triazin-2-yl]amino}-3-[2-(1,5-disulfonaphthalen-2-yl)diazen-1-yl]-4-hydroxynaphthalene-2,7-disulfonate	402-420-3	89157-03-9	Sub-chronic toxicity (90-day): oral	25/06/2019	09/08/2019	Details
Cyclohexyldimethoxymethylsilane	402-140-1	-	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	16/01/2012 16/01/2012 16/01/2012	01/03/2012 01/03/2012 01/03/2012	Details
Benzenamine, 4,4'-methylenebis[3-chloro-2,6-diethyl-	402-130-7	106246-33-7	Reproductive toxicity (pre-natal developmental toxicity)	01/04/2022	16/05/2022	Details
3-(dimethylamino)propylurea	401-950-2	31506-43-1	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	06/06/2023 06/06/2023	21/07/2023 21/07/2023	Details
A mixture of cis- and trans-cyclohexadec-8-en-1-one	401-700-2	3100-36-5	Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	28/11/2022 28/11/2022 28/11/2022	12/01/2023 12/01/2023 12/01/2023	Details
Diamminediisocyanatozinc	401-610-3	122012-52-6	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity)	10/05/2022 10/05/2022	27/06/2022 27/06/2022	Details
3,6-bis(4-chlorophenyl)-1H,2H,4H,5H-pyrrolo[3,4-c]pyrrole-1,4-dione	401-540-3	-	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	26/03/2018 26/03/2018 26/03/2018	11/05/2018 11/05/2018 11/05/2018	Details
Butyl (dialkyloxy(dibutoxyphosphoryloxy))titanium(trialkyloxy)titanium phosphate	401-100-0	-	Sub-chronic toxicity (90-day): oral	27/05/2019	11/07/2019	Details
A mixture of: α-3-(3-(2H-benzotriazol-2-yl)-5-tert-butyl-4-hydroxyphenyl)propionyl-ω-hydroxypoly(oxyethylene),α-3-(3-(2H-benzotriazol-2-yl)-5-tert-butyl-4-hydroxyphenyl)propionyl-ω-3-(3-(2H-benzotriazol-2-yl)-5-tert-butyl-4-hydroxyphenyl)propionyloxypoly(oxyethylene)	400-830-7	-	Reproductive toxicity (pre-natal developmental toxicity)	16/12/2011	30/01/2012	Details
Tris(2,5,8,11-tetraoxatridecyl) orthoborate	310-290-3	161907-80-8	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	15/09/2011 15/09/2011 15/09/2011	31/10/2011 31/10/2011 31/10/2011	Details
Benzenamine, reaction products with aniline hydrochloride and nitrobenzene, hydrochlorides	309-913-1	101357-16-8	Sub-chronic toxicity (90-day): oral	21/09/2020	05/11/2020	Details
Tar, brown-coal, low-temp.	309-886-6	101316-84-1	Sub-chronic toxicity (90-day): oral	29/07/2011	12/09/2011	Details
Residues (petroleum), vacuum distn. residue hydrogenation	309-713-4	100684-40-0	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity)	16/08/2011 16/08/2011	30/09/2011 30/09/2011	Details
Residues (petroleum), distn. residue hydrogenation	309-712-9	100684-39-7	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity)	16/08/2011 16/08/2011	30/09/2011 30/09/2011	Details
Octadecanoic acid, 12-hydroxy-, reaction products with ethylenediamine	309-629-8	100545-48-0	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): inhalation	16/05/2014 16/05/2014	30/06/2014 30/06/2014	Details
d-Glucose, ether with glycerol	309-496-6	100402-60-6	Reproductive toxicity (pre-natal developmental toxicity)	15/07/2014	29/08/2014	Details
2-Oxetanone, 3-C14-16-alkyl 4-C15-17-alkylidene derivs.	308-760-8	98246-87-8	Long-term toxicity to fish	22/09/2022	07/11/2022	Details
Alkenes, C7-9, hydroformylation products, distn. residues, heavy cracked fraction	308-482-7	98072-31-2	Reproductive toxicity (extended one-generation reproductive toxicity study)	02/11/2018	17/12/2018	Details
Alkenes, C7-9, hydroformylation products, distn. residues, heavy cracked fraction	308-482-7	98072-31-2	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity)	01/08/2011 01/08/2011	15/09/2011 15/09/2011	Details
Ethanol, 2,2'-iminobis-, N-(C13-15-branched and linear alkyl) derivs.	308-208-6	97925-95-6	Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity)	29/07/2011 29/07/2011	12/09/2011 12/09/2011	Details
Ethanol, 2,2'-iminobis-, N-(C13-15-branched and linear alkyl) derivs.	308-208-6	97925-95-6	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed on rabbits	14/08/2014	28/09/2014	Details
2-Propanol, 1,1'-[[3-[(3-aminopropyl)amino]propyl]imino]bis-, N-tallow alkyl derivs	307-276-4	97592-79-5	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/08/2011 16/08/2011	30/09/2011 30/09/2011	Details
Resin acids and Rosin acids, fumarated, esters with glycerol	307-051-0	97489-11-7	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral //Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7), Resin acids and Rosin acids, fumarated, esters with pentaerythritol (CAS RN 94581-15-4), and Rosin acids and resin acids, maleated, esters with pentaerythritol (CAS RN 94581-17-6)	19/07/2013 19/07/2013	02/09/2013 02/09/2013	Details
1,1'-(isopropylidene)bis[3,5-dibromo-4-(2,3-dibromo-2-methylpropoxy)benzene]	306-832-3	97416-84-7	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	01/07/2021 01/07/2021	16/08/2021 16/08/2021	Details
Dodecene, branched	306-479-5	97280-83-6	Reproductive toxicity (extended one-generation reproductive toxicity study)\|\|Note: testing proposed with Butene, homopolymer (products derived from either/or But-1-ene/But-2-ene), branched (EC no. 500-004-7) Reproductive toxicity (pre-natal developmental toxicity)\|\|Note: testing proposed with Butene, homopolymer (products derived from either/or But-1-ene/But-2-ene), branched (EC no. 500-004-7) Sub-chronic toxicity (90-day): oral\|\|Note: testing proposed with Butene, homopolymer (products derived from either/or But-1-ene/But-2-ene), branched (EC no. 500-004-7)	06/06/2023 06/06/2023 06/06/2023	21/07/2023 21/07/2023 21/07/2023	Details
