Registration Dossier

Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
read-across based on grouping of substances (category approach)
Adequacy of study:
key study
Justification for type of information:
It is well established that saturated perfluorocarbons form a class of chemicals with very similar properties.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1989
Report Date:
1989

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 203 (Fish, Acute Toxicity Test)
GLP compliance:
yes (incl. certificate)

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
liquid
Specific details on test material used for the study:
Batch 51178/B

Test solutions

Vehicle:
yes
Remarks:
50% w/w megaface F142-D

Test organisms

Test organisms (species):
other: Rainbow trout (salmo gairdneri)
Details on test organisms:
20 fish in each group

Study design

Test type:
semi-static
Water media type:
freshwater
Total exposure duration:
96 h

Test conditions

Hardness:
350 mg/l as CaCO3 (noted as slightly higher than recommended, but not considered to have had an effect)
Test temperature:
14 +/- 1°C
Dissolved oxygen:
>= 9.8 mg O2/l
Nominal and measured concentrations:
100 mg/l
Rebewed daily
Details on test conditions:
100 mg/l was the highest concentration that could be tested because of the very low solubility of the material in water and the toxicity of the vehicle at high contrations.

Results and discussion

Effect concentrations
Key result
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
> 100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality
Details on results:
No adverse effects were observed.

Applicant's summary and conclusion

Conclusions:
Material is not toxic to fish.
Executive summary:

Material is not toxic to fish.