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Physical & Chemical properties

Particle size distribution (Granulometry)

Administrative data

Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
05 October 2009
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: No details on test material.

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
2009
Report Date:
2010

Materials and methods

Test guideline
Guideline:
other: no guideline mentioned
Principles of method if other than guideline:
Laser scattering/diffraction method. Distribution type: volume. Polydisperse. The instrument used as well as the test conditions are well described.
GLP compliance:
not specified
Type of distribution:
volumetric distribution

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
Sample file: ZOR0910
Sample ID: 1004918
Batch: D212013

Results and discussion

Particle sizeopen allclose all
Percentile:
D50
Mean:
22.98 µm
Remarks on result:
other: Migrated from fields under 'Mass median diameter' as D50 percentile. No source field for Standard deviation.
Percentile:
D10
Mean:
3.17 µm
Percentile:
D50
Mean:
18.66 µm
Percentile:
D90
Mean:
49.64 µm
Percentile:
D95
Mean:
59.99 µm
Particle size distribution at different passages
Size:
< 100 µm
Distribution:
100 %
Remarks on result:
other: inhalable fraction

Any other information on results incl. tables

About 30% of the test samples has particles < 10 µm (thoracic fraction).

About 13% of the test sample has particles < 4 µm (respirable fraction)

Applicant's summary and conclusion

Conclusions:
The test sample consists of 100% of inhalable particles (< 100%). The MMAD is 22.98 µm.