Soybean oil, epoxidized, Me ester, reaction products with propylene glycol	306-246-8	96690-51-6	Genetic toxicity in vivo	18/03/2021	03/05/2021	Details
Amines, C12-14-tert-alkyl, mixed sec-Bu and iso-Bu phosphates	306-227-4	96690-34-5	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with Amines, C11-14-branched alkyl, monohexyl and dihexyl phosphates (EC 279-632-6) \|\| Note: Testing proposal is based on concern identified by the registrant.	23/11/2020	07/01/2021	Details
Fatty acids, C8-10, C12-18-alkyl esters	306-082-7	95912-86-0	Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	01/04/2022 01/04/2022 01/04/2022	16/05/2022 16/05/2022 16/05/2022	Details
Hydrocarbons, C4, 1,3-butadiene- and isobutene-free	306-004-1	95465-89-7	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): inhalation	06/06/2023 06/06/2023 06/06/2023	21/07/2023 21/07/2023 21/07/2023	Details
Rosin, fumarated, reaction products with formaldehyde	305-795-0	95009-65-7	Reproductive toxicity (pre-natal developmental toxicity) //Note: to be tested with Rosin, maleated (CAS RN 8050-28-0). Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin, fumarated (CAS RN 65997-04-7) and Rosin, maleated (CAS RN 8050-28-0)	02/07/2013 02/07/2013	16/08/2013 16/08/2013	Details
Rosin, fumarated, reaction products with formaldehyde	305-795-0	95009-65-7	Reproductive toxicity (pre-natal developmental toxicity)	06/03/2012	20/04/2012	Details
Resin acids and Rosin acids, maleated, esters with pentaerythritol	305-516-2	94581-17-6	Reproductive toxicity (pre-natal developmental toxicity) //Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7) Sub-chronic toxicity (90-day): oral //Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7), Resin acids and Rosin acids, fumarated, esters with pentaerythritol (CAS RN 94581-15-4), and Rosin acids and resin acids, maleated, esters with pentaerythritol (CAS RN 94581-17-6)	19/07/2013 19/07/2013	02/09/2013 02/09/2013	Details
Resin acids and Rosin acids, fumarated, esters with pentaerythritol	305-514-1	94581-15-4	Reproductive toxicity (pre-natal developmental toxicity) //Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: Testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7) Reproductive toxicity (two-generation reproductive toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral //Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7), Resin acids and Rosin acids, fumarated, esters with pentaerythritol (CAS RN 94581-15-4), and Rosin acids and resin acids, maleated, esters with pentaerythritol (CAS RN 94581-17-6) Sub-chronic toxicity (90-day): oral \|\| Note: Testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7), Resin acids and Rosin acids, fumarated, esters with pentaerythritol (CAS RN 94581-15-4), Rosin acids and resin acids, maleated, esters with pentaerythritol (CAS RN 94581-17-6)	19/07/2013 02/07/2013 02/07/2013 19/07/2013 19/07/2013 02/07/2013	02/09/2013 16/08/2013 16/08/2013 02/09/2013 02/09/2013 16/08/2013	Details
Resin acids and Rosin acids, fumarated, esters with pentaerythritol	305-514-1	94581-15-4	Reproductive toxicity (pre-natal developmental toxicity)	16/07/2012	30/08/2012	Details
Sodium N-(2-carboxyethyl)-N-(2-ethylhexyl)-β-alaninate	305-318-6	94441-92-6	Reproductive toxicity (pre-natal developmental toxicity)	02/06/2014	17/07/2014	Details
Saccharomyces cerevisiae, lysate	305-230-8	94350-12-6	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	30/09/2021 30/09/2021	15/11/2021 15/11/2021	Details
Trimethyl-3-[(1-oxo-10-undecenyl)amino]propylammonium methyl sulphate	304-990-8	94313-91-4	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Methyl trimethyl-3-[(1-oxododecyl)amino]propylammonium sulphate EC 234-204-8 \|\| Note: Testing proposal is based on concern identified by the registrant	16/12/2020	01/02/2021	Details
Aluminum, benzoate C16-18-fatty acids complexes	303-385-6	94166-87-7	Reproductive toxicity (pre-natal developmental toxicity)	25/06/2015	10/08/2015	Details
Boric acid (H3BO3), reaction products with ethanolamine	302-207-4	-	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	16/01/2012 16/01/2012 16/01/2012	01/03/2012 01/03/2012 01/03/2012	Details
(octahydro-4,7-methano-1H-indenyl)methyl acrylate	300-723-4	93962-84-6	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant.	23/11/2020	07/01/2021	Details
3-[[3-[[(2-cyanoethyl)amino]methyl]-3,5,5-trimethylcyclohexyl]amino]propiononitrile	300-496-1	93940-97-7	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	27/01/2020 27/01/2020	12/03/2020 12/03/2020	Details
Silicic acid (H4SiO4), tetraethyl ester, reaction products with bis(acetyloxy)dibutylstannane	300-344-4	93925-42-9	Genetic toxicity in vivo	21/01/2021	08/03/2021	Details
Gas oils, paraffinic	300-227-8	93924-33-5	Reproductive toxicity (two-generation reproductive toxicity)	02/09/2011	17/10/2011	Details
