Registration Dossier
Registration Dossier
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EC number: 604-942-9 | CAS number: 15414-04-7
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Deviations:
- yes
- Remarks:
- without impact on the study results
- GLP compliance:
- yes
Test material
- Reference substance name:
- Copper, diamminebis(nitrato-kO)
- EC Number:
- 604-942-9
- Cas Number:
- 15414-04-7
- Molecular formula:
- CuH6N4O6
- IUPAC Name:
- Copper, diamminebis(nitrato-kO)
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- Inoculum prepared from activated sludge receiving predominantly domestic sewage, not pre-adapted to the test item.
- Duration of test (contact time):
- ca. 28 d
Initial test substance concentrationopen allclose all
- Initial conc.:
- 49.5 mg/L
- Initial conc.:
- 99.1 mg/L
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- O2 consumption
Reference substance
- Reference substance:
- aniline
Results and discussion
% Degradation
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 0
- Sampling time:
- 28 d
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- The pass level for ready biodegradability is 60% of ThOD. This value has to be reached in a 10-day window within the 28-day of the test (the 10-day window begins when the degree of biodegradation has reached 10% ThOD).
No biodegradation was observed for the test item after 28 days of incubation, criteria for good evidence of “ready biodegradability” were not reached under test conditions.
Therefore, the test item “MNP-363” cannot be considered as readily biodegradable according to the OECD Guideline 301 for the testing of chemicals.
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