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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Reference
Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Justification for type of information:
QSAR prediction
Guideline:
other: REACH Guidance on (Q)SAR
Principles of method if other than guideline:
(Q)SAR
Test organisms (species):
other: Green algae
Test type:
other: (Q)SAR
Water media type:
freshwater
Duration:
96 h
Dose descriptor:
EC50
Effect conc.:
4.353 mg/L
Dose descriptor:
other: Chronic Value (ChV)
Effect conc.:
1.416 mg/L
Validity criteria fulfilled:
yes
Remarks:
Aliphatic Amines: Maximum LogKow: 7.0 (Green Algae EC50) - 7.0 (Chronic Value)
Conclusions:
Estimated EC50 : 4.3 mg/L
Estimated Chronic Value : 1.4 mg/L
Intermediate substance is estimated to be toxic to aquatic algae with long lasting effects.

Description of key information

Short-term toxicity:

ECOSAR 1.11: Green Algae: EC50 (96h): 4.353 mg/L (2,5-Dichloropentylamine)

 

Long-term toxicity:

Indicated results for chronic toxicity are "Chronic values" as obtained from ECOSAR 1.11 (run on 2,5-Dichloropentylamine)

ECOSAR 1.11: Green Algae: ChV: 1.416 mg/L

Key value for chemical safety assessment

EC50 for freshwater algae:
4.3 mg/L
EC10 or NOEC for freshwater algae:
1.4 mg/L

Additional information

NOEC could be estimated to around 1.0 mg/L (ChV/√2) as indicated in Practical Guide 5 - How to use and report (Q)SARs 3.0 (March 2016)

Intermediate substance is estimated to be toxic to aquatic algae with long lasting effects.