Registration Dossier

Physical & Chemical properties

Water solubility

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
16 February 2016 to 01 December 2016
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
column elution method
Specific details on test material used for the study:
Purity: 95.4% w/w
Batch: L002
Physical State / Appearance: Pale yellow liquid
Expiry Date: 31 December 2016
Storage Conditions: Room temperature in the dark
Key result
Water solubility:
<= 0.02 mg/L
Conc. based on:
test mat.
Temp.:
20 °C
pH:
> 5.8 - < 6.7
Remarks on result:
other: See Table 1
Key result
Water solubility:
<= 0.02 mg/L
Conc. based on:
test mat.
Temp.:
20 °C
pH:
> 6 - < 7.1
Remarks on result:
other:
Remarks:
See Table 2

Table 1        Measurements of water solubility at 20°C

Column flow rate 0.4 mL/minute 

Sample

Solubility

pH

number

(mg/L)

 

 

 

 

0.4A

< 0.02

6.7

0.4B

< 0.02

6.0

0.4C

< 0.02

5.9

0.4D

< 0.02

5.9

0.4E

< 0.02

5.9

0.4F

< 0.02

5.8

 

 

 

 Table 2        Measurements of water solubility at 20°C

Column flow rate 0.2 mL/minute 

Sample

Solubility

pH

number

(mg/L)

 

 

 

 

0.2A

< 0.02

6.5

0.2B

< 0.02

6.2

0.2C

< 0.02

6.0

0.2D

< 0.02

6.6

0.2E

< 0.02

7.1

 

 

Conclusions:
The test item, was found to have a water solubility of less than 0.02 mg/L at 20°C.

Description of key information

Water solubility of the test item at 20°C is at less than 0.02 mg/L.

Key value for chemical safety assessment

Water solubility:
0.02 mg/L
at the temperature of:
20 °C

Additional information