Alkenes, C24-28 α-	300-203-7	93924-11-9	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	31/05/2011 31/05/2011 25/06/2012	15/07/2011 15/07/2011 09/08/2012	Details
Alkenes, C20-24 α-	300-202-1	93924-10-8	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	31/05/2011 31/05/2011 25/06/2012	15/07/2011 15/07/2011 09/08/2012	Details
Reaction mass of (E)-3-methyl-5-phenylpent-2-enenitrile and (Z)-3-methyl-5-phenylpent-2-enenitrile	299-682-2	93893-89-1	Reproductive toxicity (pre-natal developmental toxicity)	16/12/2020	01/02/2021	Details
tripotassium propylsilanetriolate	299-135-8	93857-00-2	Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with [trimethoxypropylsilane] (EC 213-926-7) Sub-chronic toxicity (90 day): inhalation Note: testing proposed with [trimethoxypropylsilane] (EC 213-926-7)	16/03/2015 16/03/2015	30/04/2015 30/04/2015	Details
Zinc bis[O-(6-methylheptyl)] bis[O-(sec-butyl)] bis(dithiophosphate)	298-577-9	93819-94-4	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category" Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category" Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category"	04/10/2018 04/10/2018 04/10/2018	19/11/2018 19/11/2018 19/11/2018	Details
Alkenes, C15-18	297-797-2	93762-80-2	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	16/08/2011 16/08/2011 25/06/2012	30/09/2011 30/09/2011 09/08/2012	Details
Phosphorous acid, tri-C12-14-alkyl esters	297-701-9	93686-48-7	Bioaccumulation aquatic / sediment Reproductive toxicity (pre-natal developmental toxicity)	16/02/2015 16/02/2015	02/04/2015 02/04/2015	Details
Hydrocarbons, C4, 1,3-butadiene-free, polymd., triisobutylene fraction, hydrogenated	297-629-8	93685-81-5	Reproductive toxicity (two-generation reproductive toxicity)	25/06/2012	09/08/2012	Details
Hydrocarbons, C4, 1,3-butadiene-free, polymd., tetraisobutylene fraction, hydrogenated	297-628-2	-	Reproductive toxicity (two-generation reproductive toxicity)	25/06/2012	09/08/2012	Details
Ashes (residues), plant	297-049-5	93333-79-0	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	16/05/2011 16/05/2011 16/05/2011	30/06/2011 30/06/2011 30/06/2011	Details
Ashes (residues), plant	297-049-5	93333-79-0	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	31/01/2018 31/01/2018	19/03/2018 19/03/2018	Details
2-Naphthalenol, 1-[[4-(phenylazo)phenyl]azo]-, ar-heptyl ar',ar''-Me derivs.	296-120-8	92257-31-3	Genetic toxicity in vivo	16/12/2020	01/02/2021	Details
Rosin, fumarated, reaction products with glycerol and pentaerythritol	296-047-1	92202-14-7	Reproductive toxicity (pre-natal developmental toxicity) //Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7) Reproductive toxicity (two-generation reproductive toxicity) //Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with pentaerythritol (CAS RN 94581-15-4) Reproductive toxicity (two-generation reproductive toxicity) \|\| Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with pentaerythritol (CAS 94581-15-4) Sub-chronic toxicity (90-day): oral //Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7), Resin acids and Rosin acids, fumarated, esters with pentaerythritol (CAS RN 94581-15-4), and Rosin acids and resin acids, maleated, esters with pentaerythritol (CAS RN 94581-17-6) Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS 97489-11-7); Resin acids and Rosin acids, fumarated, esters with pentaerythritol (CAS 94581-15-4); and Rosin acids and resin acids, maleated, esters with pentaerythritol (CAS 94581-17-6)	19/07/2013 19/07/2013 02/07/2013 19/07/2013 02/07/2013	02/09/2013 02/09/2013 16/08/2013 02/09/2013 16/08/2013	Details
Rosin, fumarated, reaction products with glycerol and pentaerythritol	296-047-1	92202-14-7	Reproductive toxicity (pre-natal developmental toxicity)	16/07/2012	30/08/2012	Details
Resin acids and Rosin acids, reaction products with formaldehyde, potassium salt	295-855-1	92129-53-8	Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin (CAS RN 8050-09-7), Rosin, hydrogenated (CAS RN 65997-06-0), and Rosin, reaction products with formaldehyde (CAS RN 91081-53-7)	02/07/2013	16/08/2013	Details
Fatty acids, tall-oil, compds. with N-[3-(dimethylamino)propyl]tall-oil amides	295-714-4	92128-22-8	Long-term toxicity to fish	03/10/2023	17/11/2023	Details
Fatty acids, tall-oil, compds. with N-[3-(dimethylamino)propyl]tall-oil amides	295-714-4	92128-22-8	Reproductive toxicity (pre-natal developmental toxicity)	28/02/2018	16/04/2018	Details
dihydro-3-(tripropenyl)furan-2,5-dione	295-556-6	92077-08-2	Reproductive toxicity (pre-natal developmental toxicity)	30/09/2015	16/11/2015	Details
Residues (petroleum), thermal cracked vacuum	295-518-9	92062-05-0	Genetic toxicity in vivo\|\|Note: testing proposed with Asphalt (EC no. 232-490-9) Reproductive toxicity (extended one-generation reproductive toxicity study)\|\|Note: testing proposed with Asphalt (EC no. 232-490-9) Reproductive toxicity (pre-natal developmental toxicity)\|\|Note: testing proposed with Asphalt (EC no. 232-490-9) Sub-chronic toxicity (90-day): oral\|\|Note: testing proposed with Asphalt (EC no. 232-490-9)	04/12/2023 04/12/2023 04/12/2023 04/12/2023	18/01/2024 18/01/2024 18/01/2024 18/01/2024	Details
