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EC number: 260-829-0 | CAS number: 57583-35-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Solubility in organic solvents / fat solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- solubility in organic solvents / fat solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 22 February 2020
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study
- Qualifier:
- according to guideline
- Guideline:
- other: Commission Regulation (EC) No 440/2008 (as amended)
- Version / remarks:
- 30 May 2008
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: OECD Guidelines for Testing of Chemicals
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: CIPAC Handbook for the Analysis of Technical and Formulated Pesticides
- Deviations:
- no
- GLP compliance:
- yes
- Key result
- Medium:
- n-octanol
- Solubility:
- > 250 g/L
- Temp.:
- 20 °C
- Test substance stable:
- not determined
- Details on results:
- The solubility of the test material in n-octanol was determined to be greater than 250 g/L of solution at 20.0 ± 0.5 °C.
- Conclusions:
- Under the conditions of the study the solubility of the test material in n-octanol was determined to be greater than 250 g/L of solution at 20.0 ± 0.5 °C.
- Executive summary:
The n-octanol solubility of the test material has been determined by a visual evaluation method designed to be compatible with the CIPAC Handbook for the Analysis of Technical and Formulated Pesticides, Book H, Method MT 181 and in compliance with GLP.
Under the conditions of the study the solubility of the test material in n-octanol was determined to be greater than 250 g/L of solution at 20.0 ± 0.5 °C.
Reference
Preliminary Test
The total volume of solvent needed to dissolve the test item sample for the preliminary test, and the resulting solubility result, is shown in the following table.
Preliminary Test Result
Mass of Test Material (g) |
Total Volume of Solvent to Achieve Dissolution (mL) |
Solubility Result (g/L) |
0.1059 |
0.5 |
>200 |
Definitive Test
The total volume of n-octanol needed to dissolve the test material, and the resulting solubility results, are shown in the following table.
Definitive Test Result
Replicate |
Mass of Test Material (g) |
Total Volume of Solvent to Achieve Dissolution (mL) |
Solubility (g/L) |
Overall Solubility (g/L) |
A |
0.5070 |
2.0 |
>253 |
> 250 |
B |
0.5023 |
2.0 |
>251 |
Evaluation of Data
For the definitive tests, the solubility results were obtained as detailed in the following table, based on the initial nominal mass of test material taken and the total volume of relevant solvent needed to achieve complete dissolution of the test material.
Total volume required for complete dissolution (mL) |
Solubility (g/L) |
|||
(0.5 g) |
(0.4 g) |
(0.2 g) |
(0.1 g) |
|
2.0 |
>250 |
>200 |
>100 |
>50 |
2.5 |
200-250 |
160-200 |
80-100 |
40-50 |
3.0 |
167-200 |
133-160 |
67-80 |
33-40 |
3.5 |
|
114-133 |
57-67 |
29-33 |
4.0 |
|
100-114 |
50-57 |
25-29 |
5.0 |
|
80-100 |
40-50 |
20-25 |
7.0 |
|
|
29-40 |
14-20 |
10.0 |
|
|
|
10-14 |
Description of key information
Under the conditions of the study the solubility of the test material in n-octanol was determined to be greater than 250 g/L of solution at 20.0 ± 0.5 °C.
Key value for chemical safety assessment
- At the temperature of:
- 20 °C
- Solubility in organic solvents at 20°C:
- 250 g/L
Additional information
The n-octanol solubility of the test material has been determined by a visual evaluation method designed to be compatible with the CIPAC Handbook for the Analysis of Technical and Formulated Pesticides, Book H, Method MT 181 and in compliance with GLP. The study was awarded a reliability score of 1 in accordance with the criteria set forth by Klimisch et al. (1997).
Under the conditions of the study the solubility of the test material in n-octanol was determined to be greater than 250 g/L of solution at 20.0 ± 0.5 °C.
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