Tris(2-hydroxyethyl)ammonium chloride

Density

Link to relevant study record(s)

Reference

Endpoint:

relative density

Type of information:

experimental study

Adequacy of study:

key study

Study period:

from 2017-04-10 to 2017-04-13

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 109 (Density of Liquids and Solids)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.3 (Relative Density)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

pycnometer method

Dynamic viscosity of test material:

not applicable

Type:

density

Density:

1.354 g/cm³

Temp.:

20 °C

Key result

Type:

relative density

Density:

1.354

Temp.:

20 °C

Findings

All measured values and the corresponding calculation results are given in the following table:

Table 2: Measured values

First Determination				Error rel.	Error abs.
Temperature	19.8	°C			0.1
Density of water	0.998203	g/cm³		2.00 %	0.0002
Weighing #	m1	m2	m3	m4	m5
Item	Pycn. empty	Pycn. + H20	Pycn.+ repl. liq.	Pycn.+ test item	Pycn. + test item + repl. liq.
Mass in g	36.7408	61.6038	56.3892	43.8930	59.3742
Temperature in °C	19.8	19.8	20.0	20.2	20.0
Second Determination				Error rel.	Error abs.
Temperature	20.2	°C			0.1
Density of water	0.998203	g/cm³		0.02 %	0.0002
Weighing#	m1	m2	m3	m4	m5
Item	Pycn. empty	Pycn.+ H20	Pycn.+ repl. liq.	Pycn.+ test item	Pycn. + test item + repl. liq.
Mass in g	36.7409	61.6045	56.3854	43.8959	59.3727
Temperature in °C	19.8	20.2	20.2	20.2	20.2

Pycn. = Pycnometer; repl. liq.= replacement liquid, rel. = relative; abs. = absolute

Presentation of results

Results of the single determinations with the respective error as well as the mean value and its standard deviation are presented in the following tables:

Table 1: Results of single determinations

Determination	Density in g/cm³	Error of Determination in g/cm³
1	1.3539	0.0006
2	1.3540	0.0006

Table 2: Results - mean values

Parameter	Value	Unit	Standard Deviation	Relative Standard Deviation
Volume of pycnometer	24.91	cm³	0.0004	0.00 %
Density of test item	1.3539	g/cm³	0.0000	0.00 %
Density of test item	1353.9	kg/m³	0.0	0.00 %
Relative density of test item	1.3539		0.0000	0.00 %

Conclusions:

The density of the test item was determined to be 1.3539 ± 0.0006 g/cm³ at 20.0 ± 0.2 °C, which is the mean of two values. The relative density was the same value without unit.

Executive summary:

A study was performed in order to determine the density of test item according to OECD TG 109 and Regulation (EC) No. 440/2008, method A.3 by using the pycnometer method. The density of the test item was calculated as 1.3539 ± 0.0006 g/cm3 at 20.0 ± 0.2 °C, which is the mean of two values. Precision of the value was given as maximal error of a single determination. The standard deviation of the two values was much lower than the maximal error of a single determination, indicating that the error of the determination was lower than the calculated value. Correspondence of the values was very good. Therefore, the study was considered valid.

Description of key information

The density of the test item was determined to be 1.3539 ± 0.0006 g/cm³ at 20.0 ± 0.2 °C, which is the mean of two values.

Key value for chemical safety assessment

Relative density at 20C:

1.354

Additional information

A study was performed in order to determine the density of test item according to OECD TG 109 and Regulation (EC) No. 440/2008, method A.3 by using the pycnometer method. The density of the test item was calculated as 1.3539 ± 0.0006 g/cm3 at 20.0 ± 0.2 °C, which is the mean of two values. Precision of the value was given as maximal error of a single determination. The standard deviation of the two values was much lower than the maximal error of a single determination, indicating that the error of the determination was lower than the calculated value. Correspondence of the values was very good. Therefore, the study was considered valid (reference 4.4 -1).