Registration Dossier
Registration Dossier
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EC number: 200-064-1 | CAS number: 50-78-2
Hydrolysis
Administrative data
- Endpoint:
- hydrolysis
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Data considerd as reliable because published by Umweltbundesant (German CAs). GLP not specified
Data source
Reference
- Reference Type:
- publication
- Title:
- No information
- Author:
- Umweltbundesant
- Year:
- 1 981
- Bibliographic source:
- OECD Guidelines for Testing of Chemicals. Berlin: Umweltbundesant pp. 842 (1981)
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 111 (Hydrolysis as a Function of pH)
- GLP compliance:
- not specified
Test material
- Reference substance name:
- O-acetylsalicylic acid
- EC Number:
- 200-064-1
- EC Name:
- O-acetylsalicylic acid
- Cas Number:
- 50-78-2
- Molecular formula:
- C9H8O4
- IUPAC Name:
- 2-acetoxybenzoic acid
- Test material form:
- solid: crystalline
Constituent 1
- Radiolabelling:
- no
Study design
- Analytical monitoring:
- yes
Results and discussion
Dissipation DT50 of parent compoundopen allclose all
- pH:
- 3.5
- Temp.:
- 20 °C
- DT50:
- 12.5 d
- Type:
- not specified
- pH:
- 5
- Temp.:
- 20 °C
- DT50:
- 5.4 d
- Type:
- not specified
- pH:
- 7.4
- Temp.:
- 20 °C
- DT50:
- 6.3 d
- Type:
- not specified
- pH:
- 9.5
- Temp.:
- 20 °C
- DT50:
- 2.2 d
- Type:
- not specified
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- The substance is readily hydrolysed at environmental pH.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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