Residues (petroleum), thermal cracked vacuum	295-518-9	92062-05-0	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity)	16/08/2011 16/08/2011	30/09/2011 30/09/2011	Details
Residues (petroleum), thermal cracked vacuum	295-518-9	062-05-0	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with Asphalt (CAS 8052-42-4)	25/06/2019	09/08/2019	Details
Gas oils (petroleum), hydrotreated light vacuum	295-407-5	92045-24-4	Reproductive toxicity (two-generation reproductive toxicity)	15/07/2011	29/08/2011	Details
Hydrocarbons, C4, steam-cracker distillate	295-405-4	92045-23-3	Reproductive toxicity (extended one-generation reproductive toxicity study)\|\|Note: testing proposed with Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC no. 306-004-1) Reproductive toxicity (pre-natal developmental toxicity)\|\|Note: testing proposed with Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC no. 306-004-1) Sub-chronic toxicity (90 day): inhalation\|\|Note: testing proposed with Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC no. 306-004-1)	06/06/2023 06/06/2023 06/06/2023	21/07/2023 21/07/2023 21/07/2023	Details
Extracts (petroleum), deasphalted vacuum residue solvent	295-332-8	91995-70-9	Reproductive toxicity (two-generation reproductive toxicity)	29/07/2011	12/09/2011	Details
Extracts (petroleum), deasphalted vacuum residue solvent	295-332-8	91995-70-9	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): dermal	28/02/2019 28/02/2019 28/02/2019	15/04/2019 15/04/2019 15/04/2019	Details
Extracts (petroleum), deasphalted vacuum residue solvent	295-332-8	91995-70-9	Reproductive toxicity (extended one-generation reproductive toxicity study)\|\|Note: testing proposed with Extracts (petroleum), residual oil solvent (EC no. 265-110-5)	06/06/2023	21/07/2023	Details
Cobalt, borate propionate complexes	295-033-2	91782-61-5	Carcinogenicity \|\| Note: testing proposed with Cobalt dichloride (EC 231-589-4) \|\| Note: Testing proposal is based on concern identified by the registrant. Genetic toxicity in vivo \|\| Note: testing proposed with Cobalt sulphate (EC 233-334-2) \|\| Note: Testing proposal is based on concern identified by the registrant.	21/09/2020 21/09/2020	05/11/2020 05/11/2020	Details
Cobalt, borate 2-ethylhexanoate complexes	295-032-7	91782-60-4	Carcinogenicity \|\| Note: testing proposed with Cobalt dichloride (EC 231-589-4) \|\| Note: Testing proposal is based on concern identified by the registrant Genetic toxicity in vivo \|\| Note: testing proposed with Cobalt sulphate (EC 233-334-2) \|\| Note: Testing proposal is based on concern identified by the registrant	07/07/2020 07/07/2020	21/08/2020 21/08/2020	Details
Tar, wood	294-436-0	91722-33-7	Reproductive toxicity (pre-natal developmental toxicity)	23/02/2022	12/04/2022	Details
Resin acids and Rosin acids, maleated, calcium salts	294-402-5	91722-01-9	Reproductive toxicity (pre-natal developmental toxicity) //Note: to be tested with Rosin, maleated (CAS RN 8050-28-0) Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin, fumarated (CAS RN 65997-04-7) and Rosin, maleated (CAS RN 8050-28-0)	02/07/2013 02/07/2013	16/08/2013 16/08/2013	Details
1,3-Propanediol, 2,2-bis(hydroxymethyl)-, allyl ether	293-883-9	91648-24-7	Bioaccumulation aquatic / sediment \|\| Note: Testing proposal is based on concern identified by the registrant.	23/11/2020	07/01/2021	Details
1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-C12-14 acyl derivs., hydroxides, inner salts	293-878-1	91648-19-0	Long-term toxicity to fish \|\| Note: testing proposed with 1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C12-18(even numbered) acyl) derivs., hydroxides, inner salts (EC 939-457-4) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with 1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C8-18(even numbered) acyl) derivs., hydroxides, inner salts (EC 939-455-3) Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with 1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C8-18(even numbered) acyl) derivs., hydroxides, inner salts (EC 939-455-3)	18/06/2018 18/06/2018 18/06/2018	02/08/2018 02/08/2018 02/08/2018	Details
Rosin, reaction products with formaldehyde	293-659-0	91081-53-7	Reproductive toxicity (pre-natal developmental toxicity)	06/03/2012	20/04/2012	Details
Rosin, reaction products with formaldehyde	293-659-0	91081-53-7	Reproductive toxicity (pre-natal developmental toxicity) //Note: testing proposed with Rosin (CAS RN 8050-09-7) Reproductive toxicity (two-generation reproductive toxicity) \|\| Note: testing proposed with _ Rosin (CAS RN 8050-09-7) Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with Rosin (CAS RN 8050-09-7), Rosin, hydrogenated (CAS RN 65997-06-0), Rosin, reaction products with formaldehyde (CAS RN 91081-53-7)	19/07/2013 02/07/2013 02/07/2013	02/09/2013 16/08/2013 16/08/2013	Details
Hydrocarbons, C4, 1,3-butadiene-free, polymd., triisobutylene fraction	293-263-8	91053-01-9	Reproductive toxicity (extended one-generation reproductive toxicity study)\|\|Note: testing proposed with Butene, homopolymer (products derived from either/or But-1-ene/But-2-ene) (EC no. 500-004-7) Reproductive toxicity (pre-natal developmental toxicity)\|\|Note: testing proposed with Butene, homopolymer (products derived from either/or But-1-ene/But-2-ene) (EC no. 500-004-7) Sub-chronic toxicity (90-day): oral\|\|Note: testing proposed with Butene, homopolymer (products derived from either/or But-1-ene/But-2-ene) (EC no. 500-004-7)	06/06/2023 06/06/2023 06/06/2023	21/07/2023 21/07/2023 21/07/2023	Details
