Registration Dossier
Registration Dossier
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EC number: 202-282-2 | CAS number: 93-84-5
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1992-06-05 to 1992-07-03
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: According to guideline OECD 301B but toxicity control is missing. Toxicity to microorganism according to guideline OECD 209. EC 50 > 1000 mg/l
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 992
- Report date:
- 1992
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Deviations:
- not specified
- GLP compliance:
- yes
Test material
- Reference substance name:
- 1,3-dihydro-5-nitro-2H-benzimidazol-2-one
- EC Number:
- 202-282-2
- EC Name:
- 1,3-dihydro-5-nitro-2H-benzimidazol-2-one
- Cas Number:
- 93-84-5
- Molecular formula:
- C7H5N3O3
- IUPAC Name:
- 5-nitro-1,3-dihydro-2H-benzimidazol-2-one
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- sewage, predominantly domestic, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): Local STP Frankfurt-Sindlingen
- Pretreatment: filtered (folded filter)
- Concentration of sludge: 10 ml/l - Duration of test (contact time):
- 28 d
Initial test substance concentrationopen allclose all
- Initial conc.:
- 5.57 mg/L
- Based on:
- DOC
- Initial conc.:
- 11.13 mg/L
- Based on:
- DOC
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- CO2 evolution
Reference substance
- Reference substance:
- benzoic acid, sodium salt
- Remarks:
- 2g/L in H2Odest, pH 7.2, DOC = 1168,5mg/L (C), Used 10mL/L resulting in a final concentration of 11,67mg/L(C) as DOC
Results and discussion
% Degradation
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 21
- Sampling time:
- 28 d
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- under test conditions no biodegradation observed
- Executive summary:
Under the given test conditions no biodegradation is observable. According to definitions found in OECD TG Nitrolon is not readily biodegradable. CO2 -evolution caused during 28d of degradation of Nitrolon was 21%.
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