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Diss Factsheets
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EC number: 264-637-8 | CAS number: 64051-50-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Under the conditions of the test, there were no statistically significant effects on respiration observed during the definitive test. The 3 hour EC50 for the test material was greater than 320 mg/L. The NOAEC value was determined to be 320 mg/L, the highest concentration tested.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 320 mg/L
- EC10 or NOEC for microorganisms:
- 320 mg/L
Additional information
The potential of the test material to cause toxic effects to microorganisms was investigated in accordance with the standardised guideline OECD 209 under GLP conditions. The study was awarded a reliability score of 1 in accordance with the criteria of Klimisch (1997).
The activated sludge inoculum was collected from a sludge return line which has a predominantly domestic sewage catchment. The point of collection was to ensure that the activated sludge sample was relatively free of exogenous material. A range-finder test, employing nominal test material concentrations of 1, 10, 100 and 1000 mg/L, was undertaken to determine the appropriate concentration levels for a definitive test. The range-finding test showed limited inhibition ( less than 30%) of total, heterotrophic and nitrification respiration at 10 and 100 mg/L, but negative inhibition was observed at both 1 and 1000 mg/L.
Based on the results of the range-finding test, a 3 hour definitive toxicity test was conducted at concentrations of 3.05, 9.77, 31.25, 100 and 320 mg/L. Reference substance inhibition, blank control respiration rate and the coefficient of variation between replicates were observed to be within the validity criteria. The results of the definitive test can therefore be considered to be valid. As enhancement effects were noted (observed as negative inhibition), the endpoints are reported as EC50 and No Observed Adverse Effect Concentration (NOAEC).
Under the conditions of the test, there were no statistically significant effects in heterotrophic, nitrification or total respiration inhibition observed during the definitive test. The 3 hour EC50 for the test material was greater than 320 mg/L. The NOAEC value was determined to be 320 mg/L, the highest concentration tested.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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