Fatty acids, C16-18, reaction products with diethanolamine	293-014-3	91032-08-5	Reproductive toxicity (pre-natal developmental toxicity)	16/03/2015	30/04/2015	Details
Fatty acids, C16-18, isononyl esters	292-960-4	91031-57-1	Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	30/06/2023 30/06/2023 30/06/2023	14/08/2023 14/08/2023 14/08/2023	Details
Fatty acids, C16-18, barium salts	292-883-6	91002-07-2	Long-term toxicity to fish //Note: testing to be done with barium dichloride (CAS number 10361-37-2)	04/04/2014	19/05/2014	Details
Amines, polyethylenepoly-, triethylenetetramine fraction	292-588-2	90640-66-7	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	22/11/2017 22/11/2017	08/01/2018 08/01/2018	Details
Amines, polyethylenepoly-, triethylenetetramine fraction,Triethylenetetramine linear, cyclic and branched	292-588-2	90640-66-7	Reproductive toxicity (two-generation reproductive toxicity)	05/04/2011	20/05/2011	Details
Amines, polyethylenepoly-, triethylenetetramine fraction,Triethylenetetramine linear, cyclic and branched	292-588-2	90640-66-7	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	01/09/2017 01/09/2017	16/10/2017 16/10/2017	Details
Amines, polyethylenepoly-, tetraethylenepentamine fraction	292-587-7	90640-66-7	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with TETA (CAS 90640-67-8) and HEPA (68121-73-7) Reproductive toxicity (pre-natal developmental toxicity )	31/01/2018 31/01/2018	19/03/2018 19/03/2018	Details
Amines, polyethylenepoly-, tetraethylenepentamine fraction	292-587-7	90640-66-7	Reproductive toxicity (extended one-generation reproductive toxicity study)	01/11/2015	16/12/2015	Details
Alkanes, C12-26-branched and linear	292-454-3	90622-53-0	Reproductive toxicity (two-generation reproductive toxicity)	15/09/2011	31/10/2011	Details
Alkenes, C13-14, hydroformylation products, distn. residues	292-429-7	90622-29-0	Reproductive toxicity (extended one-generation reproductive toxicity study) “\|\| Note: testing proposed with Alkenes, C11-12, hydroformylation products, distn. residues (EC 292-427-6)	02/11/2018	17/12/2018	Details
Alkenes, C13-14, hydroformylation products, distn. Residues	292-429-7	90622-29-0	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	15/09/2011 15/09/2011 15/09/2011	31/10/2011 31/10/2011 31/10/2011	Details
Alkenes, C11-12, hydroformylation products, distn. Residues	292-427-6	90622-27-8	Reproductive toxicity (extended one-generation reproductive toxicity study)	28/02/2018	16/04/2018	Details
Alkenes, C11-12, hydroformylation products, distn. residues	292-427-6	90622-27-8	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	15/09/2011 15/09/2011 15/09/2011	31/10/2011 31/10/2011 31/10/2011	Details
1,5-Pentanediamine, 2-methyl-, reaction products with 2-ethyl-1,4-butanediamine and glycidyl tolyl ether	291-813-1	90480-76-5	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	19/10/2020 19/10/2020	03/12/2020 03/12/2020	Details
Hydrochloric acid, reaction products with aniline and nitrobenzene, sulfonated, sodium salts	291-454-0	90411-76-0	Reproductive toxicity (pre-natal developmental toxicity)	30/11/2015	14/01/2016	Details
1,2,4-Benzenetricarboxylic acid, mixed decyl and octyl triesters	290-754-9	90218-76-1	Sub-chronic toxicity (90-day): oral	29/07/2011	12/09/2011	Details
Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Bu and iso-Pr) esters, zinc salts	288-917-4	85940-28-9	"Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) ""Testing proposed according to a plan for the ZDDP category.“ " Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category" Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“	04/10/2018 04/10/2018 04/10/2018	19/11/2018 19/11/2018 19/11/2018	Details
Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Bu and iso-Pr) esters, zinc salts	288-917-4	85940-28-9	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with a read-across member of the ZDDP category Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), and Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1) Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1)	21/12/2021 21/12/2021 21/12/2021	04/02/2022 04/02/2022 04/02/2022	Details
Fatty acids, tall-oil, compds. with oleylamine	288-315-1	85711-55-3	Long-term toxicity to fish	04/04/2014	19/05/2014	Details
Alkenes, C10-14	288-213-7	85681-75-0	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	15/09/2011 15/09/2011 25/06/2012	31/10/2011 31/10/2011 09/08/2012	Details
Alcohols, C13-15-branched and linear	287-625-4	85566-16-1	Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study)	31/01/2023 31/01/2023	17/03/2023 17/03/2023	Details
Alcohols, C13-15-branched and linear	287-625-4	85566-16-1	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with Isotridecan-1-ol (EC 248-469-2)	16/12/2020	01/02/2021	Details
