Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 235-243-3 | CAS number: 12138-09-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2001-11-02 to 2002-02-11
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Version / remarks:
- Adopted 1984-04-04
- GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: 16031/01
- Purity test date: >98% - Analytical monitoring:
- yes
- Vehicle:
- no
- Details on test solutions:
- Stock Solution: The solution (100 mg/L tst item were weighed out) was prepared with dilution water one day prior to application.
Dispersion Treatment: The stock solution was stirred fr 24 h on a megnetic stirrer and filltrated with 0.45 um
Limit Concentration: Saturated solution (saturated concentration) - Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Common name: Daphnia magna STRAUS
- Strain/clone: Clone 5
- Origin: Institut fur Wasser-, Boden-und Lufthygiene ds Bundesundheitsamtes, Corrensplatz, 14195 Berlin, FRG
ACCLIMATION
- Acclimation period:
- Acclimation conditions (same as test or not):
- Type and amount of food: Mix of Scenedesmus subspicatus and Chlorella vulgaris
- Feeding frequency: five times weekly ad libitum - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Post exposure observation period:
- Number of Dahpnia incapable of swimming after 24 and 48 hours after exposure
- Hardness:
- Total hardness of 160 to 180 mg CaCo3/L
- Test temperature:
- 18-22 C, +/- 1C
- pH:
- 7.78
- Dissolved oxygen:
- 8.76 mg/L
- Nominal and measured concentrations:
- The mean measured concentration was 380 ug Tungsten/L
- Details on test conditions:
- TEST SYSTEM
- Test vessel: Glass beakers, 50 ml volume were used.
- Material, size, headspace, fill volume: volume of the study medium 20 ml
- No. of organisms per vessel: 5 for test and 10 for control
- No. of vessels per concentration (replicates): Four
- No. of vessels per control (replicates): Two
RANGE-FINDING STUDY
A preliminary range finding test was conducted under static conditions. 100 mg/L were weighed out, stirred 24 h and fitered with 0.45 before using. Three dilutions (1:1, 1:10, 1:100) of the stock solutions were carried out and used for the preliminary test. - Reference substance (positive control):
- yes
- Remarks:
- Potassuim dichromate
- Key result
- Duration:
- 24 h
- Dose descriptor:
- NOEC
- Effect conc.:
- > 380 µg/L
- Nominal / measured:
- meas. (initial)
- Conc. based on:
- test mat. (dissolved fraction)
- Remarks:
- Tested saturation concentration
- Basis for effect:
- mobility
- Key result
- Duration:
- 48 h
- Dose descriptor:
- NOEC
- Effect conc.:
- > 380 µg/L
- Nominal / measured:
- meas. (initial)
- Conc. based on:
- test mat. (dissolved fraction)
- Remarks:
- Tested saturation concentration
- Basis for effect:
- mobility
- Duration:
- 24 h
- Dose descriptor:
- EC50
- Remarks:
- Confidence Interval
- Effect conc.:
- > 2.2 - < 2.6 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- other: Reference Substance: Potassium dichromate
- Validity criteria fulfilled:
- yes
- Remarks:
- Values of the reference substance (potassium dichromate) and control group after the 24 hours were fulfilled: 24h-EC50 range of 1.0 t0 2,5 mg/L, pH-value did not vary by more than 1 unit, dissolved O2 >5.2 mg/L
- Conclusions:
- At the saturation concentration (380 ug of W/L) tungsten disulphide no biologically significant effect was determined.
- Executive summary:
There is short-term toxicity to aquatic invertebrates data available for tungsten disulphide. In the acute immobilisation test withDaphnia magna(STRAUS) the effect of the saturated concentration as limit concentration of the test item tungsten disulphide was determined according to OECD Guideline 202/EEC Directive 92/69/EEC Method C.2. The test item was clearly dissolved throughout exposure in the tested limit concentration. The study was conducted under static conditions over a 48 hour period. 20 test organisms were exposed to the saturation concentration and control. Concentration control analysis was carried out and reported by an external GLP laboratory. Tungsten was determined via ICP-MS. 200 mL were sampled at the beginning and end of the test. The mean measure concentration was 380 ug/L (as dissolved tungsten). In the satuation concentration (380 ug/L) no biologically significant effect was determined.
Reference
Description of key information
There is short-term toxicity to aquatic invertebrates data available for tungsten disulphide. In the acute immobilisation test with Daphnia magna (STRAUS) the effect of the saturated concentration as limit concentration of the test item tungsten disulphide was determined according to OECD Guideline 202/EEC Directive 92/69/EEC Method C.2. The test item was clearly dissolved throughout exposure in the tested limit concentration. The study was conducted under static conditions over a 48 hour period. 20 test organisms were exposed to the saturation concentration and control. Concentration control analysis was carried out and reported by an external GLP laboratory. Tungsten was determined via ICP-MS. 200 mL were sampled at the beginning and end of the test. The mean measure concentration was 380 ug/L. In the saturation concentration (380 ug/L) no biologically significant effect was determined.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 380 µg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.