Registration Dossier
Registration Dossier
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EC number: 701-028-2 | CAS number: -
Toxicity to microorganisms
Administrative data
- Endpoint:
- toxicity to microorganisms, other
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2001
- Reliability:
- 2 (reliable with restrictions)
Cross-reference
- Reason / purpose for cross-reference:
- reference to same study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 001
- Report date:
- 2001
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: enhanced OECD 301D
- Principles of method if other than guideline:
- The study was an OECD 301D biodegradation study, though separate analysis was performed on the toxicity to the innoculum.
- GLP compliance:
- yes
Test material
- Reference substance name:
- 4-(2-methyloctyl)phenyl bis(4-nonylphenyl) phosphite
- EC Number:
- 701-028-2
- Cas Number:
- 26523-78-4
- Molecular formula:
- C45H69O3P
- IUPAC Name:
- 4-(2-methyloctyl)phenyl bis(4-nonylphenyl) phosphite
- Reference substance name:
- Nonylphenol
- EC Number:
- 246-672-0
- EC Name:
- Nonylphenol
- Cas Number:
- 25154-52-3
- IUPAC Name:
- 2-nonylphenol
- Test material form:
- liquid
Constituent 1
Constituent 2
Sampling and analysis
- Analytical monitoring:
- yes
Test solutions
- Vehicle:
- no
- Details on test solutions:
- 15.4 mg/L was added to each replicate.
Test organisms
- Test organisms (species):
- other: Polyseed Commerical BOD innoculum
- Details on inoculum:
- Polyseed is a commerical bacterial inncolum encapsulated and used primarily for BOD studies.
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 28 d
Test conditions
- Test temperature:
- 20 +/- 1 deg C
- Dissolved oxygen:
- 7.8% initial ; 3.0% final
- Reference substance (positive control):
- yes
- Remarks:
- sodium acetate
Results and discussion
Effect concentrations
- Duration:
- 28 d
- Dose descriptor:
- EC0
- Effect conc.:
- 15.4 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth inhibition
- Details on results:
- No inhibition of growth. Test concentration is well in excess of water solubility.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- No inhibition of growth. Test concentration is well in excess of water solubility.
- Executive summary:
No inhibition of growth. Test concentration is well in excess of water solubility.
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