Alkenes, C10-13	287-479-1	85535-87-1	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity)	15/09/2011 15/09/2011	31/10/2011 31/10/2011	Details
Alkanes, C10-13, chloro (Short Chain Chlorinated Paraffins)	287-476-5	85535-84-8	Reproductive toxicity (two-generation reproductive toxicity)	29/07/2011	12/09/2011	Details
2,4,8,10-tetra(tert-butyl)-6-hydroxy-12H-dibenzo[d,g][1,3,2]dioxaphosphocin 6-oxide, sodium salt	286-344-4	85209-91-2	Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity)	16/10/2014 16/10/2014 16/10/2014	01/12/2014 01/12/2014 01/12/2014	Details
2-Butenedioic acid (Z)-, ester with 1,2-propanediol, compd. with 2-(dibutylamino)ethanol	286-304-6	85204-10-0	Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	02/06/2014 02/06/2014 02/06/2014 02/06/2014	17/07/2014 17/07/2014 17/07/2014 17/07/2014	Details
Disodium 6-amino-5-[[4-[(2-bromo-1-oxoallyl)amino]-2-[(4-methyl-3-sulphonatophenyl)sulphonyl]phenyl]azo]naphthalene-2-sulphonate	286-122-7	85187-33-3	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant	18/02/2021	05/04/2021	Details
2-ethylhexanoic acid, monoester with propane-1,2-diol	285-503-5	85114-00-7	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	03/03/2014 03/03/2014	17/04/2014 17/04/2014	Details
Fatty acids, C16-18 and C18-unsatd., Et esters	285-206-0	85049-36-1	Long-term toxicity to fish	01/07/2011	15/08/2011	Details
Phosphoric acid, mixed esters with Bu alc. and ethylene glycol	284-716-0	84962-20-9	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Phosphoric acid, butyl ester; CAS No. 12788-93-1 Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with Phosphoric acid, butyl ester; CAS No. 12788-93-1	20/05/2015 20/05/2015	06/07/2015 06/07/2015	Details
1,1'-(ethane-1,2-diyl)bis[pentabromobenzene]	284-366-9	84852-53-9	Reproductive toxicity (extended one-generation reproductive toxicity study)	24/02/2020	09/04/2020	Details
Star anise, Illicium verum, ext.	283-518-1	84650-59-9	Genetic toxicity in vivo	22/04/2021	07/06/2021	Details
Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts	283-392-8	84605-29-8	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) and another read-across member from ZDDP category Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with the substance, with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0), Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5) and Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1) Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed the substance, with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0), Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6) and Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5)	21/12/2021 21/12/2021 21/12/2021	04/02/2022 04/02/2022 04/02/2022	Details
Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts	283-392-8	84605-29-8	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing Proposed according to a plan for the ZDDP category" Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“ Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing Proposed according to a plan for the ZDDP category"	04/10/2018 04/10/2018 04/10/2018	19/11/2018 19/11/2018 19/11/2018	Details
2-Butenoic acid, 4-oxo-4-(tridecylamino)-, (Z)-, branched	283-219-6	84583-68-6	Sub-chronic toxicity (90-day): oral	12/04/2017	29/05/2017	Details
Ethyl phenyl(2,4,6-trimethylbenzoyl)phosphinate	282-810-6	84434-11-7	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/05/2014 16/05/2014	30/06/2014 30/06/2014	Details
1,3-Benzenediamine, coupled with diazotized m-phenylenediamine, acetates	282-617-7	84281-74-3	Genetic toxicity in vivo	25/11/2021	10/01/2022	Details
1,2-Ethanediamine, N-(2-aminoethyl)-, reaction products with glycidyl tolyl ether	282-199-6	84144-79-6	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: Testing proposal is based on concern identified by the registrant.	18/03/2021	03/05/2021	Details
4-(1,1-dimethylethyl)cyclohexyl acrylate	282-104-8	84100-23-2	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	23/03/2020 23/03/2020	07/05/2020 07/05/2020	Details
Formaldehyde, reaction products with ethylenediamine	281-928-5	84066-92-2	Genetic toxicity in vivo	16/05/2014	30/06/2014	Details
Benzoic acid, 2-hydroxy-, mono-C>13-alkyl derivs., calcium salts (2:1)	281-018-8	83846-43-9	Sub-chronic toxicity (90-day): oral	18/06/2018	02/08/2018	Details
Bis(2,4,4-trimethylpentyl)phosphinic acid	280-445-7	83411-71-6	Sub-chronic toxicity (90-day): oral	18/03/2021	03/05/2021	Details
Bis(2,4,4-trimethylpentyl)phosphinic acid	280-445-7	83411-71-6	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	29/04/2014 29/04/2014	13/06/2014 13/06/2014	Details
Bis(trimethoxysilylpropyl)amine	280-084-5	82985-35-1	Reproductive toxicity (pre-natal developmental toxicity Sub-chronic toxicity (90-day): oral	17/06/2020 17/06/2020	03/08/2020 03/08/2020	Details
Amines, C11-14-branched alkyl, monohexyl and dihexyl phosphates	279-632-6	80939-62-4	Sub-chronic toxicity (90-day): oral	23/11/2020	07/01/2021	Details
Sodium 1-amino-4-[[3,5-bis[[(chloroacetyl)amino]methyl]-2,4,6-trimethylphenyl]amino]-9,10-dihydro-9,10-dioxoanthracene-2-sulphonate	279-365-5	80010-51-1	Genetic toxicity in vivo	18/03/2021	03/05/2021	Details
