Registration Dossier
Registration Dossier
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EC number: 205-426-2 | CAS number: 140-66-9
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Endpoint concentration was reported as EC50 >10 mg octylphenol/L for the activated sludge mixture, and EC10 >1,700 mg octylphenol/L for Pseudomonas putida.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 10 mg/L
- EC10 or NOEC for microorganisms:
- 1 700 mg/L
Additional information
Reliable toxicity data for a study of octylphenol exposure to microorganisms included Hϋls (1991) withPseudomanas putida, and a study by Safepharm (1991) using a mixture of activated sludge microorganisms. Test durations ranged from 3 hr (mixture) to 5 hr (Pseudomonas putida) with endpoints determined by inhibition of respiration rate. Endpoint concentration was reported as EC50 >10 mg octylphenol/L for the activated sludge mixture, and EC10 >1,700 mg octylphenol/L forPseudomonas putida. Both of these studies were selected as key studies.
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