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EC number: 828-479-9 | CAS number: 2088841-41-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The acute toxic effects of the structurally related UVCB EDDHMA-Fe to Daphnia magna were investigated according to the principles of OECD-Guideline 202 and EU method C.2. The EC50 for a 48 hour exposure was 4.6 g/L based on the study with EDDHMA-Fe which provides a true EC50 value (Thun, 1990).
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 4.6 g/L
Additional information
- Key study by Thun, 1990 with EDDHMA-Fe :
Concentrations tested were 1.0, 1.4, 1.9, 2.6, 3.6, 5.1, 7.1 and 10 g/L EDDHMA-FeK based on a preliminary test. The 48 hour EC50 was determined at 4.6 g/L test substance, with 95% confidence intervals between 4.12 and 6.0 g/L. Due to strong coloration by the test substance only a 48h assessment was done.
Since this study provides a true EC50 and is of equal or highest reliability, it is preferred over the other studies to be considered key.
- Supporting study by Bogers, 1992 with EDDHMA-Fe :
Under the conditions of the study EDDHMA-FeNa did not induce significant acute immobilization of Daphnia magna at or below 1000 mg/L after 48 hours of exposure. Hence, the 48h-EC50 was greater than 1000 mg/L, being the No Observed Effect Level (NOEC) for mobility of Daphnia magna.
- Supporting study by BASF, 2010 with EDDHA-Fe:
In the study the acute toxic effects of EDDHA-FeNa to Daphnia magna were determined according to the principles of OECD-Guideline 202 and EU method C.2. A limit test with a nominal concentration of 120 mg/L was carried out at a static system. The EC50 for a 48 hour exposure was greater than 120 mg/L based on the nominal concentration of the test substance and greater than 122 mg/L based on the mean measured concentrations.
- Additionally, a study investigating the acute toxicity of EDDHMA-Na4 is given (Engstrom, 1986) as supporting evidence that these similar chelate structures have no high acute toxicity to daphnids. In this study the EC50 (96h) proved > 1200, but < 2400 mg/L the highest concentration tested at which 100% mortality was observed. No clear EC50 could be determined.
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