Trisodium 4-amino-5-hydroxy-3-[[4-[[2-oxo-1-[(phenylamino)carbonyl]propyl]azo]phenyl]azo]-6-[(4-sulphonato-1-naphthyl)azo]naphthalene-2,7-disulphonate	279-093-7	79135-92-5	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant.	21/01/2021	08/03/2021	Details
Sulfonium compounds, C11-14-alkylbis(hydroxyethyl), 2-hydroxyethyl sulfates (salts)	278-855-6	78169-20-7	Reproductive toxicity (pre-natal developmental toxicity)	18/02/2014	04/04/2014	Details
N,N-dimethyl-N'-(2,2,6,6-tetramethylpiperidin-4-yl)propane-1,3-diamine	278-817-9	78014-16-1	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	26/08/2021 26/08/2021 26/08/2021	11/10/2021 11/10/2021 11/10/2021	Details
Triisotridecyl phosphite	278-758-9	77745-66-5	Sub-chronic toxicity (90-day): oral	25/06/2019	09/08/2019	Details
Diphenyl(2,4,6-trimethylbenzoyl)phosphine oxide	278-355-8	75980-60-8	Reproductive toxicity (pre-natal developmental toxicity)	18/02/2014	04/04/2014	Details
Disodium oxybis[methylbenzenesulphonate]	277-242-0	73037-34-0	Reproductive toxicity (pre-natal developmental toxicity)	17/06/2014	01/08/2014	Details
7,7,9(or 7,9,9)-trimethyl-4,13-dioxo-3,14-dioxa-5,12-diazahexadecane-1,16-diyl bismethacrylate	276-957-5	72869-86-4	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant	19/10/2020	03/12/2020	Details
5,5'-dithiodi-1,3,4-thiadiazole-2(3H)-thione	276-763-0	72676-55-2	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/12/2020 16/12/2020	01/02/2021 01/02/2021	Details
5,5'-dithiodi-1,3,4-thiadiazole-2(3H)-thione	276-763-0	72676-55-2	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant	20/10/2016	05/12/2016	Details
5,5'-dithiodi-1,3,4-thiadiazole-2(3H)-thione	276-763-0	72676-55-2	Long-term toxicity to fish	30/06/2023	14/08/2023	Details
Iron, complexes with diazotized 5-amino-2-(phenylamino)benzenesulfonic acid monosodium salt coupled with 4-[(2-hydroxy-3,5-dinitrophenyl)azo]-1,3-benzenediol, diazotized 4-nitrobenzenamine and diazotized 3-aminobenzenesulfonic acid monosodium salt	276-464-5	72207-77-3	Genetic toxicity in vivo \|\| Note: testing proposed with Acid Brown 360 (EC 946-788-8)	20/05/2021	05/07/2021	Details
4,6-dichloro-N-(1,1,3,3-tetramethylbutyl)-1,3,5-triazin-2-amine	276-309-1	72058-41-4	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity)	23/11/2020 23/11/2020	07/01/2021 07/01/2021	Details
6-[(1-oxomethyloctyl)amino]hexanoic acid	276-173-3	71902-23-3	Reproductive toxicity (pre-natal developmental toxicity)	10/03/2017	25/04/2017	Details
Quaternary ammonium compounds, C12-18-alkylbis(hydroxyethyl)methyl, chlorides	276-038-9	71808-53-2	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	15/07/2014 15/07/2014	29/08/2014 29/08/2014	Details
Ethanol, 2,2'-iminobis-, N-C12-18-alkyl derivs.	276-014-8	71786-60-2	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90 day): oral	14/08/2014 14/08/2014 14/08/2014	28/09/2014 28/09/2014 28/09/2014	Details
Ethanol, 2,2'-iminobis-, N-C12-18-alkyl derivs.	276-014-8	71786-60-2	Reproductive toxicity (extended one-generation reproductive toxicity study)	25/06/2019	09/08/2019	Details
m-(2,3-epoxypropoxy)-N,N-bis(2,3-epoxypropyl)aniline	275-662-9	71604-74-5	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	15/07/2014 15/07/2014 15/07/2014 15/07/2014	29/08/2014 29/08/2014 29/08/2014 29/08/2014	Details
[1α(E),2β]-1-(2,6,6-trimethylcyclohex-3-en-1-yl)but-2-en-1-one	275-156-8	71048-82-3	Reproductive toxicity (pre-natal developmental toxicity)	26/10/2022	12/12/2022	Details
Octasodium 2,2'-[1,4-phenylenebis[imino(6-chloro-1,3,5-triazine-4,2-diyl)imino(1-hydroxy-3,6-disulphonatonaphthalene-2,8-diyl)azo]]bisnaphthalene-1,5-disulphonate	275-108-6	71002-20-5	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: Testing proposal is based on concern identified by the registrant	16/12/2020	01/02/2021	Details
Phenol, 2-methoxy-, reaction products with 2,2-dimethyl-3-methylenebicyclo[2.2.1]heptane, hydrogenated	275-062-7	70955-71-4	Reproductive toxicity (extended one-generation reproductive toxicity study)	26/08/2021	11/10/2021	Details
Formaldehyde, reaction products with m-phenylenediamine, sodium sulfide (Na2S) and sulfur	274-986-8	70892-34-1	Genetic toxicity in vivo	15/01/2024	29/02/2024	Details
O-(2-ethylhexyl) O,O-tert-pentyl peroxycarbonate	274-919-2	70833-40-8	Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	03/10/2023 03/10/2023 03/10/2023	17/11/2023 17/11/2023 17/11/2023	Details
O-(2-ethylhexyl) O,O-tert-pentyl peroxycarbonate	274-919-2	70833-40-8	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	03/03/2014 03/03/2014	17/04/2014 17/04/2014	Details
[[(phosphonomethyl)imino]bis[ethylenenitrilobis(methylene)]]tetrakisphosphonic acid, ammonium salt	274-798-6	70714-66-8	Reproductive toxicity (extended one-generation reproductive toxicity study)\|\|Note: testing proposed with Sodium salts of [[(phosphonomethyl)imino]bis[ethane-2,1-diylnitrilobis(methylene)]]tetrakisphosphonic acid (5-7 Na:1) (EC no. 701-216-4)	01/03/2023	17/04/2023	Details
3-(benzothiazol-2-yl)-7-(diethylamino)-2-oxo-2H-1-benzopyran-4-carbonitrile	274-668-9	70546-25-7	Genetic toxicity in vivo	19/10/2020	03/12/2020	Details
