Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 236-942-6 | CAS number: 13557-75-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2018-06-22 to 2018-09-19
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- GLP compliance:
- no
- Type of method:
- flask method
- Specific details on test material used for the study:
- - Test item: Esterlac SLL
- CAS No.: 13557-75-0
- Molecular weight: 294.37 g/mol
- Sum formula: C18H31NaO6
- Identity: 64.2% aicd value, 194 saponification number
- Physical state: Light yellow paste
- Storage: 10 °C - 30 °C - Key result
- Water solubility:
- > 114 g/L
- Conc. based on:
- test mat. (dissolved fraction)
- Incubation duration:
- >= 24 - <= 72 h
- Temp.:
- 20 °C
- pH:
- 6.8
- Conclusions:
- The water solubility of the test item at 20 °C was determined to be > 114 g/L (pH 6.8).
- Executive summary:
The water solubility of the test item at 20 °C was determined according to OECD 105 using the flask method. The water solubility was determined to be > 114 g/L (pH 6.8).
Reference
Preliminary test
In a stepwise procedure, increasing volumes of demineralised water were added at room temperatue to a defined amount of the test item. After each addition the mixture was treated with ultrasound for 10 minutes and visually checked for any undissolved particles (Table 1). The preliminary test showed that the water solubility of the test item is > 10 mg/L. Accordingly, the water solubility was determined by the flask method in the main test.
Table 1: Results of the preliminary test
Amount of test item / mg |
Added volume of demineralised water / mL |
Total volume of demineralised water / mL |
Appearance of mixture |
106.1 |
0.1 |
0.1 |
Not dissolved |
0.4 |
0.5 |
Not dissolved |
|
0.5 |
1.0 |
Not dissolved |
|
1 |
2 |
Not dissolved |
|
8 |
10 |
Dissolved (slightly turbid) |
Flask method
During stirring the solutions with the test item showed the formation of foam. After the equilibration the solutions were extremely viscous but mostly clear and no precipitate was observed. The viscous masses were centrifuged and filtered. The following preparation for the analysis needed several days (time needed for the solution to settle in a measuring cylinder for dilution). Due to the high viscosity the pH was measured after the first dilution step from approximately 2 mL (due to the high viscosity it was not possible to use exactly 2 mL, therefore the present test mixture was used (2.0 mL for 24 h experiment, 2.8 mL for 48 h experiment, 1.6 mL for 72 h experiment)) to 10.0 mL with demineralised water (this first dilution step resulted in different dilution factors for each experiment). After the first dilution step the solutions with the test item were turbid (the turbidity had no influence on the final result). Results of the water solubility experiments with the test item are summarised in Table 2.
Table 2: Water solubility experiments of the test item
Experiment |
24 h |
48 h |
72 h |
Blank experiment (72 h) |
Amount of test item / g |
2.505 |
2.517 |
2.513 |
- |
Added amount of demineralised water for the test solutions / mL |
10 |
10 |
10 |
10 |
Stirring time at 30 °C / h |
24 |
48 |
72 |
72 |
pH at ambient temperature |
6.8 |
6.8 |
6.8 |
5.7 |
Dilution factor |
5556 |
3571 |
3125 |
1000 |
Measured concentration* / mg/L |
19.62 / 19.84 |
34.80 / 35.64 |
33.89 / 33.69 |
- / - |
Mean concentration / mg/L |
19.73 |
35.22 |
33.79 |
- |
Water solubility / g/L |
109.6 |
125.8 |
105.6 |
- |
*under consideration of an estimated carbon content of 61.2 % (molecular mass 294.4 g/mol, containing 15 carbon atoms) for the test item and without correction of the purity.
The water solubility of the test item at 20 °C was determined to be > 114 g/L (the water solubility could have been influenced by self-organisation of the test item).
The used analytical method (TOC) only detects any carbon present in the test solutions and is therefore not specific to the target molecule. Furthermore, the determination of the water solubility of the test item was associated with uncertainties (e.g. foaming, equilibrated solution very viscous, time needed for solution settling). Nevertheless, the experimental results on the solubility of the test item in water are considered adequate and therefore constitute the best possible approximation to the behaviour of the test item in water.
Description of key information
The water solubility of the test item at 20 °C was determined according to OECD 105 using the flask method. The water solubility was determined to be > 114 g/L (pH 6.8).
Key value for chemical safety assessment
- Water solubility:
- 114 g/L
- at the temperature of:
- 20 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.