Registration Dossier

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2014
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: In accordance with OECD and EU protocol and GLP methods..

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2014
Report Date:
2014

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
EU Method A.6 (Water Solubility)
Qualifier:
according to
Guideline:
other: OECD Guidelines for Testing of Chemicals
GLP compliance:
yes (incl. certificate)
Type of method:
flask method

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: particulate/powder
Remarks:
migrated information: powder
Details on test material:
-Chemical Name: 6-hydroxy-2-naphthaleneboronic acid
- Substance type: off white powder
- Physical state: solid
- Storage condition of test material: room temperature, in the dark (08 October 2013) Approximately 4° C in the dark (onwards)
- Date received: 08 October 2013

Results and discussion

Water solubility
Water solubility:
ca. 1.08 g/L
Temp.:
20 °C
pH:
>= 6.02 - < 6.74
Details on results:
The preliminary estimate of water solubility was 1.08 g/L at 20.0 ± 0.5 °C. See attachment below entitled "Definitive test results" for the results

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information): soluble (1000-10000 mg/L) 1.08g/L
The water solubility of the test item, Boronic Acid has been determined to be 1. 08 g/L of solution at 20.0 ± 0.5 °C.
Executive summary:

The water solubility of Boronic Acid was determined using the flask method, designed to be compatible with Method A6 Water Solubility of Commission Regulation (EC) no 440/2008 of 30 May 2008 amd Method 105 of the OECD Guidelines for Testing of Chemicals, 27 July 1995. It was determined to be 1. 08 g/L of solution at 20.0 ± 0.5 °C.