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Diss Factsheets
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EC number: 209-665-3 | CAS number: 589-92-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Density
Administrative data
Link to relevant study record(s)
- Endpoint:
- density, other
- Remarks:
- density
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- 1993
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
- Remarks:
- Purity specified. No details on experimental method or setup reported.
- Principles of method if other than guideline:
- no information on method in publication.
- GLP compliance:
- no
- Type of method:
- other: no information available
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: Merck
- Purity: "high purity", >99% - Key result
- Type:
- density
- Density:
- 0.916 g/cm³
- Temp.:
- 20 °C
- Conclusions:
- The density for 4-Methycylohexanone at 293.15K (20°C) was reported to be 0.91641 g/cm^3. No details on the experimental density determination were reported.
- Executive summary:
The density of 4 -methycylohexanone (>99%) at 293.15 K was reported as 0.91641 g/cm^3.
- Endpoint:
- relative density
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- 1938
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
- Remarks:
- No details on the method used or experimental setup. Some details on sample purification provided.
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- No information on the method used was reported.
- GLP compliance:
- no
- Type of method:
- other: method not reported
- Specific details on test material used for the study:
- Commercially available 4-Methylcyclohexanone was purified as follows:
4-Methylcyclohexanone was treated with a freshly prepared oversaturated filtered solution of sodium hydrogene sulfite. After shaking strongly for 3 hours the system was frozen. The next day, the solid parts were dried and washed extensively with cold ether. As soon as dried, the bisulfite derivates were decomposed with sodium carbonate. The 4-methylcyclohexanone released was rectified systematically by powerful Crismer Columns (35 spires) with external heating. - Key result
- Type:
- relative density
- Remarks:
- D20/4
- Density:
- 0.916
- Temp.:
- 20 °C
- Type:
- relative density
- Remarks:
- D0/4
- Density:
- 0.932
- Temp.:
- 0 °C
- Conclusions:
- The relative density (dimentionless) of 4-Methylcyclohexanone at 20°C was reported as 0.9156. No details on the method used were provided.
- Executive summary:
The relative density of 4-Methylcyclohexanone at 20°C was reported as 0.9156.
- Endpoint:
- relative density
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
- Remarks:
- Some details on purification. Experimental details in reference.
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Densities were measured over a range of temperatures as decribed in "Part II (loc. cited)".
- GLP compliance:
- no
- Type of method:
- other: Information on the method provided in references.
- Specific details on test material used for the study:
- 4-Methylcyclohexanone was purified through the semicarbazone (m.p.197°C). Boiling point reported as 170°C at 761mmHg.
- Key result
- Type:
- relative density
- Remarks:
- D20/4
- Density:
- 0.914
- Temp.:
- 20 °C
- Conclusions:
- The density of 4-Methylcyclohexanone is 0.9145 at 20 °C
- Executive summary:
The density of 4-Methylcyclohexanone is 0.9145 at 20 °C
No information about the method is given.
Referenceopen allclose all
The publication reports the temperature in Kelvin.
Further density results reported: at 15°C: 0.9198 and at 30°C: 0.9072.
Relative densities determined at 20°C: 0.9145, 23.2°C: 0.9120, 60.5°C: 0.8835, 60.9°C: 0.8832, 85.9°C: 0.8269.
The relative density at 20°C was calculated from the observed densities assuming a linear correlation with temperature.
Description of key information
Three representative publications were selected from the available literature reporting the density / relative density for 4-methylcyclohexanone:
0.91641g/cm^3, 20°C, no method reported, (Aucejo, 1993)
0.9156, D20/4, no method reported, (Chiurdoglu, 1938)
0.9145, D20/4, no method reported, (Vogel, 1938)
All three primary data sources were assigned a Klimisch reliability rating of 4, due to the lack of experimental details reported in the publications. The values reported by the three independent research groups, measured on independently synthesised samples, at different times, are all in good agreement. As a result, in accordance with REACH, Annex XI, 1.2, this standard data requirement is considered to be met based on the weight of evidence. Overall the available data is considered to be adequate, relevant, and reliable, and no further testing is required for this endpoint. The most recently measured value (Aucejo, 1993) was taken forward (dimentionless, assuming density at 4°C = 1g/cm^3) for the purposes of risk assessment.
Key value for chemical safety assessment
- Relative density at 20C:
- 0.916
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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