Registration Dossier

Environmental fate & pathways

Biodegradation in water: screening tests

Administrative data

Endpoint:
biodegradation in water: ready biodegradability
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Study performed in accordance with OECD Guideline and compliant with GLP criteria.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2002
Report Date:
2002

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
GLP compliance:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Substance name: 4-tert-Butyl-2,6-dimethylphenylacetonitrile

Study design

Oxygen conditions:
aerobic
Inoculum or test system:
activated sludge (adaptation not specified)
Details on inoculum:
Activated sludge from Iaboratory wastewater plant treating municipal sewage. Conc. of dry substance is ca. 30 mg/L.
Duration of test (contact time):
28 d
Initial test substance concentrationopen allclose all
Initial conc.:
24 mg/L
Based on:
test mat.
Initial conc.:
20 mg/L
Based on:
DOC
Parameter followed for biodegradation estimation
Parameter followed for biodegradation estimation:
CO2 evolution

Results and discussion

% Degradation
Value:
< 10
Sampling time:
28 d

Any other information on results incl. tables

Test concentration is equivalent to 20 mg/L TOC. Since the test substance  is poorly soluble in water, no DOC degradation was determined.

Applicant's summary and conclusion