α,α,α-trifluorotoluene

Boiling point

Link to relevant study record(s)

Reference

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

from 2018-11-22 to 2019-02-04

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling Point)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7220 (Boiling Point / Boiling Range)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

differential scanning calorimetry

Remarks:

and Capillary method

Key result

Boiling pt.:

102.9 °C

Atm. press.:

>= 99.24 - <= 99.41 kPa

Decomposition:

no

Appearance of the Samples

Before the test the appearance of the test item was colourless liquid. After the experiments the test item was evaporated from the crucible.

Results – DSC method

Using a linear heating rate of 10 °C/min the boiling point of the test item was determined to be in the range of 86.8 – 100.9 °C (359.9 – 374.0 K) at atmospheric pressure (101.17 kPa).

Table 1. Summary of the DSC Test of Test Item

	Experiment 1	Experiment 2	Mean
Onset of effect [°C]	91.15	82.44	86.80
Endset of effect [°C]	103.15	98.57	100.86

 

Supplementary Test – Capillary method

The apparatus was checked with ultrapure water. The literature boiling point of water is 100 °C. The measured value corresponded to the literature value. The boiling point of water was determined to be 100.3 °C (373.5 K). Measured values were determined to be in the required range (literature value ± 0.5 °C).

Capillary method - Preliminary Test

Preliminary test with the test item was performed before the main test.

Table 2. Preliminary Test– capillary method

Start temperature, °C	Heating rate, °C/min	Atmospheric pressure, kPa (at the measuring)	Boiling point, °C (at standard atmospheric pressure)
25	5	99.56	102.3

 

Capillary method – Main test

For the main study the metal block was heated to 92 °C. The capillaries containing the test item were placed into the apparatus and the temperature was raised at 0.5 °C/min heating rate until the boiling temperature was reached. Three tests were carried out. The boiling point was determined to be 102.9 ± 0.57 °C (95 % confidence interval) i.e. 376.1 K. At the end of the measurements the colour of the samples became slightly yellow.

Table 3. Determination of the Boiling Point of the test item by capillary method

Atmospheric pressure, kPa (at the measuring)	Boiling point, °C (at standard atmospheric pressure)
99.41	102.8
99.33	103.2
99.24	102.8
Mean:	102.9
RSD (CV %):	0.2
Conf.int. (95 %)	0.57

 

Conclusions:

The boiling point of the test item was determined with DSC and capillary method to be 102.9 °C at atmospheric pressure.

Executive summary:

A study was conducted according to OECD TG 103, Regulation (EC) No 440/2008 method A.2 and EPA OPPTS 830.7220 to determine the boiling point of the test item using differential scanning calorimetry. The test item was weighed out into a 40 µL aluminium crucible under an inert atmosphere (nitrogen). Two tests were performed. As reference crucible, an empty aluminium crucible was used. The crucibles were heated from room temperature up to 500 °C at a constant heating rate of 10 °C/min. The appearance of the test item was noted before and after the test. A supplementary test using the capillary method was performed with the test item. A preliminary and a main test using this method were performed. In the DSC measurement the boiling point was determined to be in the range of 86.8 – 100.9 °C (359.9 – 374.0 K) at atmospheric pressure (101.17 kPa). According to the supplementary test with capillary method the boiling point was determined to 102.9 °C (376.1 K) at 99.41 kPa.

Description of key information

The boiling point of the test item was determined with DSC and capillary method to be 102.9 °C at atmospheric pressure.

Key value for chemical safety assessment

Boiling point at 101 325 Pa:

102.9 °C

Additional information

A study was conducted according to OECD TG 103, Regulation (EC) No 440/2008 method A.2 and EPA OPPTS 830.7220 to determine the boiling point of the test item using differential scanning calorimetry. The test item was weighed out into a 40 µL aluminium crucible under an inert atmosphere (nitrogen). Two tests were performed. As reference crucible, an empty aluminium crucible was used. The crucibles were heated from room temperature up to 500 °C at a constant heating rate of 10 °C/min. The appearance of the test item was noted before and after the test. A supplementary test using the capillary method was performed with the test item. A preliminary and a main test using this method were performed. In the DSC measurement the boiling point was determined to be in the range of 86.8 – 100.9 °C (359.9 – 374.0 K) at atmospheric pressure (101.17 kPa). According to the supplementary test with capillary method the boiling point was determined to 102.9 °C (376.1 K) at 99.41 kPa.