Registration Dossier
Registration Dossier
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EC number: 222-048-3 | CAS number: 3327-22-8
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0.051 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 1.64 mg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.005 mg/L
- Assessment factor:
- 100
- Extrapolation method:
- assessment factor
- PNEC marine water (intermittent releases):
- 0.164 mg/L
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 103 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 0.54 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 0.054 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 0.077 mg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
Acute and chronic aquatic toxicity test results are used in the risk assessment. Aquatic toxicity against aquatic invertebrates, fish and algae is addressed by experimental results. Chronic values are available for Daphnia and algae. As Daphnia magna was the most sensitive organism in acute toxicity tests a long-term study according to OECD 211 and GLP was conducted (Noack 2004). Within this study the lowest effect concentration was determined with a 21-d NOEC of 0.51 mg/L.
Conclusion on classification
In acute aquatic toxicity tests the effect concentrations were above 1 mg/L (lowest acute EC50 is a 48-h EC50 (D. magna) of 164 mg/L). No acute classification is needed.
In a weight of evidence approach (3-chloro-2-hydroxypropyl)trimethylammonium chloride (CHPTAC) was rated as not readily biodegradable. In chronic aquatic toxicity tests, the test item revealed NOEC values ≤ 1 mg/L and ≥ 0.1 mg/L, and thus needs to be classified as hazardous to the aquatic environment in accordance with Section 4.1.2.6., Annex I of Regulation 1272/2008/EC. As the test item is not considered readily biodegradable, the relevant classification is Aquatic Chronic 2 (H411).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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