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Boiling point

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Reference
Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
17-19 March 2014
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Remarks:
The study was conducted according to OECD/EU guideline, and under GLP. No deviation was reported. Test substance is adequately specified with purity. Therefore full validation applies.
Qualifier:
according to
Guideline:
OECD Guideline 103 (Boiling point/boiling range)
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.2 (Boiling Temperature)
Deviations:
no
Qualifier:
according to
Guideline:
EPA OPPTS 830.7220 (Boiling Point / Boiling Range)
Principles of method if other than guideline:
Not applicable
GLP compliance:
yes (incl. certificate)
Remarks:
inspected on January 22 and 23, 2013 / signed on March 22, 2013
Type of method:
differential scanning calorimetry
Key result
Boiling pt.:
207.5 °C
Atm. press.:
1 013 hPa
Decomposition:
no

The thermograms of the DSC runs are provided in the experimental report.

The test item showed a distinct endothermic signal in the temperature range of 100 - 220°C that can be associated with the boiling of the test item.

Table 4.3/1: Results of the DSC-measurements

 

Sample

Sample weight / mg

Onset of effect /°C

Range of effect /°C

Atmospheric pressure / hPa

1

12.43

207.71

100 - 220 (endo)

1007.7

2

11.20

206.99

100 - 220 (endo)

1011.4

 

For the correction of the boiling temperature to standard pressure, the test item was assigned to chemical group 3 (eg esters); therefore, a correction value C = 5.2 was used for the temperature range from 200 to 210°C.

The lowest measured onset temperature is corrected to the standard pressure to be 207.06 °C and the highest onset temperature to be 207.93 °C. As the corrected onset temperatures in both tests do not deviate by more than 0.5 K from their mean value of 207.5°C, this temperature is used as boiling point.

No further thermal effects were observed up to the test end temperature of 500 °C.

Executive summary:

The boiling point of the test substance was determined under GLP according to OECD 103/EU A2 guideline, by differential scanning calorimetry (DSC) method. Two main runs were performed under nitrogen atmosphere, and the mean temperature range was retained.

The boiling temperature of test substance has been determined to be 207.5°C corrected to normal atmospheric pressure (1013 hPa).

Description of key information

Boiling point = 207.5°C under inert atmosphere and corrected to standard atmP.

Key value for chemical safety assessment

Boiling point at 101 325 Pa:
207.5 °C

Additional information

A fully reliable experimental study, conducted according to a recognized OECD/EC method and under GLP, is available. It is considered as a key study, and the result is retained as key data.