1,3,5-tris(oxiranylmethyl)-1,3,5-triazine-2,4,6(1H,3H,5H)-trione

Endpoint summary

Additional information

The acute aquatic toxicity has been tested for TGIC.

Only limited ecotoxicological data for TGIC are available. The 96 h LC50 obtained in static studies on zebra fish (Brachydanio rerio) exceeded 77 mg/L (average of measured concentrations at 0 and 96 h), and the 96 hour NOEC was also 77 mg/l. The 24 h EC50 in a static Daphnia magna immobilisation test was above 100 mg/L, with a NOEC of 58 mg/L. The 72 -hour toxicity in green algae (sacenedesmus subspicatus) showed an EbC50 (growth of algae) of 29 mg/l and a NOEC = 6.3 mg/l. These results indicate that TGIC is, at most, moderately toxic to aquatic fauna under conditions of acute exposure.

Environmental exposure to TGIC is expected to be minimal as dust extractors and other pollution control devices will remove particulate waste for disposal. TGIC contained in such waste will be effectively immobile after consignment to landfill, particularly if most waste powder is heat cured beforehand. Any residues which remain free and enter the open environment will have limited persistence because of the lability of the epoxide substituents. As an example of release from a formulation plant, ICI Dulux estimates daily releases of TGIC to sewer of 15 kg. Passage through Werribee Treatment Complex (500 ML daily flow) would dilute this release to a concentration of 30 ppb, assuming that mixing is uniform and no removal takes place. This clearly provides an adequate safety margin for aquatic fauna, even when other waste streams containing TGIC are added, since the NOEC for daphnids was some 1000 times this level. The predicted environmental hazard is low.(Taken from NICNAS, (1994), Priority Existing Chemical No. 1 - Triglycidyl Isocyanurate, full Public Report, National Industrial Chemicals Notification and Assessment Scheme. Canberra, Australian Government Publishing Services, April 1994.)