Registration Dossier
Registration Dossier
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EC number: 263-502-0 | CAS number: 62314-22-1
Hydrolysis
Administrative data
Link to relevant study record(s)
- Endpoint:
- hydrolysis
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Study period:
- 2017
- Justification for type of information:
- Read-Across from (2-hydroxypropyl)trimethylammonium formate is claimed as valid for assessment of the quaternary ammonium cation, and on the basis that 2-ethylhexamoic acid does not undergo hydrolysis due to lack of hydrolysable groups.
Justification attached. - Reason / purpose for cross-reference:
- read-across source
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 111 (Hydrolysis as a Function of pH)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.7 (Degradation: Abiotic Degradation: Hydrolysis as a Function of pH)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Preliminary study:
- The preliminary study found the substance to be hydrolytically stable.
- Transformation products:
- not measured
- Key result
- pH:
- 7
- Temp.:
- 25 °C
- DT50:
- > 1 yr
- pH:
- 4
- Temp.:
- 25 °C
- DT50:
- > 1 yr
- pH:
- 9
- Temp.:
- 25 °C
- DT50:
- > 1 yr
- Validity criteria fulfilled:
- yes
- Conclusions:
- The estimated half-life at 25 °C, monitoring the hydroxypropyl, 2-, trimethylammonium content of the test item was >1 year at pH 4, 7 and 9
Reference
Description of key information
Based on a study using (2 -hydroxypropyl)trimethylammonium formate, the estimated half-life at 25 °C, monitoring the hydroxypropyl, 2 ,trimethylammonium content of the test item was >1 year at pH 4, 7 and 9. This value is selected for chemical safety assessment.
2 -Ethylhexanoic aacid is not expected to undergo hydrolysis in the environment due to the lack of hydrolyzable functional groups.
Key value for chemical safety assessment
- Half-life for hydrolysis:
- 1 yr
- at the temperature of:
- 25 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