2-(2H-benzotriazol-2-yl)-4,6-bis(1-methyl-1-phenylethyl)phenol	274-570-6	70321-86-7	Bioaccumulation aquatic / sediment	15/07/2014	29/08/2014	Details
Disodium 4-[4-[[5-[(2-bromo-1-oxoallyl)amino]-2-sulphonatophenyl]azo]-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl]-2,5-dichlorobenzenesulphonate	274-499-0	70247-70-0	Genetic toxicity in vivo	18/02/2021	05/04/2021	Details
Disodium [2,4-dihydro-4-[(2-hydroxy-5-nitrophenyl)azo]-5-methyl-2-phenyl-3H-pyrazol-3-onato(2-)][3-hydroxy-4-[(2-hydroxy-1-naphthyl)azo]-7-nitronaphthalene-1-sulphonato(3-)]chromate(2-)	274-490-1	70236-60-1	Genetic toxicity in vivo	21/10/2021	07/12/2021	Details
Disodium 6-amino-5-[[4-[(2-bromo-1-oxoallyl)amino]-2-sulphonatophenyl]azo]-4-hydroxynaphthalene-2-sulphonate	274-437-2	70210-40-1	Genetic toxicity in vivo	18/02/2021	05/04/2021	Details
Disodium 5-[[4-[(2-bromo-1-oxoallyl)amino]-2-sulphonatophenyl]azo]-4-hydroxy-6-(methylamino)naphthalene-2-sulphonate	274-436-7	70210-39-8	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant	19/10/2020	03/12/2020	Details
Disodium 1-amino-4-[[4-[(2-bromo-1-oxoallyl)amino]-2-sulphonatophenyl]amino]-9,10-dihydro-9,10-dioxoanthracene-2-sulphonate	274-397-6	70209-99-3	Genetic toxicity in vivo	18/03/2021	03/05/2021	Details
Slags, silicomanganese-manufg.	273-733-9	69012-33-5	Reproductive toxicity (pre-natal developmental toxicity)\|\| Note: testing proposed with Slags, ferromanganese-manufg. CAS No 69012-28-8 (EC No 273-728-1)	25/10/2017	11/12/2017	Details
Slags, phosphorus-manufg.	273-732-3	69012-32-4	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90 day): inhalation	01/07/2011 01/07/2011 01/07/2011	15/08/2011 15/08/2011 15/08/2011	Details
Slags, ferromanganese-manufg.	273-728-1	69012-28-8	Reproductive toxicity (pre-natal developmental toxicity)	26/03/2018	11/05/2018	Details
Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Bu and pentyl) esters, zinc salts	273-527-9	68988-45-4	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category" Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category"	04/10/2018 04/10/2018	19/11/2018 19/11/2018	Details
Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Bu and pentyl) esters, zinc salts	273-527-9	68988-45-4	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with a read-across member of the ZDDP category(identity of test material not yet decided) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), and Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6) Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), and Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6)	21/12/2021 21/12/2021 21/12/2021	04/02/2022 04/02/2022 04/02/2022	Details
Resin acids and Rosin acids, cobalt salts	273-321-9	68956-82-1	Reproductive toxicity (pre-natal developmental toxicity)\|\|Note: testing proposed with Neodecanoic acid, cobalt salt (EC no. 248-373-0)	28/11/2022	12/01/2023	Details
Resin acids and Rosin acids, cobalt salts	273-321-9	68956-82-1	Genetic toxicity in vivo \|\| Note: testing proposed with Cobalt sulphate (EC 233-334-2)	21/01/2021	08/03/2021	Details
Octene, hydroformylation products, low-boiling	273-110-1	68938-03-4	Genetic toxicity in vivo	17/06/2014	01/08/2014	Details
Octene, hydroformylation products, low-boiling	273-110-1	68938-03-4	Reproductive toxicity (pre-natal developmental toxicity)	23/11/2020	07/01/2021	Details
Polysulfides, di-tert-Bu	273-103-3	68937-96-2	Bioaccumulation aquatic / sediment	01/07/2011	15/08/2011	Details
Phenol, isopropylated, phosphate (3:1)	273-066-3	68937-41-7	Reproductive toxicity (pre-natal developmental toxicity)	30/06/2023	14/08/2023	Details
Phenol, isopropylated, phosphate (3:1)	273-066-3	68937-41-7	Reproductive toxicity (extended one-generation reproductive toxicity study)	26/03/2018	11/05/2018	Details
Phenol, isopropylated, phosphate (3:1)	273-066-3	68937-41-7	Bioaccumulation aquatic / sediment Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	29/07/2011 29/07/2011 29/07/2011 29/07/2011 29/07/2011	12/09/2011 12/09/2011 12/09/2011 12/09/2011 12/09/2011	Details
Benzenamine, N-phenyl-, reaction products with styrene and 2,4,4-trimethylpentene	272-940-1	68921-45-9	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with the smallest aryl- and alkyl-substituted materials Reproductive toxicity (two-generation reproductive toxicity) \|\| Note: testing proposed with the smallest aryl- and alkyl-substituted materials	14/08/2014 14/08/2014	28/09/2014 28/09/2014	Details
Fatty acids, tall-oil, reaction products with 2-[(2-aminoethyl)amino]ethanol	272-902-4	68919-76-6	Reproductive toxicity (pre-natal developmental toxicity)	10/03/2017	25/04/2017	Details
Fatty acids, tall-oil, reaction products with 2-[(2-aminoethyl)amino]ethanol	272-902-4	68919-76-6	Sub-chronic toxicity (90 day): oral	16/05/2014	30/06/2014	Details
Gas oils (petroleum), straight-run, high-boiling	272-818-8	68915-97-9	Reproductive toxicity (two-generation reproductive toxicity)	02/09/2011	17/10/2011	Details
Distillates (petroleum), heavy straight-run	272-817-2	68915-96-8	Reproductive toxicity (two-generation reproductive toxicity)	02/09/2011	17/10/2011	Details

2 011 eredményből 601 - 800 megmutatása.

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