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EC number: 252-652-2 | CAS number: 35642-64-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Appearance / physical state / colour
The appearance of 7-[[2-[(aminocarbonyl)amino]-4-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]phenyl]azo]naphthalene-1,3,6-trisulphonic acid was observed as, solid organic compound.
Melting point/ Freezing point
Based on prediction done using MPBPVP v1.43, the melting point of chemical 7-[[2-[(aminocarbonyl)amino]-4-[(4-amino-6-chloro-1,3,5 -triazin-2-yl)amino] phenyl]azo]naphthalene-1,3,6-trisulphonic acid was estimated to be 349.84 ˚C.
Boiling point
According to Column II of Annex VII of REACH regulation, the boiling point study does not need to be conducted because the substance 7-[[2-[(aminocarbonyl)amino]-4-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]phenyl]azo]naphthalene-1,3,6-trisulphonic acid (CAS No.35642-64-9) is a solid at room temperature which also melts above 300°C. Hence, it is not feasible to determine boiling point of the substance and hence the endpoint was considered for waiver.
Density
The density of chemical 7-[[2-[(aminocarbonyl)amino]-4-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]phenyl]azo]naphthalene-1,3,6 -trisulphonic acid was estimated to be 2.07 ± 0.1 g/cm3, at 20 °C and 760 mmHg pressure.
Particle size distribution (Granulometry)
The particle size distribution of 7-[[2-[(aminocarbonyl)amino]-4-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]phenyl]azo]naphthalene-1,3,6 -trisulphonic acid was determined by granulometric analysis with rotap sieve shaker. The particle size distribution was determined to be in the range of 51 micron to 146 micron.
Vapour pressure
The estimated vapour pressure of the substance 7-[[2-[(aminocarbonyl)amino]-4-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]phenyl]azo] naphthalene-1,3,6-trisulphonic acid at 25 deg C was 3.72E-033 Pa.
Partition coefficient
Based on the available data from modeling databases using the KOWWIN V1.68 programme, octanol water partition coefficient (log Pow) value of the test substance 7 -[(E)-2 -{4 -[(4 -amino-6 -chloro-1,3,5 -triazin-2 -yl)amino]-2 -(carbamoylamino)phenyl}diazen-1 -yl]naphthalene-1,3,6 -trisulfonic acid was estimated to be -0.66. Thus, on the basis of logPow value, chemical 7 -[(E)-2 -{4 -[(4 -amino-6 -chloro-1,3,5 -triazin-2 -yl)amino]-2 -(carbamoylamino)phenyl}diazen-1 -yl]naphthalene-1,3,6 -trisulfonic acid can be considered to be hydrophilic in nature.
Water solubility
The estimated water solubility of substance 7-[[2-[(aminocarbonyl)amino]-4-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]phenyl]azo] naphthalene-1,3,6-trisulphonic acid at 25 deg C was 1000000 mg/l.
Surface tension
The surface tension for chemical 7-[[2-[(aminocarbonyl)amino]-4-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]phenyl]azo] naphthalene-1,3,6-trisulphonic acid was predicted to be 110.4 ± 7.0 dyne/cm.
Flash point
The study does not need to be conducted because the flash point is only relevant to low melting point solids, and the test chemical 7-[[2 -[(aminocarbonyl)amino]-4-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]phenyl]azo]naphthalene-1,3,6-trisulphonic acid has melting point is above 300°C i.e at 349.84°C, hence this study considerd to be waiver.
Autoflammability
7-[[2-[(aminocarbonyl)amino]-4-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]phenyl]azo]naphthalene-1,3,6-trisulphonic acid did not catch fire on being exposed to air at room temperature of 27°C pressure of 966 hPa. This indicates that 7-[[2-[(aminocarbonyl)amino]-4-[(4-amino-6 -chloro-1,3,5-triazin-2-yl)amino]phenyl]azo]naphthalene-1,3,6-trisulphonic acid is not auto-flammable.
