Registration Dossier

Administrative data

Endpoint:
eye irritation: in vivo
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Justification for type of information:
Corrosive potential of R-camphorsulfonic acid is due to sulfonic acid moiety. Thus, this substance classification is based on read across from sulfonic acids such as methanesulfonic acid.

Data source

Reference
Reference Type:
publication
Title:
HSDB

Materials and methods

Test animals / tissue source

Species:
rabbit

Results and discussion

Applicant's summary and conclusion

Conclusions:
Methane sulfonic acid (purity >99%) is extremely corrosive to the eye of rabbits.
Executive summary:

Methanesulfonic acid was corrosive to rabbit eyes and caused immediate pain and necrosis of all ocular tissue.