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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 619-997-4 | CAS number: 764667-65-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Administrative data
First-aid measures
Inhalation: If inhaled, remove to fresh air. If breathing is difficult, give oxygen. Get medical attention in case of prolonged exposure.
Ingestion: Do not induce vomiting unless directed to do so by medical personnel. Get medical attention if symptoms appear.
Skin contact: Wash with plenty of soap and water. Get medical attention if irritation occurs.
Eye contact: In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention if irritation occurs.
Protection of first-aiders: No action shall be taken involving any personal risk or without suitable training. Treat supportively and symptomatically.
Fire-fighting measures
Special hazards arising from the chemical: No specific data.
Special protective actions for fire-fighters: Promptly isolate the scene by removing all persons from the vicinity of the incident if there is a fire. No action shall be taken involving any personal risk or without suitable training. Additional information: Fire-fighters should wear appropriate protective equipment and self-contained breathing apparatus (SCBA) with a full face-piece operated in positive pressure mode.
Accidental release measures
Personal precautions, protective equipment and emergency procedures: Immediately contact emergency personnel. Keep unnecessary personnel away. Follow all firefighting procedures .
Environmental precautions: Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers. Inform the relevant authorities if the product has caused environmental pollution (sewers, waterways, soil or air).
Methods and material for containment and cleaning up: Move containers from spill area. Prevent entry into sewers, water courses, basements or confined areas. Vacuum or sweep up material and place in adesignated, labeled waste container. Dispose of via a licensed waste disposal contractor.
Handling and storage
The substance is an intermediate only used in a synthesis process to produce an Active Pharmaceutical Ingredient (A.P.I.).
See attached file in section 13 for Information on details of the risk management measures applied at the manufacturing/use site a in order to achieve strictly controlled conditions.
Precautions for safe handling: Put on appropriate personal protective equipment. Eating, drinking and smoking should be prohibited in areas where this material is handled, stored and processed. Workers should wash hands and face before eating, drinking and smoking.
Conditions for safe storage, including any incompatibilities: Store in accordance with local regulations. Store in original container protected from direct sunlight in a dry, cool and well-ventilated area, away from incompatible materials and food and drink. Keep container tightly closed and sealed until ready for use. Containers that have been opened must be carefully resealed and kept upright to prevent leakage. Do not store in unlabeled containers. Use appropriate containment to avoid environmental contamination.
Transport information
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Marine transport (UN RTDG/IMDG)
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Exposure controls / personal protection
Hygiene measures: Wash hands, forearms and face thoroughly after handling chemical products, before eating, smoking and using the lavatory and at the end of the working period. Appropriate techniques should be used to remove potentially contaminated clothing. Wash contaminated clothing before reusing. Ensure that eyewash stations and safety showers are close to the workstation location.
Respiratory protection: Use an appropriate approved air-purifying respirator equipped with HEPA cartridges/canisters where there is the potential for exceeding established occupational exposure limits or occupational exposure bands. When handling a compound in solution, a cartridge/canister appropriate for the solution may also be needed. Use redundant respiratory protection as a prudent practice for adjunct protection in addition to effective engineering controls. Use a positive pressure, air-supplied, pressure demand tight fitting respirator (e.g., SCBA or airline equipped with emergency escape bottle) where there is a potential for uncontrolled releases in excess of the respirator's capabilities,where exposure levels are unknown or where air-purifying respirators may not provide adequate protection.
Hand protection: Disposable chemical resistant gloves. Consider double gloving.
Eye protection: Safety glasses with side shields. Where the work environment or activity involves dusty conditions, mists or aerosols, wear the appropriate goggles. Wear a faceshield or other full face protection if there is a potential for direct contact to the face with dusts, mists, or aerosols.
Skin protection: Additional body garments should be used to avoid exposed skin surfaces (e.g. sleevelets, apron, disposable suit etc.), based on the task being performed. Use appropriate degowning techniques to remove potentially contaminated clothing
Stability and reactivity
Chemical stability: The product is stable.
Reactivity: Not available.
Possibility of hazardous reactions:Under normal conditions of storage and use, hazardous polymerization will not occur.
Hazardous decomposition products: Under normal conditions of storage and use, hazardous decomposition products should not be produced
Disposal considerations
Disposal methods: The generation of waste should be avoided or minimized wherever possible. Empty containers or liners may retain some product residues. This material and its container must be disposed of in a safe way. Dispose of surplus and non-recyclable products via a licensed waste disposal contractor. Disposal of this product, solutions and any by-products should at all times comply with the requirements of environmental protection and waste disposal legislation and any regional local authority requirements. Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.