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EC number: 268-215-4 | CAS number: 68037-92-3 This substance is identified by SDA Substance Name: C16-C22 alkyl amine and SDA Reporting Number: 21-029-00.
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The toxicity of C16-22 alkylamine was tested on Danio Rerio in accordance with OECD 203 in natural river water.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 3.54 mg/L
Additional information
The acute toxicity of the test item C16-22-(even numbered)-alkylamines (batch no.:S-001453) to fish (zebrafish) was determined according to OECD-Guideline for Testing of Chemicals No. 203 (1992) during June 2013.
A
semi-static test with renewal of the test media after 48 h was performed
with the nominal concentrations of0.625
- 1.25 - 2.50 - 5.00 - 10.0 mg/L.
Duration of the test was 96 hours. 7 test organisms were exposed to each
concentration level and the control. Water quality parameters pH-value,
temperature and oxygen-saturation, measured after 0, 24, 48, 72 and
96 h, were determined to be within the acceptable limits.
The test itemC16-22-(even numbered)-alkylamineshas a low water solubility and sorbs to organic and inorganic materials by different mechanisms. The sorption processes are mostly non-linear, means are concentration dependent. Due to these properties the test item is difficult to test in artificial water (e.g. sorption to the test organisms and glass walls of the test vessels) and results deriving from such tests depend on the test settings applied. Using natural river water which contains particulate as well as dissolved organic carbon to which the test item can sorb partially reduces the difficulties encountered in tests with synthetic water (e.g. preventing that the test item settles onto surfaces). The sorbed fraction of the test item was difficult to extract from the test system which normally leads to low analytical recoveries.Due to the short exposure period, these low analytical recoveries cannot be associated to biodegradation. This means that the test substance was for more than 80 % present in the test system and therefore available for exposure (dissolved in water and sorbed also called bulk). This so called Bulk Approach is described by ECETOC (2003). Due to the full exposure of the organisms the test item nominal concentrations were used to base the dose response on instead of measured ones.
All effect levels are given based on nominal concentrations of C16-22-(even numbered)-alkylamines. The test item C16-22-(even numbered)-alkylamines was found to be toxic to zebrafish after 96 h. At the nominal test item concentration of 2.50 mg/L no mortality or non lethal effects were observed. Therefore the NOEC was laid down as 2.50 mg/L. The LC50 after 96 hours is 3.54 (2.50 – 5.00) mg/L.
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