Registration Dossier

Administrative data

Endpoint:
explosiveness
Type of information:
experimental study
Adequacy of study:
key study
Study period:
02.09.2009 - 15.10.2009
Reliability:
1 (reliable without restriction)
Cross-referenceopen allclose all
Reason / purpose:
reference to same study
Reason / purpose:
reference to other study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2009
Report Date:
2009

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: UN Recommendations on the Transport of Dangerous Goods; Manual of Tests and Criteria, Fourth revised edition, 2003, Appendix 6, Orange Book
Deviations:
no
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
Constituent
Details on test material:
- Name of test material (as cited in study report): R-Pantolactone
- Physical state: solid
- Stability under test conditions: stable
- Storage condition of test material: RT (20°C)

Results and discussion

Small-scale preliminary testsopen allclose all
Parameter:
other: More sensitive to shock than m-dinitrobenzene
Remarks:
migrated information
Remarks on result:
not measured/tested
Parameter:
other: More sensitive to friction than m-dinitrobenzene
Remarks:
migrated information
Remarks on result:
not measured/tested
Parameter:
other: Explosive under influence of flame
Remarks:
migrated information
Remarks on result:
not measured/tested
Parameter:
other: Explosive (not specified)
Remarks:
migrated information
Remarks on result:
not measured/tested

Any other information on results incl. tables

The appraisal of the molecular structure indicates no risk of rapid decomposition. R-Pantolactone

does not contain any of the structural features mentioned in the UN Recommendations. The

occurrence of other chemical groups associated with explosive properties as described in the

literature1 was also considered. No such groups were present.

The oxygen balance was calculated using the equation given in the UN Recommendations.

Based on the molecular formula of C6H10O3 and a molecular weight of 130 g/mol, the oxygen

balance is about -172, which is above the limit of 200.

The calorimetric test is of special importance for the evaluation of compounds containing chemical groups associated with explosive properties. The decomposition energy (¿HDec determined between room temperature and 500 °C) was found to be about 27 J/g thus being far below the UN limit of 500 J/g. The onset point of the exothermic peak was at about 197°C.

1 L. Bretherick: Handbook of Reactive Chemical Hazards, London, Butterworth, 1979

Applicant's summary and conclusion

Conclusions:
R-Pantolactone is not to be classified as explosive material and no experimental determination according to the EC test guideline A.14
has to be performed.
Executive summary:

Based on the results above, R-Pantolactone is not to be classified as

explosive material and no experimental determination according to the EC test guideline A.14

has to be performed. Although the result of Section 3.2 (oxygen balance) is above the given limit

the deviation is small. Given the fact that all other criteria for R-Pantolactone being an explosive

material are negative, an experimental determination according to the EC test guideline A.14 has

not to be performed.

Thus it can be concluded beyond a reasonable doubt, that R-Pantolactone is not a potential

explosive and does not have a potential for rapid energy release. Nevertheless, this judgment is

in respect to classification; it does not necessarily mean that any processing hazards can be

discounted.