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EC number: 208-807-1
CAS number: 542-28-9
With high probability acutely not harmful to aquatic organisms. The
inhibition of the degradation activity of activated sludge is not
anticipated when introduced in appropriate low concentrations.
This aquatic toxicity assessment was based on the following data:
The acute toxicity of the test substance to zebra fish was
measured in a GLP guideline study according to OECD 203. Under the test
conditions no visible or lethal effects in zebra-fish at or below 120
mg/L (limit test) were observable (BASF SE 17F0426/11X322, 2013). Based
on these data, the test substance is considered to be "with high
probability acutely not harmful to fish".
In a static GLP test according to EU method C.2 the acute toxicity
of the substance to Daphnia magna was investigated (BASF 1998).
After 48 hours no effects were observed in the highest nominal test
concentration of 100 mg/L, indicating that the EC0 and EC50 are well
above 100 mg/L. Due to the analytics, an arithmetic mean concentration
of 74.7 mg/L was estimated. As already stated no effects occured in the
highest concentration. Therefore, it is assumed that the substance is
not harmful to aquatic invertebrates. Due to product saftey reasons the
measured arithmetic mean value of 74.7 mg/L is used for the subsequent
hazard assessment of the substance.
The toxicity of the test substance to the green algae Pseudokirchneriella
subcapitata was investigated in a GLP guideline study according to
OECD 201 (BASF SE 60E0426/11X323, 2013). In this study, the EC10 (72h)
on the growth rate was determined to exceed the highest measured
concentration of 142 mg/L (based on time weighted average). Based on
this outcome, the test substance is considered to be "with high
probability not harmful to aquatic algae".
As key study regarding toxicity to microorganisms a non-GLP test
according to OECD guideline 209 was performed using domestic activated
sludge as inoculum. After 30 minutes of exposure no respiration
inhibition could be observed resulting in a EC0 of 1000 mg/L (BASF
90/1170/08/1, 1990). As a further result an EC10 (16h) of 95 mg/L from a
test with Pseudomonas putida is available (BASF 1990). For PNEC
derivation the EC0 values from the OECD 209 test is used as the test is
more realistic for the assessment of toxicity to sewage works.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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