Registration Dossier

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2019
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Report Date:
2019

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
Version / remarks:
July 27, 1995
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.6 (Water Solubility)
Version / remarks:
March 04, 2016
Deviations:
no
Qualifier:
according to
Guideline:
EPA OPPTS 830.7840 (Water Solubility)
Version / remarks:
March 1998
Deviations:
no
GLP compliance:
yes
Type of method:
flask method

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Water solubility
Key result
Water solubility:
2.14 g/L
Conc. based on:
test mat.
Loading of aqueous phase:
14.5 g/L
Incubation duration:
72 h
Temp.:
20 °C
pH:
>= 3.6 - <= 3.7
Details on results:
The maximum difference of the concentrations determined in the 24, 48 and 72 hour test samples was ≤ 15%. Based on this, the water solubility of the test item is given as the mean value of the analyzed concentrations.

Any other information on results incl. tables

Water Solubility of the Test Item

Stirring time

[hours]

Analyzed concentration
[g/L]

Mean

[g/L]

Maximum difference
[%]

pH

 

 

 

 

 

24

2.15

2.14

4.3

3.6

 

 

 

 

 

48

2.17

 

 

3.6

 

 

 

 

 

72

2.08

 

 

3.7

 

 

 

 

 

Applicant's summary and conclusion

Conclusions:
The flask method was applied for the determination of the water solubility of V173671.
The water solubility of the test item at 20°C was 2.14 g/L.
The pH of the aqueous samples was 3.6 and 3.7.