Flammability
7-[[2-[(aminocarbonyl)amino]-4-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]phenyl]azo]naphthalene-1,3,6-trisulphonic acid does not indicate any ignition when the flame of bunsen burner having temperature of approximately 950°C is brought in contact with it. Thus it can be concluded that 7-[[2-[(aminocarbonyl)amino]-4-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]phenyl]azo]naphthalene-1,3,6-trisulphonic acid is not flammable at high temperature. However since such high temperatures are not found under normal circumstances of transportation and use, thus 7-[[2-[(aminocarbonyl)amino]-4-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]phenyl]azo]naphthalene-1,3,6-trisulphonic acid was considered non-flammable for chemical safety assessment.
Explosiveness
Based on the screening procedure followed, the substance 7-[[2-[(aminocarbonyl)amino]-4-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]phenyl] azo]naphthalene-1,3,6-trisulphonic acid (CAS No.- 35642-64-9) is considered to have marginal explosive properties and hence classified under explosive Division 1.6 based on CLP criteria.
Oxidising properties
The study does not need to be conducted because there are no chemical groups present in the molecule which are associated with oxidizing properties and hence the classification procedure does not need to be applied.
Additional information
Appearance / physical state / colour
Based on available data from obtained report, the appearance of 7-[[2-[(aminocarbonyl)amino]-4-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]phenyl]azo]naphthalene-1,3,6-trisulphonic acid was observed as, solid organic compound.
Melting point/ Freezing point
Based on the prediction done using the EPI Suite MPVPBP V1.43, the melting point of chemical 7-[[2-[(aminocarbonyl)amino]-4-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]phenyl]azo]naphthalene-1,3,6-trisulphonic acid was predicted.
The melting point of chemical 7-[[2-[(aminocarbonyl)amino]-4-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]phenyl]azo]naphthalene-1,3,6-trisulphonic acid was estimated to be 349.84 ˚C.
Boiling point
According to Column II of Annex VII of REACH regulation, the boiling point study does not need to be conducted because the substance 7-[[2-[(aminocarbonyl)amino]-4-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]phenyl]azo]naphthalene-1,3,6-trisulphonic acid (CAS No.35642-64-9) is a solid at room temperature which also melts above 300°C. Hence, it is not feasible to determine boiling point of the substance and hence the endpoint was considered for waiver.
Density
Based on prediction done using ACD/I-Lab 2.0 and Scifinder, the density of chemical 7-[[2-[(aminocarbonyl)amino]-4-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]phenyl]azo]naphthalene-1,3,6-trisulphonic acid was estimated to be 2.07 ± 0.1 g/cm3, at 20 °C and 760 mmHg pressure.
Particle size distribution (Granulometry)
The particle size distribution of 7-[[2-[(aminocarbonyl)amino]-4-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]phenyl]azo]naphthalene-1,3,6 -trisulphonic acid was determined by granulometric analysis with rotap sieve shaker. The particle size distribution was determined to be in the range of 51 micron to 146 micron.
Vapour pressure
Modified Grain method (Mean of Antoine and Modified Grain methods) was used to estimate the vapour pressure of the substance 7-[[2 -[(aminocarbonyl)amino]-4-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]phenyl]azo]naphthalene-1,3,6-trisulphonic acid using MPBPVP v1.43 of EPI SUITE.
The estimated vapour pressure of the substance 7-[[2-[(aminocarbonyl)amino]-4-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]phenyl]azo] naphthalene-1,3,6-trisulphonic acid at 25 deg C was 3.72E-033 Pa.
