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EC number: 221-112-8 | CAS number: 3006-93-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Because the test substance was not stable in the test medium, the validation was related to double hydrolysed product (main hydrolytic product, which is more stable in the dilution water) according to Guidance Document on Aquatic Toxicity Testing of Difficult Substances and Mixtures (OECD SERIES ON TESTING AND ASSESSMENT No. 23). The analytical determination of the test substance concentrations will also be based on this double hydrolysed product.
Because concentrations of the double hydrolysed product (in the two highest concentrations) have not been satisfactorily maintained within ± 20 percent of the nominal or measured initial concentration throughout the test, geometric means of measured concentrations were used for evaluations and results.
The evaluation using geometric means of measured concentrations:
72 hour - ErC50 = not evaluated (95% confidence limit: not evaluated)
72 hour - EyC50 = 2.81 mg· L-1 (95% confidence limit: 0.187 - 47.8 mg· L-1)
72 hour - ErC10 = 0.308 mg· L-1 (95% confidence limit: 0.078 - 1.22 mg· L-1)
72 hour - EyC10 = 0.007 mg· L-1 (95% confidence limit: 0.00 I -0.096 mg· L-1)
72 hour - NOECr < 3.26 mg· L-1
72 hour - NOECy < 3.26 mg· L-1
In addition, there was a deviation in the process of evaluating data in this test. At the calculation of the geometric mean of measured concentrations it is showed that the value of highest concentration (100 mg/L) is lower than the second highest concentration (56 mg/L) . For this reason, in the calculation of EC value the highest concentration was excluded, then the statistical software ToxRat Professional Version 3.2.1. was not able to calculate the value of 72 hour ErC50 (due to low inhibition). In this case, considering the inhibition, we temporarily consider the ErC50 is > 55.5 mg/L(geometric mean measured concentration of the second highest concenteation).
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 55.5 mg/L
- EC10 or NOEC for freshwater algae:
- 0.308 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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