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Ecotoxicological information

Long-term toxicity to aquatic invertebrates

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Reference
Endpoint:
long-term toxicity to aquatic invertebrates
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Justification for type of information:
QSAR prediction
Guideline:
other: REACH Guidance on (Q)SAR
Principles of method if other than guideline:
(Q)SAR
Test organisms (species):
other aquatic crustacea: Daphnid
Test type:
other: (Q)SAR
Water media type:
freshwater
Dose descriptor:
other: Chronic Value (ChV)
Effect conc.:
0.399 mg/L

See attachment in above summary: Aquatic toxicity - ECOSAR Program (v1.11) Results

Validity criteria fulfilled:
yes
Remarks:
Aliphatic Amines: Maximum LogKow: 8.0 (Chronic Value)
Conclusions:
Estimated Chronic Value : 0.39 mg/L
Intermediate substance is estimated to be toxic to aquatic invertebrates with long lasting effects.

Description of key information

Indicated results are "Chronic values" as obtained from ECOSAR 1.11 run on 2,5-Dichloropentylamine

Key value for chemical safety assessment

EC10, LC10 or NOEC for freshwater invertebrates:
0.39 mg/L

Additional information

NOEC could be estimated to around 0.28 mg/L (ChV/√2) as indicated in Practical Guide 5 - How to use and report (Q)SARs 3.0 (March 2016)

Intermediate substance is estimated to be toxic to aquatic invertebrates with long lasting effects.