Partition coefficient
Based on the available data from modeling databases using the KOWWIN V1.68 programme, octanol water partition coefficient (log Pow) value of the test substance 7 -[(E)-2 -{4 -[(4 -amino-6 -chloro-1,3,5 -triazin-2 -yl)amino]-2 -(carbamoylamino)phenyl}diazen-1 -yl]naphthalene-1,3,6 -trisulfonic acid was estimated to be -0.66. Thus, on the basis of logPow value, chemical 7 -[(E)-2 -{4 -[(4 -amino-6 -chloro-1,3,5 -triazin-2 -yl)amino]-2 -(carbamoylamino)phenyl}diazen-1 -yl]naphthalene-1,3,6 -trisulfonic acid can be considered to be hydrophilic in nature.
Water solubility
WSKOW v1.42 was used to estimate the water solubility of the substance 7-[[2-[(aminocarbonyl)amino]-4-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]phenyl]azo]naphthalene-1,3,6-trisulphonic acid. The estimated water solubility of the test substance 7-[[2-[(aminocarbonyl)amino]-4-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]phenyl]azo] naphthalene-1,3,6-trisulphonic acid at 25 deg C was 1000000 mg/l.
Based on the estimated value, the substance 7-[[2-[(aminocarbonyl)amino]-4-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]phenyl]azo] naphthalene-1,3,6-trisulphonic acid was considered to be very soluble in water.
Surface tension
Based on the prediction done by ACD labs Software (v12.1.0.50375), the surface tension for chemical 7-[[2-[(aminocarbonyl)amino]-4-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]phenyl]azo]naphthalene-1,3,6-trisulphonic acid was predicted to be 110.4 ± 7.0 dyne/cm.
Flash point
The study does not need to be conducted because the flash point is only relevant to low melting point solids, and the test chemical 7-[[2 -[(aminocarbonyl)amino]-4-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]phenyl]azo]naphthalene-1,3,6-trisulphonic acid has melting point is above 300°C i.e at 349.84°C, hence this study considerd to be waiver.
Autoflammability
7-[[2-[(aminocarbonyl)amino]-4-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]phenyl]azo]naphthalene-1,3,6-trisulphonic acid did not catch fire on being exposed to air at room temperature of 27°C pressure of 966 hPa. This indicates that 7-[[2-[(aminocarbonyl)amino]-4-[(4-amino-6 -chloro-1,3,5-triazin-2-yl)amino]phenyl]azo]naphthalene-1,3,6-trisulphonic acid is not auto-flammable.
Flammability
7-[[2-[(aminocarbonyl)amino]-4-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]phenyl]azo]naphthalene-1,3,6-trisulphonic acid does not indicate any ignition when the flame of bunsen burner having temperature of approximately 950°C is brought in contact with it. Thus it can be concluded that 7-[[2-[(aminocarbonyl)amino]-4-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]phenyl]azo]naphthalene-1,3,6-trisulphonic acid is not flammable at high temperature. However since such high temperatures are not found under normal circumstances of transportation and use, thus 7-[[2-[(aminocarbonyl)amino]-4-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]phenyl]azo]naphthalene-1,3,6-trisulphonic acid was considered non-flammable for chemical safety assessment.
Explosiveness
The screening procedure for explosive properties is based on the use of both theoretical considerations which is summarized as follows:
The substance 7-[[2-[(aminocarbonyl)amino]-4-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]phenyl]azo]naphthalene-1,3,6-trisulphonic acid (CAS: 35642 -64 -9) contains an azo group and triazine group; two of the alert groups for explosive properties. Thus, following the screening procedure, the oxygen balance was calculated. The molecular formula is C20H16ClN9O10S3 and the molecular weight is 674.0504. These give an oxygen balance of –90.200. This is more positive than the –200 threshold.
Further testing data is not available.
Thus, based on the screening procedure followed, the substance 7-[[2-[(aminocarbonyl)amino]-4-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]phenyl]azo]naphthalene-1,3,6 -trisulphonic acid(CAS: 35642 -64 -9)is considered to have marginal explosive properties and hence classified under explosive Division 1.6 based on CLP criteria.
Oxidising properties
The study does not need to be conducted because there are no chemical groups present in the molecule which are associated with oxidizing properties and hence the classification procedure does not need to be applied.
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