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Diss Factsheets
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EC number: 601-238-3 | CAS number: 113163-37-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
The stability of the substance was determined according to the OECD guideline 111 and the EU method, C. 7 (Currenta, 2009). Based on kinetic parameters, the following dissipation half-lives for a temperature of 25 °C were extrapolated based on the Arrhenius equation:
pH 4 (25 °C): > 1 year
pH 7 (25 °C): 745 days
pH 9 (25 °C): 20 days.
Key value for chemical safety assessment
Additional information
The hydrolysis behaviour of the substance was assessed in a study conducted to a high standard, in full compliance with all three tiers of the OECD guideline 111 and the EU method C.7. The kinetic parameters were followed using a HPLC/UV method.
As the substance is a NLP containing different molecular weight fractions (= NLP-fraction) which were not completely individually identified, half-life determinations were calculated for seven main NLP-fractions representing 88 % of the substance.
The stability of the substance is found to decrease with increasing pH-value. At pH 4 and 50 °C the substance is found to be stable. Therefore it can be assumed that the substance is also stable at 25 °C and no half-life time and hydrolysis rate were calculated. The half-life time for the substance at pH 7 is 745 days and at pH 9 is 20 days, both at 25 °C.
As the hydrolysis reaction of a NLP is very complex, resulting in a sum of hydrolysis products, a clear identification of the hydrolysis products is complicated. The NLP molecules having different chain lengths even at the different carboxylic acid groups within the same molecule and may hydrolyse following different reaction kinetics. Shorter chain molecules could be already part of the NLP and could also be newly built by hydrolysis of longer chain molecules. These shorter chains may hydrolyse also.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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