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EC number: 202-050-0
CAS number: 91-21-4
The 30 -min EC50 value is >1000 mg/L in activated sludge from a municipal STP.
The toxicity of 1,2,3,4 -tetrahydroisoquinoline was determined in a
GLP-compliant Activated Sludge respiration Inhibition test according to
OECD guideline 209. In this study, activated sludge from the aeration
tank of a municipal wastewater treatment plant was exposed to nominal
concentrations of 10, 100, 240, 500 and 1000 mg/L and a blank control
for 30 minutes. No analytical verification of nominal concentrations was
performed. After the exposure period oxygen consumption rates were
measured using an oxygen electrode and the percentage inhibition of the
oxygen consumption was estimated by comparison of the rate with that of
a control mixture containing no test material (blank control). The
sensitivity of the activated sludge was checked with the reference
substance 3,5 dichlorophenole. After 30 minutes exposure, a maximum 47%
inhibition of oxygen consumption rate was noted at the highest
concentration of 1000 mg/L. Based on these findings the 30 -min EC50
value is determined at >1000 mg/L.
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