Registration Dossier
Registration Dossier
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EC number: 248-256-4 | CAS number: 27138-01-8
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
The hydrolysis of m/p-Diol was assessed in aqueous buffers at pH 4, 7 and 9 at 50 ± 0.5 °C. After 5 days the test item was shown to have hydrolysed by less than 10% at each pH (equivalent to half-life 25°C >1 year). This indicated that the test item was hydrolytically stable and significant hydrolysis had not occurred at environmentally relevant pH.
Key value for chemical safety assessment
Additional information
The hydrolysis of m/p diol was evaluated in a study performed in accordance with OECD testing guideline 111 and GLP requirements, however, Standard tests for hydrolysis are not typically appropriate for the test item since m/p-Diol is present as a mixture. Therefore the two principle components of the test item were used as tracer peaks for determination of rate of hydrolysis. It is likely that similar hydrocarbon components of the test item would exhibit similar hydrolytic behaviour.
The hydrolysis of m/p-Diol was assessed in aqueous buffers at pH 4, 7 and 9 at 50 ± 0.5 °C. After 5 days the test item was shown to have hydrolysed by less than 10% at each pH (equivalent to half-life 25°C >1 year). This indicated that the test item was hydrolytically stable and significant hydrolysis had not occurred at environmentally relevant pH.
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