Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 215-127-9 | CAS number: 1304-28-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Long-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- long-term toxicity to aquatic invertebrates
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Not conducted according current guideline but study well documented and meeting generally accepted scientific principles
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Effects of various metals on survival, growth, reproduction and metabolism of Daphnia magna
- Author:
- Biesinger K. E. and Christensen G. M.
- Year:
- 1 972
- Bibliographic source:
- Journal fisheries Research Board of Canada, Vol. 29 No. 12, 1972
- Reference Type:
- secondary source
- Title:
- Barium and Barium Compounds
- Author:
- World Health Organization
- Year:
- 2 001
- Bibliographic source:
- Concise International Chemical Assessment Document 33. World Health Organisation (Geneva)
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 211 (Daphnia magna Reproduction Test)
- GLP compliance:
- no
Test material
- Reference substance name:
- Barium chloride
- EC Number:
- 233-788-1
- EC Name:
- Barium chloride
- Cas Number:
- 10361-37-2
- IUPAC Name:
- barium dichloride
Constituent 1
Sampling and analysis
- Analytical monitoring:
- not specified
Test solutions
- Vehicle:
- no
- Details on test solutions:
- The number of concentrations tested ranged from 5 to 12 dependent on the toxicant and the initial effects observed.
Test organisms
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- - Strain: laboratory clone
- Source: University of Michigan
- Age at study initiation (mean and range, SD): 12h +/- 12h
Study design
- Test type:
- semi-static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 21 d
Test conditions
- Hardness:
- Mean: 45.3 mg/L (Range: 44.0 - 53.0)
- Test temperature:
- 18 +/- 1 °C
- pH:
- Mean: 7.74 (Range: 7.4 - 8.2)
- Dissolved oxygen:
- Near saturation
- Details on test conditions:
- Five Daphnids were placed in 200 mL of water in 250-mL beaker. Four beaker (the test chambers) were used with a total of 20 animals for each experimental and control condition for each test. The test chambers were covered with a pane of glass to minimize evaporation and distributed randomly in a constant temperature room.. Young daphnids were placed in test chambers into new medium at the beginning of each week and subjected to test conditions for 3 weeks. Survival of the initial animals was noted after1, 2 and 3 weeks. At the end of three weeksthe surviving animals were weighed and prepared for protein and GOT analyses. Reproduction was assessed by counting the young produced each week. Light intensity of about 115 ft-c at the water interface was provided. An automatically controlled16-hr photoperiod was used.
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 21 d
- Dose descriptor:
- EC50
- Effect conc.:
- 8.9 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- element
- Basis for effect:
- reproduction
- Duration:
- 21 d
- Dose descriptor:
- other: EC16
- Effect conc.:
- 5.8 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- element
- Basis for effect:
- reproduction
- Reported statistics and error estimates:
- Results were statistically evaluated with the method of Lichtfield and Wilcoxon (1949) for establishing appoximations of the 95% confidence limit for survival. Reproductive effects were analyzed in a similar manner excluding confidence limits, but are given in terms of reproductive impairment by percentage. Both 50% and 16% reproduction-impairments are given. These values imply decreases in the total number of youngproduced as compared with the control. The 16% reproductive-impairment concentration is given since it represented a minimal reproducible value below which the variability in reproduction could not be detected from controls.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.