Registration Dossier

Administrative data

Endpoint:
toxicity to reproduction
Remarks:
other: QSAR
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
1 (reliable without restriction)
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6

Data source

Reference
Reference Type:
other: QSAR
Title:
RBA Multicase
Author:
OECD QSAR Toolbox
Year:
2010
Bibliographic source:
OECD QSAR Toolbox

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 422 (Combined Repeated Dose Toxicity Study with the Reproduction / Developmental Toxicity Screening Test)
Principles of method if other than guideline:
QSAR
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Results: P0 (first parental animals)

Effect levels (P0)

Dose descriptor:
other: QSAR prediction
Effect level:
0 other: %
Based on:
not specified
Sex:
not specified
Remarks on result:
not measured/tested

Results: P1 (second parental generation)

Effect levels (P1)

Dose descriptor:
other: QSAR prediction
Based on:
not specified
Sex:
not specified
Remarks on result:
other: Generation
Remarks:
QSAR prediction (migrated information)

Results: F1 generation

Effect levels (F1)

Dose descriptor:
other: QSAR prediction
Effect level:
0 mg/kg bw/day (nominal)
Sex:
not specified
Basis for effect level:
other: QSAR prediction

Overall reproductive toxicity

Reproductive effects observed:
not specified

Applicant's summary and conclusion

Conclusions:
not toxic to reproduction