Bis(tributyltin) oxide

Water solubility

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

Not reported

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

GLP compliance:

yes

Type of method:

flask method

Water solubility:

71.2 mg/L

Temp.:

20 °C

Remarks on result:

other: Water solubility was recorded as the average of the 2 runs

Details on results:

An average value for the solubility of tri-n-butyltin oxide of 71.2 (± 1.5) mg/L was obtained from two independent runs.
The standard deviation of the mean values, s, was 4.3.
The repeatability of the runs is less than 11% and fulfls the required condition for repeatability < 15 % for the elution method.

Analytical Results

Run 1 (20°C)					Run 2 (20°C)
Sample	Orig. weight-in quantity in 100 ml water	pH	TBTO (mg/L)		Sample	Orig. weight-in quantity in 100 ml water	pH	TBTO (mg/L)
1 (24 hr)	101.5 mg	7.12	78.9		1 (24 hr)	102.4 mg	7.12	71.2
2 (48 hr)	105.2 mg	7.53	75.3		2 (48 hr)	101.7 mg	7.53	67.4
3 (72 hr)	102.1 mg	7.4	67.7		3 (72 hr)	100.8 mg	7.4	69.5
4 (96 hr)	105.0 mg	7.5	73.8		4 (96 hr)	100.8 mg	7.5	66.4
		Avg.	73.9				Avg.	68.6
		Std.	4.6				Std.	2.1

Conclusions:

The water solubility of tri-n-butyltin oxide was determined using an average of the results obtained from performing the flask method, was 71.2 mg/L at 20 °C.

Executive summary:

Using the flask method (OECD Guideline No. 105), the water solubility of tri-n-butyltin oxide was determined to be 71.2 (± 1.5) mg/L at 20 °C, or slightly soluble

Reference 2

Endpoint:

water solubility

Type of information:

other: Handbook

Adequacy of study:

supporting study

Study period:

not stated

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Principles of method if other than guideline:

Not reported

GLP compliance:

not specified

Type of method:

other: no information

Remarks on result:

other: Almost insoluble in water; miscible with organic solvents. Forms compounds with cellulosic and lignin-containing materials not easily decomposed or dissolved in water

No additional information

Conclusions:

Bis(tri-n-butyltin)oxide is characterized as "Almost insoluble in water; miscible with organic solvents. Forms compounds with cellulosic and lignin-containing materials not easily decomposed or dissolved in water."

Executive summary:

Bis(tri-n-butyltin)oxide is characterized as "Almost insoluble in water; miscible with organic solvents. Forms compounds with cellulosic and lignin-containing materials not easily decomposed or dissolved in water."

Reference 3

Endpoint:

water solubility

Type of information:

other: Handbook

Adequacy of study:

supporting study

Study period:

not stated

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Principles of method if other than guideline:

Not reported

GLP compliance:

not specified

Type of method:

other: no information

Water solubility:

18 - 19 mg/L

Temp.:

20 °C

Remarks on result:

other: pH not reported

Details on results:

The solubility is 18-19 mg/L at 20 °C in distilled water; 8-10 mg/L at 22 °C in seawater, 100 mg/L

No additional information

Conclusions:

The solubility is reported, in mg/L, as "18-19 at 20°C in distilled water; 8-10 at 22°C in seawater, 100 mg/L".

Executive summary:

The solubility of bis(tri-n-butyltin)oxide is reported, in mg/L, as "18-19 at 20 ºC in distilled water; 8 -10 at 22 ºC in seawater, 100mg/L"; this range would be considered slightly soluble.

Reference 4

Endpoint:

water solubility

Type of information:

other: Handbook

Adequacy of study:

supporting study

Study period:

not applicable

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Principles of method if other than guideline:

Not reported

GLP compliance:

not specified

Type of method:

other: no information provided

Water solubility:

18 - 19 mg/L

Temp.:

20 °C

Remarks on result:

other: pH not reported

Details on results:

Solubility 18-19 mg/L at 20 °C in distilled water; 8-10 mg/L at 22 °C in seawater. Handbook also reports 100 mg/L with no detail.

No additonal information

Conclusions:

The solubility of bis(tri-n-butyltin)oxide is reported as 18-19 mg/L at 20 °C in distilled water; 8-10 mg/L at 22 °C in seawater. Handbook also reports 100 mg/L with no detail.

Executive summary:

The solubility of bis(tri-n-butyltin)oxide is reported as 18-19 mg/L at 20 °C in distilled water; 8-10 mg/L at 22 °C in seawater. The handbook also reports 100 mg/L with no detail.

Reference 5

Endpoint:

water solubility

Type of information:

other: Handbook

Adequacy of study:

supporting study

Study period:

not aplicable

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Principles of method if other than guideline:

Not reported

GLP compliance:

not specified

Type of method:

other: measured

Water solubility:

< 20 other: ppm

Remarks on result:

other: in water at 20 °C

Water solubility:

0.1 other: %

Remarks on result:

other: In hot water

Water solubility:

4 mg/L

Temp.:

20 °C

pH:

7

Remarks on result:

other: Measured

Details on results:

The solubility is listed as 0.1% in hot water, <20 ppm in water at 20 °C; water solubility of 4 mg/L at pH 7.0 and 20 °C (measured).

No additional information

Conclusions:

The solubility of hexabutyldistannoxane, also know as bis(tri-n-butyltin)oxide, is listed as: 0.1% in hot water; <20 ppm in water at 20 °C; and water solubility of 4 mg/L at pH 7.0 and 20 °C (measured).

Executive summary:

The solubility of hexabutyldistannoxane, also know as bis(tri-n-butyltin)oxide, is listed as: 0.1% in hot water; <20 ppm in water at 20 °C; and water solubility of 4 mg/L at pH 7.0 and 20 °C (measured).

Description of key information

Using the flask method (OECD Guideline No. 105), the water solubility of tri-n-butyltin oxide was determined to be 71.2 (± 1.5) mg/L at 20 °C, (slightly soluble).

Key value for chemical safety assessment

Water solubility:

71.2 mg/L

at the temperature of:

20 °C

Additional information

The key study for this data requirement, Ventur D (1989) was selected as it was considered the most reliable of the presented data. The study was performed in compliance with GLP and in line with the OECD guideline 105 with good reporting of the methods and results. The study was assigned a reliability score of 1.

A further four references were included as supporting information, all were sourced from peer reviewed handbooks.

 

Lewis, RJ (2002), Hawley's Condensed Chemical Dictionary, 14th Edition

Verschueren, K (2001) Handbook of Environmental Data on Organic Chemicals (4th Edition)

Gangolli, S. ed. (2005) Dictionary of Substances and Their Effects (DOSE, 3rd Electronic Edition)

Prager, JC (1998) Environmental Contaminant Reference Databook, Volumes 1-3

 

The data all concurred that the substance is slightly soluble (though there was variation on the values reported). All were assigned a reliability score of 2.