Registration Dossier
Registration Dossier
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EC number: 448-250-3 | CAS number: -
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
AF-654 is not readily biodegradable (4% after 29 days) (OECD 301B)
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
The potential of 2 -Hexyl-2 '-hydroxy-5 'methyldecananilide (AF-654) for ready biodegradability was investigated in a study by Desmares-Koopmans (2003). This test was performed according to EU Method C.4-C and OECD Guideline 301B under GLP conditions. The test substance was incubated, at a concentration of 15.5 mg/L (12 mg TOC/L), with activated sludge for 29 days at 21.9 - 23.1 °C. At the end of the test, AF-654 reached 4% biodegradation (mean value of two replicates). Since the pass level of 60% was not achieved, the test substance is considered to be not readily biodegradable. The results from the toxicity control containing test and reference substance (25% biodegradation within 14 days) indicate that AF-654 is not inhibitory to microorganisms’ activity.
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