Registration Dossier
Registration Dossier
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EC number: 700-161-3 | CAS number: -
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Read-across from the Zonyl ELS study indicates the following results: 90-day NOEC and LOEC were 2.5 mg/L and 5 mg/L based on nominal Zonyl concentrations (0.88 mg/L and 1.75 mg/L based on nominal 35% a.i. in Zonyl)
Key value for chemical safety assessment
Additional information
Zonyl and TNS are considered sufficiently similar to facilitate a read-across of this data endpoint. In this case, experimental data in accordance with test guidelines OPPTS 850.1400; OECD 210; a flow-through study with Zonyl using measured test concentrations and conducted under GLP is available. This study gave rise to the following results: 90-day NOEC and LOEC were 2.5 mg/L and 5 mg/L based on nominal Zonyl concentrations (0.88 mg/L and 1.75 mg/L based on nominal 35% solids in Zonyl). Mean measured concentrations of Zonyl were within 80% of nominal concentrations, therefore, results are reported based on nominal Zonyl concentrations. As part of weight of evidence approach, the chronic study on the closely related Zonyl, adequately addresses the long-term effects in fish information requirement.
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