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Physical & Chemical properties

Melting point / freezing point

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Reference
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From 03/07/2012 to 24/07/2012
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Remarks:
The study was conducted according to an internationally recognised method, and under GLP. Purity is specified. Therefore full validation applies.
Qualifier:
according to
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Deviations:
no
Qualifier:
according to
Guideline:
other: BS4633; Determination of crystallizing point
GLP compliance:
yes (incl. certificate)
Remarks:
inspection 15-16/11/2011, decision 12/03/2012, signature 01/05/2012
Type of method:
method to determine freezing temperature
Specific details on test material used for the study:
Storage condition of test material: Refrigerator (between 0 and 10°C under nitrogen)
Key result
Melting / freezing pt.:
-1.5 °C

Detailed results and graphs are available in the study report.

The test material change in appearance during cooling.

accuracy +/-0.5 °C

Executive summary:

The freezing point of the test substance was determined under GLP according to BS4633 (listed in OECD 102/EU A1 guideline), crystallizing point method.

Two main runs were performed. Freezing (i.e. liquid-solid transition) occurs at the mean temperature of -1.5°C (271.5K).

Description of key information

Freezing (i.e. liquid-solid transition) occurs at the temperature of -1.5°C (271.5K).

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:
-1.5 °C

Additional information

A fully reliable experimental study, conducted according to a recognized OECD/EC method and under GLP, is available. It is considered as a key study. The result is retained as key data.